Results 191 to 200 of about 13,693,867 (238)

Validation of a Cellular Imaging‐Based Method as a Potential Biomarker for SPG4 Hereditary Spastic Paraplegia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Hereditary Spastic Paraplegia (HSP) comprises a group of rare genetic diseases characterized by length‐dependent axonal degeneration of the corticospinal tracts and dorsal columns, whose main clinical feature is spastic gait. Pathogenic variants in the SPG4 gene cause Spastic Paraplegia Type 4 (SPG4‐HSP), the most common form of HSP.
Gaia Fattorini, Valerio Licursi, Gianmarco Dalla Zanna, Flavio Dal Canto, Melissa Barghigiani, Nunzio Setola, Salvatore Rossi, Antonio Funcis, Filippo M. Santorelli, Gabriella Silvestri, Carlo Casali, Francesca Sardina, Cinzia Rinaldo   +12 more
wiley   +1 more source

Disease Course After Anti‐CD20 Discontinuation in Secondary Progressive Multiple Sclerosis—A Multicenter Long‐Term Longitudinal Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To describe long‐term outcomes after anti‐CD20 discontinuation in selected patients with secondary progressive multiple sclerosis (SPMS) who remained without subsequent disease‐modifying therapy (DMT). Methods We retrospectively analyzed data from four centers in Austria and Switzerland.
Ferdinand Otto, Dariia Kliushnikova, Richard Friedrich Radlberger, Sinan Yasaroglu, Tobias Moser, Andrea Harrer, Kitty Kratzer, Wolfgang Hitzl, Christiane Gradl, Martin Schmidauer, Patrick Roth, Harald Hegen, Peter Wipfler   +12 more
wiley   +1 more source

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Size-Specific Dose Estimates for Evaluation of Individual Patient Dose in CT Protocol for Renal Colic

American Journal of Roentgenology, 2015
The purpose of this study is to retrospectively evaluate size-specific dose estimates of a renal-colic CT protocol and to assess the quality and diagnostic value of obtained images.The study population included 82 consecutive adult patients with acute renal colic undergoing CT with a reduced radiation dose (noise index, 59.1).
Maciej Guziński
exaly   +3 more sources

The role of Size-Specific Dose Estimate (SSDE) in patient-specific organ dose and cancer risk estimation in paediatric chest and abdominopelvic CT examinations

European Radiology, 2015
To develop a clinically applicable method to estimate patient-specific organ and blood doses and lifetime attributable risks (LAR) from paediatric torso CT examinations.Individualized voxel models were created from full-body CT data of 10 paediatric patients (2-18 years).
Caro, Franck, Charlot, Vandevoorde, Ingeborg, Goethals, Peter, Smeets, Eric, Achten, Koenraad, Verstraete, Hubert, Thierens, Klaus, Bacher   +7 more
openaire   +3 more sources

Optimizing CT Radiation Dose Based on Patient Size and Image Quality: The Size-Specific Dose Estimate Method

Pediatric Radiology, 2014
The principle of ALARA (dose as low as reasonably achievable) calls for dose optimization rather than dose reduction, per se. Optimization of CT radiation dose is accomplished by producing images of acceptable diagnostic image quality using the lowest dose method available.
David B. Larson
exaly   +3 more sources

Evaluating Size-Specific Dose Estimate (SSDE) as an Estimate of Organ Doses From Routine CT Exams Derived From Monte Carlo Simulations

Medical Physics, 2021
PURPOSE: The size specific dose estimate (SSDE) is a metric that adjusts CTDIvol to account for patient size. While not intended to be an estimate of organ dose, AAPM Report 204 notes the difference between the patient organ dose and SSDE is expected to ...
Michael McNitt-Gray, Maryam Khatonabadi, Christopher H Cagnon   +2 more
exaly   +2 more sources

Technical note: Advancing size‐specific dose estimates in CT examinations: Dose estimates at longitudinal positions of scans

Medical Physics, 2021
PurposeAmerican Association of Physicists in Medicine (AAPM) (Report 204) introduced the size‐specific dose estimate (SSDE) for the average dose to the center of a fixed‐mA scan. International standards establish a method that CT manufacturers and radiation dose index monitoring software may use to calculate SSDE(z) at longitudinal positions of scans ...
Xinhua, Li, Theodore A, Marschall, Kai, Yang, Bob, Liu   +3 more
openaire   +2 more sources

The impact of patient table on size-specific dose estimate (SSDE)

Australasian Physical & Engineering Sciences in Medicine, 2016
The use of parameters water equivalent diameter (D W ) and size-specific dose estimate (SSDE) are becoming increasingly established as a recognised method to relate patient dose from a CT examination to the dose indicator volume CT dose index (CTDIVOL).
Choirul, Anam, Freddy, Haryanto, Rena, Widita, Idam, Arif, Geoff, Dougherty, Donald, McLean   +5 more
openaire   +2 more sources

Simplifying Size-Specific Radiation Dose Estimates in Pediatric CT

American Journal of Roentgenology, 2015
Size-specific dose estimates (SSDEs) require manual measurement of torso diameters for individual patients--anteroposterior (hereafter, D(AP)), lateral (hereafter, D(LAT)), and effective (hereafter, D(E))--which can be tedious in clinical settings. We aimed to determine whether body weight can be used as a surrogate for measuring diameter in children.D(
Ranish Deedar Ali, Khawaja, Sarabjeet, Singh, Beth, Vettiyil, Ruth, Lim, Michael, Gee, Sjirk, Westra, Mannudeep K, Kalra   +6 more
openaire   +2 more sources

A comparison study of size-specific dose estimate calculation methods

Pediatric Radiology, 2017
The size-specific dose estimate (SSDE) has emerged as an improved metric for use by medical physicists and radiologists for estimating individual patient dose. Several methods of calculating SSDE have been described, ranging from patient thickness or attenuation-based (automated and manual) measurements to weight-based techniques.To compare the ...
Roshni A, Parikh, Michael A, Wien, Ronald D, Novak, David W, Jordan, Paul, Klahr, Stephanie, Soriano, Leslie, Ciancibello, Sheila C, Berlin   +7 more
openaire   +2 more sources