Results 191 to 200 of about 372,530 (379)

Size exclusion chromatography of biopharmaceutical products: From current practices for proteins to emerging trends for viral vectors, nucleic acids and lipid nanoparticles.

open access: yesJournal of Chromatography A
V. D’Atri   +6 more
semanticscholar   +1 more source

Purification of filamentous bacteriophage for phage display using size-exclusion chromatography

open access: yesBioTechniques, 2005
Maria Yu. Zakharova   +5 more
doaj   +1 more source

Effective Penetration of the Oxidized Keratin‐Rebonding Materials Into Hair Shafts Based on Charge Conversion

open access: yesAdvanced Healthcare Materials, EarlyView.
We have developed a smart hair‐repair ingredient based on β‐carboxylic acid amide that undergoes negative‐to‐positive charge conversion under mildly acidic conditions. The initial negative charge facilitates deep penetration into the hair fiber, while the subsequent positive charge enables re‐bonding with sulfonate groups in damaged hair keratin.
Sunyoung Kang   +8 more
wiley   +1 more source

Living Materials Approach for In Situ Bio‐Polymers Production Using Bacillus Paralicheniformis in Microneedles

open access: yesAdvanced Healthcare Materials, EarlyView.
Dissolvable microneedle (MN) device containing Bacillus paralicheniformis. The polymeric matrix encapsulates and protects the bacteria, preserving their viability while enabling in situ production and release of γ‐polyglutamic acid. The bacteria are delivered into the skin via 500 µm‐long microneedles, and remain detectable on the skin 24 h post ...
Caroline Hali Alperovitz   +3 more
wiley   +1 more source

Simultaneous monitoring of multiple attributes of pyrrolobenzodiazepine antibody-drug conjugates by size exclusion chromatography – high resolution mass spectrometry

open access: hybrid, 2021
Florian Füssl   +8 more
openalex   +1 more source

High Performance Liquid Chromatography-Size Exclusion Chromatography (Hplc-Sec) As an Efficient Tool for The Quantification of Polymers

open access: yesTo Chemistry Journal, 2019
Poly (lactide-co-glycolide acid) ( PLGA) is an extraordinary well-described polymer and has excellent pharmaceutical properties like high biocompatibility and good biodegradability.
Shripad   +3 more
doaj  

Strategies to Improve the Lipophilicity of Hydrophilic Macromolecular Drugs

open access: yesAdvanced Healthcare Materials, EarlyView.
Hydrophilic macromolecular drugs can be successfully lipidized by covalent attachment of lipids, by hydrophobic ion pairing with negatively or positively charged surfactants, and by dry or wet reverse micelle formation. Lipophilicity enhancement of hydrophilic macromolecules has several benefits including stability and bioavailability improvement ...
Sera Lindner   +8 more
wiley   +1 more source

Photosensitizing Lipid Nanoparticles for Ferroptosis‐Enhanced Photodynamic Cancer Therapy via GPX4 Silencing

open access: yesAdvanced Healthcare Materials, EarlyView.
Photosensitizing lipid nanoparticles (PLNPs) are engineered by incorporating cholesterol–PEG–pheophorbide a into MC3‐based LNPs and encapsulating GPX4‐targeting siRNA. Upon light activation, PLNPs generate reactive oxygen species (ROS) while silencing GPX4 to induce ferroptosis.
Ga‐Hyun Bae   +9 more
wiley   +1 more source

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