Results 111 to 120 of about 2,901 (160)
Veterinary Ophthalmology, Volume 29, Issue 5, September 2026.ABSTRACT Objective Aqueous deficient dry eye disease (ADDE) results from a quantitative reduction in aqueous tears. We sought to determine the clinical effect of autologous mesenchymal stromal cell (MSC) injections into the region of the lacrimal gland and the gland of the third eyelid in immunomodulatory‐dependent ADDE‐affected dogs. Methods Dogs (n =
Brian C. Leonard +9 more
wiley +1 more source
ACR Open Rheumatology, Volume 8, Issue 8, August 2026.The rapid integration of immune checkpoint inhibitors (ICIs) into standard oncology protocols has birthed a new frontier in clinical rheumatology: immune‐related adverse events (irAEs). By disrupting the programmed cell death‐1 (PD‐1)/PD‐L1 and cytotoxic T‐lymphocyte‐associated protein 4 (CTLA‐4) axes to restore antitumor T cell activity, these ...
Xizi Hu +3 more
wiley +1 more source
ACR Open Rheumatology, Volume 8, Issue 8, August 2026.Objective To investigate SARS‐CoV‐2 viral shedding duration in autoimmune patients using B cell depleting (BCD) therapy or tumor necrosis factor inhibitors (TNFi) and immunocompetent comparators. Methods We conducted a matched cohort analysis among participants in POSITIVES, a prospective study enrolling outpatients with acute COVID‐19 within five days
Liya Sisay Getachew +34 more
wiley +1 more source
Advanced Science, Volume 13, Issue 45, 13 August 2026.METTL3‐mediated m6A modification stabilizes KDR/Kdr mRNA through YTHDC2, amplifying the VEGFA‐KDR feedback loop and disturbing Th17/Treg balance. This pathway promotes persistent inflammation and tissue damage in patients with AIT, and inhibiting the METTL3‐KDR axis effectively disrupts this circuit, alleviating thyroid tissue injury and disease ...
Qingyi Hu +7 more
wiley +1 more source
Overlap of Primary Biliary Cholangitis and Systemic Sclerosis: A Case of Reynolds Syndrome
Clinical Case Reports, Volume 14, Issue 8, August 2026.ABSTRACT Reynolds Syndrome should be suspected in CREST patients with persistent cholestatic liver enzymes, since delayed diagnosis allows portal hypertension and variceal bleeding to develop. Early anti‐mitochondrial antibody screening and prompt ursodeoxycholic acid therapy improve outcomes, and these patients need multidisciplinary follow‐up for ...
Ali Gohar +9 more
wiley +1 more source
Hand Lesions as a Diagnostic Clue in Unexplained SIADH
Clinical Case Reports, Volume 14, Issue 8, August 2026.Chilblain‐like hand lesions in a patient with otherwise unexplained SIADH prompted evaluation for autoimmune connective tissue disease. (A) Hand lesions before treatment. (B) Marked improvement after topical difluprednate therapy. (C) Skin biopsy showing basal liquefaction/interface change with superficial perivascular lymphocytic infiltration.
Nobuko Watanabe +8 more
wiley +1 more source
Bilateral IgG4‐Related Dacryoadenitis
Clinical Case Reports, Volume 14, Issue 8, August 2026.ABSTRACT Chronic dacryoadenitis is an uncommon inflammation of the lacrimal gland that may have various etiologies with similar presentations. IgG4‐related ophthalmic disease most often manifests as painless lacrimal gland enlargement, so the clinicians should consider IgG4‐related disease as a diagnostic possibility for dacryoadenitis.
Yan Song, Lin Ding, Tao Shen
wiley +1 more source
Multifaceted Roles of Chloroquines in Gastrointestinal Disorders and Beyond
Comprehensive Physiology, Volume 16, Issue 4, August 2026.Chloroquine (CQ) and hydroxychloroquine (HCQ) modulate lysosomal activity and autophagy, suppressing gastrointestinal inflammation and reshaping pathogenic microbiota. These mechanisms alleviate inflammatory bowel disease, inhibit associated tumor growth, and provide benefits in certain autoimmune and viral conditions.
Sihyun Jeong +3 more
wiley +1 more source
The Impact of Oral‐Gut Microbiota Structure and Its Manipulation on RA Development and Management
Food Science &Nutrition, Volume 14, Issue 8, August 2026.(A) Schematic representation of oral–gut microbiota composition in health and rheumatoid arthritis (RA), highlighting the enrichment of beneficial microorganisms (green) under healthy conditions and the expansion of pathogenic microorganisms (orange) in RA‐associated dysbiosis.
Parisa Ahmadi +8 more
wiley +1 more source
Health Science Reports, Volume 9, Issue 8, August 2026.ABSTRACT Background and Aims Human T‐cell lymphotropic virus type 1 (HTLV‐1) is a retrovirus that is associated to adult T‐cell leukemia/lymphoma (ATLL) and HTLV‐1–associated myelopathy/tropical spastic paraparesis (HAM/TSP) as two major diseases of the virus.
Arash Letafati +8 more
wiley +1 more source