Results 131 to 140 of about 1,159,973 (256)

Saliva Liquid Biopsy for Detection of Oral and Systemic Diseases

Journal of Periodontal Research, EarlyView.
This Review summarizes and discusses the biological foundations and major classes of salivary biomarkers, outlines collection methods and analytical protocols for saliva‐based liquid biopsy, and technological convergences driven by multi‐omics approaches, artificial intelligence, and point‐of‐care devices in the application of oral and systemic ...
Irene Choi, Aaron Zander, Bradley Chan, Leila Syedmoradi, Dev Trivedi, Karolina Elżbieta Kaczor‐Urbanowicz, Fang Wei, Neeti Swarup, Trinity Chan, Mario Romandini, David T. W. Wong   +10 more
wiley   +1 more source

Sjögren's Syndrome With Distal Renal Tubular Acidosis and Hypokalemic Myopathy in Pregnancy: A Rare Case

Clinical Case Reports
Sjogren's syndrome may rarely present with distal renal tubular acidosis (dRTA), causing severe hypokalemia and myopathy. A 27‐year‐old primigravida at 15 weeks gestation presented with progressive proximal weakness and myalgia.
Nabiha Khan, Aasim Ali, Sadia Khan, Uzka Ghayour, Dipesh Kumar Yadav, Armaghana Abdullah   +5 more
doaj   +1 more source

AQP1 Corrects Acinar Cells’ Secretion Deficits in Sjögren's Disease

Oral Diseases, EarlyView.
ABSTRACT Introduction Sjögren's disease (SjD) is a systemic autoimmune disease characterized by dry mouth, dry eyes, and profound fatigue. Preclinical studies suggest that AQP1 gene expression in salivary glands corrects salivary hypofunction in preclinical and clinical studies of radiation‐induced xerostomia and improves salivary and lacrimal function
Paola Perez, Blake M. Warner, Youngmi Ji, Sandra Afione, Thomas J. F. Pranzatelli, Margaret E. Beach, Zohreh Khavandgar, Margie Grisius, Eileen Pelayo, Daniel Martin, NIDCD/NIDCR Genomics and Computational Biology Core, Alan N. Baer, John A. Chiorini   +12 more
wiley   +1 more source

Periodontal Disease and Salivary Gland Dysfunction in Neurofibromatosis Type 1: A Case–Control Study

Oral Diseases, EarlyView.
ABSTRACT Objectives Neurofibromatosis type 1 (NF1) presents with diverse systemic and oral manifestations. The aim of this study was to investigate the periodontal status and salivary alterations in NF1 individuals. Methods A total of 38 individuals with NF1 diagnostic criteria were compared with a control group paired by age and sex.
Eloá Borges Luna, Gustavo de Souza Vieira, Flávia Lima Kleinsorgen Motta, Ana Beatriz Oliveira Gambôa, Analúcia Rampazzo Xavier, Rafaela Elvira Rozza‐de‐Menezes, Karin Soares Cunha   +6 more
wiley   +1 more source

Sjögren’s syndrome and hepatitis C virus infection presenting as hypokalemic quadriparesis: A case report

Journal of International Medical Research
Distal renal tubular acidosis can present with acute-onset quadriparesis caused by severe hypokalemia, and primary Sjögren’s syndrome is a significant potential cause of distal renal tubular acidosis in such patients.
Ashish Joshi, Ujjwol Prasad Risal, Navin Kumar Sah, Bhupendra Shah   +3 more
doaj   +1 more source

Seronegative primary Sjögren’s syndrome, a distinct subtype of primary Sjögren’s syndrome in Chinese patients

Background To investigate the clinical and immune characteristics of patients with primary Sjögren’s syndrome (pSS) who were negative for anti–Sjögren’s-syndrome-related antigen A antibodies (anti-SSA) and anti–Sjögren’s-syndrome-related antigen B ...
Jingying Lan, Heqing Huang, Guixiu Shi, Yuan Liu, Yingying Shi, Jie Chen, Shiju Chen, Peishi Rao, Chaoqiong Deng, Yangchun Chen   +9 more
core   +1 more source

Salivary Apelin Levels and Periodontal Findings in Individuals With/Without Type 1 Diabetes and Varying Degrees of Gingival Inflammation

Oral Diseases, EarlyView.
ABSTRACT Objective To evaluate salivary apelin levels in individuals with and without type 1 diabetes presenting an intact periodontium and varying degrees of plaque‐induced gingival inflammation. Methods Saliva samples were collected; and whole‐mouth clinical periodontal measurements were recorded in type 1 diabetes and systemically healthy ...
Demet Efe Yavaşoğlu, Andressa V. B. Nogueira, Mehmet Demirbaş, Timur Köse, Sebahat Kaya, James Deschner, Nurcan Buduneli   +6 more
wiley   +1 more source

Oral Health–Related Quality of Life and Depressive Symptoms in Oral Mucosal Diseases: A Cross‐Sectional Observational Pilot Study

Oral Diseases, EarlyView.
ABSTRACT Objectives To evaluate the association between oral mucosal diseases, oral health‐related quality of life (OHRQoL), and depressive symptoms, and to explore differences across categories. Materials and Methods In this cross‐sectional observational pilot study, consecutive outpatients with oral mucosal disease were enrolled at the Dental Clinic ...
Domenico Cutecchia, Tommaso Marvulli, Vittorio Dibello, Alberta Lucchese, Massimo Petruzzi, Domenico De Falco   +5 more
wiley   +1 more source

Family Impact of Burning Mouth Syndrome: A Cross‐Sectional Study Using FROM‐16

Oral Diseases, EarlyView.
ABSTRACT Background Burning mouth syndrome (BMS) is a chronic oral pain condition associated with psychological distress and reduced quality of life. Although BMS' impact on patients is documented, family member impact remains poorly understood. This study evaluated family impact using Family Reported Outcome Measure (FROM‐16), explored family burden ...
Mona Jullie Hajj, Nicholas Sotak, Alessandro Villa, Alan Roger Santos‐Silva, Lloyd Mancl, Thaís Cristina Esteves‐Pereira, Milda Chmieliauskaite   +6 more
wiley   +1 more source

Pediatric Langerhans Cell Histiocytosis Presenting With Bilateral Parotid Gland Swelling and Cystic Lung Disease: A Case Report and Literature Review

Pediatric Dermatology, EarlyView.
ABSTRACT Langerhans cell histiocytosis (LCH) is a neoplastic process originating from immature myeloid precursor cells. In this report, we describe a case of a 17‐month‐old with scaling of the scalp and swelling of the bilateral parotid glands who developed acute respiratory distress.
Aretha On, Robert Smith, Robert Duffy, Maria B. Queenan, Melinda Jen   +4 more
wiley   +1 more source