Results 91 to 100 of about 34,933 (276)

Chronic Dry Eye Disease is Principally Mediated by Effector Memory Th17 Cells [PDF]

, 2014
Recent experimental and clinical data suggest that there is a link between dry eye disease (DED) and T cell-mediated immunity. However, whether these immune responses are a consequence or cause of ocular surface inflammation remains to be determined ...
Chauhan, Sunil K., Chen, Yihe, Dana, Reza, Lee, Hyun Soo, Saban, Daniel R.   +4 more
core   +1 more source

Drug‐Induced Raynaud's Phenomenon and Underlying Mechanism: A Disproportionality Analysis From the World Health Organization Pharmacovigilance Database

Arthritis &Rheumatology, EarlyView.
Objectives The aim of this study is to generate hypotheses about unknown drugs associated with the onset or worsening of Raynaud's phenomenon (RP) and to explore their potential pathophysiologic mechanisms through a mixed disproportionality/clustering analysis from the World Health Organization (WHO) pharmacovigilance database.
Alex Hlavaty, Loubna Dari, Jean‐Luc Cracowski, Matthieu Roustit, Charles Khouri   +4 more
wiley   +1 more source

Long‐Term Outcomes of Reduced Intensity Conditioning Hematopoietic Stem Cell Transplantation for Systemic Sclerosis Patients with Impaired Cardiac Function

Arthritis &Rheumatology, Accepted Article.
Objective High intensity conditioning autologous hematopoietic stem cell transplantation (AHSCT) is standard of care for patients with advanced SSc. The role of reduced intensity conditioning (RIC) prior to AHSCT in this population remains unclear. We conducted this study to determine the long‐term outcomes of RIC AHSCT in SSc patients with cardiac ...
Yonatan Lean, Carrie Richardson, Anthony Esposito, Katy Bedjeti, George E. Georges   +4 more
wiley   +1 more source

Psychiatric disorder as clinical presentation of primary Sjögren's syndrome: two case reports

Annals of General Psychiatry, 2010
Psychiatric disorders in primary Sjögren's syndrome constitute a possible clinical reality that each practitioner must be able to recognise and treat.
Bonacini Federica, Pelizza Lorenzo, Ferrari Alberto   +2 more
doaj   +1 more source

Differential peripheral B cell phenotype in patients with primary Sjögren’s syndrome (pSS) compared to secondary Sjögren’s syndrome associated with systemic lupus erythematosus (SS/SLE) [PDF]

, 2016
Introduction: Peripheral B-cell abnormalities, a feature of both systemic lupus erythematosus (SLE) and primary Sjogren’s syndrome (pSS), are implicated in the pathogenesis of both diseases and correlate with disease activity.
Ciurtin, C, Isenberg, DA, Jury, E, Thompson, NL   +3 more
core  

An analysis of oral biopsies extracted from 1995 to 2009, in an oral medicine and surgery unit in Galicia (Spain) [PDF]

, 2011
Objective: To conduct an analysis of the frequency of oral lesions in biopsies over a 14-year period in the Oral Medicine, Oral Surgery and Implantology Unit.
Diniz Freitas, Márcio, García García, Abel, Gándara Rey, José Manuel, Sixto Requeijo, Raquel, Torreira Lorenzo, Juan Carlos   +4 more
core   +1 more source

Glucagon‐Like Peptide‐1 Receptor Agonists, Sodium‐Glucose Cotransporter‐2 Inhibitors, and Risk of Autoimmune Rheumatic Diseases

Arthritis &Rheumatology, Accepted Article.
Objective GLP‐1 receptor agonists (GLP‐1RAs) and SGLT2 inhibitors (SGLT2is) facilitate weight loss and exhibit immunomodulatory effects, but their impact on the risk of developing autoimmune rheumatic diseases (ARDs) is unclear. We compared ARD incidence following initiation of GLP‐1RAs, or SGLT2is, vs.
Derin Karacabeyli, Diane Lacaille, Na Lu, Hui Xie, J. Antonio Aviña‐Zubieta   +4 more
wiley   +1 more source

Labial salivary gland biopsy: a crucial method for confirming seronegative Sjogren’s syndrome—a case report

Bulletin of the National Research Centre
Background Sjogren’s syndrome is an autoimmune disease that affects exocrine glands like sweat glands, salivary glands, and lacrimal glands. Dentists frequently encounter these patients and have an important role in establishing the diagnosis.
Satyasai S. G. Romala, Kishore Moturi, Ravikanth Manyam, Meghana Vadupu, P. Divya Naga Lakshmi, Anil Budumuru, U. Shivajiraju, J. S. D. N. Sai Hyma, R. V. S. N. S. Ramachandrudu   +8 more
doaj   +1 more source

Primary Sjögren’s syndrome with polymyositis, a rare amalgamation

Egyptian Rheumatology and Rehabilitation, 2018
Sjögren’s syndrome is characterized by diminished lacrimal and salivary gland secretory function. This disorder is not strictly confined to the exocrine glands and its manifestations may extend to extraglandular sites, such as the lungs, kidneys ...
Harpreet Singh, Deepak Jain, B Kiran, Neeraj Kumar   +3 more
doaj   +1 more source

Autonomic symptoms are common and are associated with overall symptom burden and disease activity in primary Sjögren's syndrome [PDF]

, 2011
Objectives - To determine the prevalence of autonomic dysfunction (dysautonomia) among patients with primary Sjögren's syndrome (PSS) and the relationships between dysautonomia and other clinical features of PSS.
Andrews, J., Bombardieri, M., Bowman, S., Cooper, A., Dasgupta, B., Emery, P., Frith, J., Giles, I., Griffiths, B., Gupta, M., Hackett, K., Hunter, J., Isenberg, D., Jones, A., Lanyon, P., Lendrem, D., McLaren, J., Mitchell, S., Moots, R., Newton, J.L., Ng, W.-F., Pease, C., Pitzalis, C., Powell, D., Price, E., Regan, M., Sutcliffe, N., Vadivelu, S., Wilton, K., Young-Min, S.   +29 more
core   +3 more sources