Results 121 to 130 of about 37,390 (254)
People and Nature, EarlyView.Abstract Longer‐term perspectives—equivalent to the lifespans of long‐lived trees—are required to fully inform perceptions of ‘naturalness’ used in woodland conservation and management. Stand‐scale dynamics of an old growth temperate woodland are reconstructed using palaeoecological data.
Annabel Everard +4 more
wiley +1 more source
Rheumatology &Autoimmunity, EarlyView.Graphical abstract summarizing the multifactorial pathogenesis of rheumatoid arthritis (RA) and the therapeutic potential of mesenchymal stromal cell (MSC) therapy. MSCs provide promising benefits through their immunomodulatory properties, low immunogenicity, ability to promote tissue repair, and multi‐lineage differentiation, presenting a potential ...
Yingjia Chen +6 more
wiley +1 more source
The Development and Content Validation of the Sjögren’s Related Quality of Life Instrument (SRQoL)
Rheumatology and TherapyIntroduction Several clinical outcome assessment (COA) instruments assess Sjögren’s disease (Sjögren’s) symptoms, but do not provide comprehensive assessment of the health-related quality of life (HRQoL) impact of Sjögren’s. This study aimed to develop a
Jessica Marvel +11 more
doaj +1 more source
Chronic polydipsia and polyuria as rare renal manifestations of Sjögren's syndrome
EULAR Rheumatology Open: Sjögren's syndrome is a chronic autoimmune disorder that primarily affects the exocrine glands, with renal involvement observed in a minority of cases. We present the case of a 31-year-old woman with an 8-year history of chronic polydipsia and polyuria
Vanessa Bartsch +5 more
doaj +1 more source
Rheumatology &Autoimmunity, EarlyView.This large‐scale retrospective study of 5778 primary Sjögren's disease (SjD) patients, stratified by diagnostic age, defines a distinct clinical and immunological profile for early‐diagnosed (<45 years) disease. We identified early diagnosis as an independent risk factor for hypergammaglobulinemia and interstitial lung disease, underpinned by a ...
Yuan Ning +7 more
wiley +1 more source
Rheumatology &Autoimmunity, EarlyView.Graphical Abstract The evolving role of regulatory T cells in primary Sjögren's disease pathogenesis and the promise of Treg‐based therapies. Abstract Sjögren's disease (SjD) is a chronic systemic autoimmune disorder characterised by exocrine gland dysfunction and diverse systemic manifestations.
Gagan Urs +5 more
wiley +1 more source
A rare presentation of Sjogren\'s syndrome with ascites and liver fibrosis in a young woman: a Case report [PDF]
مجله دانشگاه علوم پزشکی بیرجندPrimary Sjogren's syndrome is a systemic autoimmune disease that encompasses a wide range of manifestations, including exocrine gland involvement and extra-glandular symptoms.
Mohammad Reza Farzaneh Far +4 more
doaj
Papular-purpuric gloves-and-socks syndrome. Presentation of a clinical case [PDF]
, 2007 Papular-Purpuric Glove-and-Sock Syndrome is a rare, infectious disease, of viral etiology, characterized by the presence of pruritus, edema and symmetrical erythema, very well defined at the wrists and ankles with a gloves-and-socks distribution.
Martínez-Sahuquillo Márquez, Ángel
core
Integrated Clinical Trial and Molecular Profiling Reveals Immune Drivers of Chronic Hand Eczema
Allergy, EarlyView.This study performed an unbiased molecular profiling of CHE patients across diverse etiologies to identify shared pathogenic drivers and evaluate the impact of IL‐4Rα blockade via dupilumab over 16 weeks. CHE shows a mixed immune signature involving type 1, 2, and 3 pathways with features of atopic dermatitis and psoriasis.
Perrine Gery +25 more
wiley +1 more source
Scientific ReportsIdentification of an early biomarker and effective testing device to differentiate dry eye disease secondary to autoimmune disease (Sjögren’s syndrome dry eye disease) from non-Sjögren’s dry eye disease are prerequisites for appropriate treatment.
Chia-Ying Tsai +7 more
doaj +1 more source