Results 111 to 120 of about 24,700 (193)

The Expression and Potential Role of MicroRNAs in Oral Lichen Planus

Journal of Oral Pathology &Medicine, EarlyView.
ABSTRACT Background Oral lichen planus (OLP) is a chronic T‐cell‐mediated immune disease of unknown aetiology. MicroRNA (miRNAs) are short non‐coding RNAs capable of regulating mRNA and may have roles in T‐cell‐related diseases. The aim of this study was to investigate the profile of miRNAs in OLP patients and its interaction with potential target ...
Mousa Ali Heba, Resteu Anastasia, Werner Andreas, Carrozzo Marco   +3 more
wiley   +1 more source

Autoimmunity and Periodontitis

Journal of Periodontal Research, EarlyView.
In a microbe‐driven inflammatory environment, peptidyl‐arginine deiminase (PAD) enzymes from neutrophils and Porphyromonas gingivalis citrullinate both microbial and self‐antigens. B cell presentation of citrullinated or self‐mimicking epitopes activates T cells that assist B cells in antibody isotype switching, affinity maturation, epitope spreading ...
Massimo Costalonga, Vivek Thumbigere‐Math, Mark C. Herzberg   +2 more
wiley   +1 more source

New Insights Into Diffuse Sclerosing Osteomyelitis: Is There a Role of ANA and Vitamin B6?

Oral Diseases, EarlyView.
ABSTRACT Object Diffuse sclerosing osteomyelitis is a poorly understood chronic disease, which appears predominantly in the mandible. Female patients are more often affected than men. DSO is an ultra‐rare disease and incidence is unknown; diagnosis can be very challenging; pathogenesis is poorly understood.
Katharina Theresa Obermeier, Tim Hildebrandt, Ina Dewenter, Wenko Smolka, Eric Hesse, Philipp Poxleitner, Sven Otto   +6 more
wiley   +1 more source

Oral Microbiome in Systemic Autoimmune Diseases: A Systematic Review

Oral Diseases, EarlyView.
ABSTRACT Objective The oral cavity represents a key but underexplored interface between host immunity and microbial communities. The aim of this systematic review was to synthesize current literature on oral microbiota alterations in systemic autoimmune diseases.
Sophie Jung, Eirini Militsi, Olivier Huck   +2 more
wiley   +1 more source

Laser Acupuncture on the Management of Xerostomia in Sjögren's Disease: A Randomized Clinical Trial

Oral Diseases, EarlyView.
ABSTRACT Objectives This study evaluated the efficacy of photobiomodulation (PBM) at acupuncture points for managing xerostomia in patients with Sjögren's Disease. Material and Methods In this randomized, double‐blind clinical trial, 50 patients were assigned to PBM group (n = 22) or sham‐PBM group (n = 28).
Matheus Ferreira Linares, Tainá Duarte dos Santos França, Maria Clara Barros Madureira Ferreira, Michele Gomes do Nascimento, Angela Luzia Branco Pinto Duarte, Luiz Alcino Gueiros   +5 more
wiley   +1 more source

Diagnostic Delay in Desquamative Gingivitis: An Observational Cohort Study

Oral Diseases, EarlyView.
ABSTRACT Objectives Non‐plaque‐induced gingivitis encompasses a heterogeneous group of conditions as defined in the 2017 Classification of Periodontal and Peri‐Implant Diseases and Conditions. Recognition is challenging and often leads to diagnostic delay.
Alessandra Caggiula, Francesca Romano, Elena Dentico, Fabiana Pinto, Maria Pia Lopez‐Jornet, Massimo Petruzzi   +5 more
wiley   +1 more source

Periodontal Disease and Salivary Gland Dysfunction in Neurofibromatosis Type 1: A Case–Control Study

Oral Diseases, EarlyView.
ABSTRACT Objectives Neurofibromatosis type 1 (NF1) presents with diverse systemic and oral manifestations. The aim of this study was to investigate the periodontal status and salivary alterations in NF1 individuals. Methods A total of 38 individuals with NF1 diagnostic criteria were compared with a control group paired by age and sex.
Eloá Borges Luna, Gustavo de Souza Vieira, Flávia Lima Kleinsorgen Motta, Ana Beatriz Oliveira Gambôa, Analúcia Rampazzo Xavier, Rafaela Elvira Rozza‐de‐Menezes, Karin Soares Cunha   +6 more
wiley   +1 more source

The role of neutrophils in the pathophysiology of inflammatory bowel diseases

Periodontology 2000, EarlyView.
Abstract Objectives Inflammatory bowel disease (IBD) encompasses a spectrum of chronic disorders of the gastrointestinal tract, with a potential bidirectional relationship with periodontitis. Neutrophils are key regulators of immune‐inflammatory responses and play a major role in both diseases.
Joao Paulo Steffens, Ekin Yay‐Kus, Rafael Scaf de Molon, Viorelia Stoica, Peter Rimmer, Josefine Hirschfeld, Asif Jilani Iqbal, Tariq Iqbal, Iain Chapple   +8 more
wiley   +1 more source

Implant therapy in older patients: Prosthetic considerations and biomechanical implications for frailty/aging

Periodontology 2000, EarlyView.
Abstract Background Population aging is reshaping prosthodontic care for both partially and completely edentulous individuals. In older adults, conditions such as frailty, comorbidities, polypharmacy, and cognitive decline can have a direct impact on the biological and biomechanical demands of implant therapy, thereby influencing the success of implant
Yu‐Ting Yeh, Lan‐Lin Chiou, Debora Yoon, Kayla Lieuw, Bryan Yang, Sabrina Maniewicz, Alkisti Zekeridou, Donald A. Curtis, Frauke Müller, Yvonne L. Hernandez‐Kapila, Guo‐Hao Lin   +10 more
wiley   +1 more source

Comparative 3‐Year Allograft Outcomes for Recipients of Kidneys From SARS‐CoV‐2 NAT‐Positive Donors

Transplant Infectious Disease, EarlyView.
In this retrospective single‐center study of 220 kidney transplants from SARS‐CoV‐2 NAT+, NAT+ with COVID as cause of death (CoV‐COD) and NATneg donors, we found no significant difference in rejection or kidney pathologies at 1 year, and death, graft loss, or eGFR at 3 years by CoV‐donor status.
Christine E. Koval, Mohamed Eltemamy, Nabin K. Shrestha, Leal Herlitz, Emilio D. Poggio, Alvin C. Wee   +5 more
wiley   +1 more source