Results 151 to 160 of about 37,519 (224)

Sex Matters: Hormonal and Chromosomal Determinants of Autoimmunity and Anti‐Cancer Immunity Across the Lifespan

Immunological Reviews, Volume 338, Issue 1, March 2026.
ABSTRACT Sex plays a key role in shaping both anti‐cancer immunity and autoimmunity. Biological factors underlying sexual dimorphism have now been identified in multiple aspects of anti‐cancer immunity and autoimmunity. These factors include sex differences in hormone levels, chromosome complement, and expression of the long non‐coding RNA XIST.
Christian G. Bustillos, Esther M. Peluso, Sophia L. Cha, Melissa G. Lechner, Maureen A. Su   +4 more
wiley   +1 more source

The X Factor in Immunity: Sex Differences Shaped by the X Chromosome

Immunological Reviews, Volume 338, Issue 1, March 2026.
ABSTRACT There are sex differences with immune responses where females exhibit stronger immune responses compared to males. Both sex hormones and sex chromosome differences between males and females contribute to the observed sex differences with innate and adaptive immune cell composition and function.
Katherine B. Radovanovic, Megan Wynalda, Montserrat C. Anguera   +2 more
wiley   +1 more source

Clinical profiles associated with rapidly progressive interstitial lung disease in antisynthetase syndrome: A multicentric cohort study (TYPASS study)

Journal of Internal Medicine, Volume 299, Issue 3, Page 365-380, March 2026.
Abstract Objectives To assess factors associated with rapidly progressive interstitial lung disease (ILD) (RP‐ILD) at time of ILD diagnosis in a multicentric retrospective cohort study of antisynthetase syndrome (ASyS). We used a complementary unsupervised approach, hierarchical clustering, to delineate distinct phenotypes among ASyS patients with ILD.
Maxime Billotte, Thomas Moulinet, Alain Meyer, Houda Camara, Loïs Bolko, Kévin Didier, Sandra Dury, Bernard Bonnotte, Hervé Devilliers, Philippe Bonniaud, Guillaume Beltramo, Julien Campagne, Nadine Magy‐Bertrand, Aurore Chaudier, Simon Valentin, Roland Jaussaud, Paul Decker   +16 more
wiley   +1 more source

Type I Interferon Gene Expression and Its Association With Ocular Involvement in Systemic Lupus Erythematosus

ACR Open Rheumatology, Volume 8, Issue 2, February 2026.
Objective Severalstudies have highlighted the role of Type I interferons (IFN‐I) in activating inflammatory pathways in lupus. However, no previous research focused on investigating the role of IFN‐I gene expression in the ophthalmologic involvement of systemic lupus erythematosus (SLE).
Raphael Teixeira Costa, Werbson Lima Guaraná, Braziliano Miguel da Silva Júnior, Jaciel Clementino, Luís Sousa Inês, Paula Sandrin‐Garcia, Thiago Sotero Fragoso   +6 more
wiley   +1 more source

Macrophage Activation Syndrome–Associated Proteins and Enhanced Interferon‐γ Responsiveness in the Plasma Proteome of Patients With Multisystem Inflammatory Syndrome in Children in a Pretreatment Replication Single‐Center Cohort

ACR Open Rheumatology, Volume 8, Issue 2, February 2026.
Objective Multisystem inflammatory syndrome in children (MIS‐C) is a rare hyperinflammatory syndrome that follows SARS‐CoV‐2 infection. Prior plasma proteomic analysis from a 2020 cohort of patients with MIS‐C at our center revealed a profile characterized by thrombotic microangiopathy (TMA), macrophage activation syndrome (MAS)‐associated proteins ...
Sarah McCuaig, Cara Toland, Katharine C. Konvinse, Emily Yang, Paul J. Utz, Laura A. Vella, Audrey R. Odom John, Hamid Bassiri, Edward M. Behrens   +8 more
wiley   +1 more source

Chronic rhinosinusitis is a risk factor for interstitial lung disease in Sjogren's syndrome. [PDF]

BMC Pulm Med
Schonewald B, Xie C, Engel A, Summer R, Loizidis G.   +4 more
europepmc   +1 more source

A relapsing inflammatory syndrome and HHV-8 [PDF]

, 2005
Dogan, A, Du, MQ, Isaacson, PG
core  

Multiomics Analyses Reveal an Essential Role of Tryptophan in Treatment of csDMARDs in Rheumatoid Arthritis

Advanced Science, Volume 13, Issue 9, 13 February 2026.
Rheumatoid arthritis is a disease characterized by joint inflammation. Approximately 50% of patients show insufficient response to traditional synthetic disease‐modifying antirheumatic drugs. This study aims to elucidate differential molecular profiles of the mechanisms underlying drug responses through multi‐omics strategy.
Congcong Jian, Jing Zhu, Jianhong Wu, Yan Zhang, Jianghua Chen, Huan Wang, Hengyan Liu, Ke Xu, Jiaxin Huang, Xiaoting Zhu, Yuanli Wei, Shilin Li, Tingting Wang, Xuan Huang, Qinghua Zou, Jie Zhang, Jiang Su, Xinming Du, Yaping Lu, Tianci Zhou, Yingtong Zhou, Minglong Tang, Bin Li, Xue Zhou, Qihao Wei, Qiulong Yan, Fanxin Zeng   +26 more
wiley   +1 more source

Meningoencephalitis as a presentation of primary Sjögren's syndrome: a case report. [PDF]

J Med Case Rep
Karim AK, Gorial FI, Badi IA, Mahdi FJ, Awadh NI, Hassan AM, Juma'a MK.   +6 more
europepmc   +1 more source

Clinical characteristics and biopsy accuracy in suspected cases of Sjögren’s syndrome referred to labial salivary gland biopsy [PDF]

, 2015

core   +1 more source