Results 121 to 130 of about 13,693,867 (238)

Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy

Molecular Oncology, EarlyView.
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen, Zhi Zhao, Henrik Horndalsveen, Maria Moksnes Bjaanæs, Bjørn Henning Grønberg, Tarje Halvorsen, Tesfaye Madebo, Marianne Aanerud, Jussi Koivunen, Kersti Oselin, Saulius Cicenas, Nina Helbekkmo, Jarkko Ahvonen, Maria Silvoniemi, Tine Norman Alver, Tonje Dalen, Åsa Kristina Öjlert, Saima Jamil Farooqi, Åslaug Helland, Vilde Drageset Haakensen   +19 more
wiley   +1 more source

Establishing Local Diagnostic Reference Levels in Adult Uroscan CT Examinations using Size-Specific dose Estimates (SSDE) and Ctdivol in Morocco [PDF]

CTDIvol is a commonly used dose metric in CT scans, calculated based on a 16 cm or 32 cm diameter phantom. However, CTDIvol does not provide an accurate representation of the patient’s actual dose.
S. Hadrach
core   +1 more source

Evaluating the relationship between size-specific dose estimates and effective dose in abdominal computed tomography examinations: a single Centre study

The volume computed tomography index (CTDIvol) displayed in the dose report of computed tomography (CT) examinations does not represent the actual patient dose, due to its insensitivity to varying patient size.
Godswill M. Effiong, Akpama Egwu Egong, Christopher A. Ishiekwen, Nneoyi O. Egbe, Glory Anthony Mark, Emmanuel O. Esien-Umo, Solomon E. David   +6 more
core   +1 more source

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

Molecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani, Dominic Guanzon, Andrew Lai, Katherin Scholz‐Romero, Sarah Reed, Edita Ritmejeryte, Rohan Lourie, Naven Chetty, Kaltin Ferguson, Carlos Salomon   +9 more
wiley   +1 more source

The Impact of CARE kV Technology on Radiation Dose in Coronary Computed Tomography Angiography

CT Lilun yu yingyong yanjiu
Objective: To investigate the impact of CARE kV technology on radiation dose in coronary computed tomography angiography (CCTA). Methods: This retrospective study analyzed data from 1,529 patients who underwent CCTA at The First Affiliated Hospital of ...
Xinnan SHEN, Zhuohang ZHOU, Yiting WANG, Meiqi WANG, Yajing YANG, Zhiwei ZHANG   +5 more
doaj   +1 more source

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

Molecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira, Ana Teixeira‐Marques, Rui Freitas, João A Carvalho, Sara Monteiro‐Reis, Giorgio I. Russo, Rui Henrique, Carmen Jerónimo   +7 more
wiley   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

Molecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico, Veronica La Banca, Silvia D'Amico, Stefano Scalera, Sara Nicolai, Angelo Peschiaroli   +5 more
wiley   +1 more source

Influence of helical pitch and gantry rotation time on image quality and file size in ultrahigh-resolution photon-counting detector CT

Scientific Reports
The goal of this experimental study was to quantify the influence of helical pitch and gantry rotation time on image quality and file size in ultrahigh-resolution photon-counting CT (UHR-PCCT).
Philipp Feldle, Jan-Peter Grunz, Henner Huflage, Andreas Steven Kunz, Süleyman Ergün, Saif Afat, Philipp Gruschwitz, Lukas Görtz, Lenhard Pennig, Thorsten Alexander Bley, Nora Conrads   +10 more
doaj   +1 more source

Size-specific dose estimates for adult abdomen-pelvis computed tomography examinations in Johor [PDF]

, 2017
Accurate dose monitoring in computed tomography (CT) is important as CT provides high radiation exposure to the patient compared to other medical imaging modalities.
Bahrud Din, Nur Ashiqin
core  

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

Molecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin   +17 more
wiley   +1 more source