Results 61 to 70 of about 372,530 (379)

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

open access: yesFEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang   +5 more
wiley   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

open access: yesFEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang   +9 more
wiley   +1 more source

Glutamine Phosphoribosylpyrophosphate Amidotransferase-independent Phosphoribosyl Amine Synthesis from Ribose 5-Phosphate and Glutamine or Asparagine [PDF]

open access: yes, 2007
Phosphoribosylamine (PRA) is the first intermediate in the common pathway to purines and thiamine and is generated in bacteria by glutamine phosphoribosylpyrophosphate (PRPP) amidotransferase (EC 2.4.2.14) from PRPP and glutamine.
Downs, Diana M.   +2 more
core   +2 more sources

The importance of extracellular vesicle purification for downstream analysis: A comparison of differential centrifugation and size exclusion chromatography for helminth pathogens

open access: yesPLoS Neglected Tropical Diseases, 2019
Background Robust protocols for the isolation of extracellular vesicles (EVs) from the rest of their excretory-secretory products are necessary for downstream studies and application development.
Chelsea N. Davis   +6 more
semanticscholar   +1 more source

Size-Exclusion Chromatography as a Technique for the Investigation of Novel Extracellular Vesicles in Cancer

open access: yesCancers, 2020
Simple Summary Extracellular vesicles (EVs) are small particles that are released by cancer cells, and they may hold vital information for researchers looking for early markers for diagnosis.
Daniel S K Liu   +6 more
semanticscholar   +1 more source

Mass spectrometry data and size exclusion chromatography profiles of Australian taipan venom toxins

open access: yesData in Brief, 2016
The compositions of paradoxin and taipoxin (PDx and TPx, respectively) were investigated using size exclusion chromatography (SEC) and nano-electrospray ionization mass spectrometry (nano-ESI-MS).
Julian A. Harrison, J. Andrew Aquilina
doaj   +1 more source

Simultaneous characterization of poly(acrylic acid) and polysaccharide polymers and copolymers

open access: yesAnalytical Science Advances, 2020
Copolymer products that result from grafting acrylic acid and other hydrophilic monomers onto polysaccharides have recently gained significant interest in research and industry.
Ruben Epping   +7 more
doaj   +1 more source

Molecular-mass distribution of humic substances from Arctic soils according to size exclusion chromatography

open access: yesPolish Polar Research, 2020
Humic substances are polydisperse mixtures of structurally complex matters with different molecular weights. The complexity of molecular composition of humic substances is reflected through their physical and chemical properties and results in diverse ...
Lodygin, Evgeny, Vasilevich, Roman
doaj   +1 more source

Isolation and characterization of urine microvesicles from prostate cancer patients: different approaches, different visions

open access: yesBMC Urology, 2021
Background Because of their specific and biologically relevant cargo, urine extracellular vesicles (EVs) constitute a valuable source of potential non-invasive biomarkers that could support the clinical decision-making to improve the management of ...
María García-Flores   +5 more
doaj   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Home - About - Disclaimer - Privacy