Results 91 to 100 of about 37,390 (254)

Sjögren’s syndrome-associated microRNAs in CD14+ monocytes unveils targeted TGFβ signaling [PDF]

, 2016
SjS-associated miRNA expression levels are positively associated in CD14+ monocytes. Linear regression analyses were used to define associations between miRNAs in HC (circle, n = 17), SLE (triangle, n = 17), and RA (diamond, n = 18) patient groups ...
Adrienne E. G. Williams, Annie L. Chan, Carol M. Stewart, Kevin Choi, Michael R. Bubb, Seunghee Cha, Westley H. Reeves, Yun Jong Lee   +7 more
core   +4 more sources

Age‐related differences in hydroxychloroquine‐associated adverse events: A pharmacovigilance study based on the FDA Adverse Event Reporting System

British Journal of Clinical Pharmacology, EarlyView.
Aims This real‐world pharmacovigilance study utilizes FDA Adverse Event Reporting System (FAERS) data (2004–2024) to characterize age‐related disparities in hydroxychloroquine (HCQ)‐associated adverse events (AEs), addressing gaps in age‐stratified risk assessment. Methods Disproportionality analysis (reporting odds ratios, RORs) and parametric Weibull
Guanghan Sun, Jingrong Yang, Lei Wan, Xia Xu, Jing Wang   +4 more
wiley   +1 more source

EULAR Sjogren's syndrome disease activity index (ESSDAI):a user guide [PDF]

, 2015
The EULAR Sj\uf6gren's syndrome (SS) disease activity index (ESSDAI) is a systemic disease activity index that was designed to measure disease activity in patients with primary SS.
A. Tzioufas, C. Vitali, E. Theander, H. Bootsma, J.-. Gottenberg, M. Ramos-Casals, P. Brito-Zeron, P. Ravaud, R. Caporali, R. Seror, S.J. Bowman, T. Dorner, X. Mariette   +12 more
core   +2 more sources

Secretopathies emerge as a new class of neurocristopathies

Developmental Dynamics, EarlyView.
Abstract Neural crest cells are a transient embryonic population of cells that give rise to a wide range of structures, including craniofacial cartilage and bone, peripheral neurons and glia, as well as components of the cardiac outflow tract, among others.
Amanda Teixeira, Cassandra Millet‐Boureima, Joshua A. Moore, Loydie A. Jerome‐Majewska   +3 more
wiley   +1 more source

Association of Childhood Acute Leukemia With Autoimmune Diseases

International Journal of Cancer, EarlyView.
A possible link exists between various pediatric autoimmune diseases (AIDs) and increased risk of childhood leukemia. Although immune dysregulation is a key feature of these conditions, the connection between them remains unclear. In this study, using cancer registry data in Finland, the authors examined associations between AIDs and childhood acute ...
Ida Pellikka, Julia Ventelä, Anssi Auvinen, Olli Lohi, Atte Nikkilä   +4 more
wiley   +1 more source

Efficacy of Cevimeline on Xerostomia in Sjögren's Syndrome Patients: A Systematic Review and Meta-Analysis of Randomized Clinical Trials

Current Therapeutic Research
Background: Xerostomia, or dry mouth, is a common and debilitating symptom in patients with Sjögren's syndrome, affecting their quality of life. Although Cevimeline, a muscarinic agonist, has been investigated as a potential treatment, its efficacy and ...
Mehdi Karimi, MD, Fatemeh Ahmadi Hajikolaei, MD, Fahime Hoseinpour, MD, Seyed-Ali Hashemi, MD, Anita Fatehi, MD, Seyed-Abbas Pakmehr, MD, Niloofar Deravi, MD, Mahdyieh Naziri, MSc, Mohaddeseh Belbasi, MD, Sahar Khoshravesh, MD, Seyed Hossein Vaezzadeh, MD   +10 more
doaj   +1 more source

Modulation of c-Jun NH2-Terminal (JNK) by Cholinergic Autoantibodies from Patients with Sjögren’s Syndrome [PDF]

, 2011
Background: We wanted to determine (via an immunopharmacological approach) whether the c-Jun NH2 terminal kinase (JNK) cascade is phosphorylated in the submandibular gland by carbachol and cholinergic autoantibodies (IgG) present in the sera of patients ...
Borda, Enri Santiago, Passafaro, Daniela, Reina, Silvia, Sterin Borda, Leonor   +3 more
core   +1 more source

Characterizing Restorative Dental Treatments of Sjögren's Syndrome Patients Using Electronic Dental Records Data [PDF]

, 2017
Scant knowledge exists on the type of restorative treatments Sjögren's syndrome patients (SSP) receive in spite of their high dental disease burden due to hyposalivation.
Makkad, Payal, Siddiqui, Zasim, Thyvalikakath, Thankam, Wang, Yue   +3 more
core  

Analysis of SIGLEC1 as a surrogate marker for a type I interferon signature in autoimmune congenital heart block and primary Sjögren’s syndrome [PDF]

, 2019
Interferon-α (IFN-α), belonging to the family of type I interferons, is a cytokine involved in the pathogenesis of many autoimmune diseases, including systemic lupus erythematosus (SLE) and primary Sjögren’s syndrome (pSS).
Lisney, Anna
core   +1 more source

Characterization of Pulmonary Functional Abnormalities in Systemic Sclerosis Using Xenon MRI

Journal of Magnetic Resonance Imaging, EarlyView.
ABSTRACT Background Xenon MRI is increasingly used to evaluate patients with interstitial lung disease (ILD) and pulmonary hypertension (PH), both of which are common manifestations of systemic sclerosis (SSc). As such, Xe‐MRI may be suited to interrogate lung function impairment in SSc.
Dawson Shaver, Steven Haworth, Evan Graumann, Bradie Frizzell, David H. Lee, Jiwoong Choi, Chase S. Hall, Scott M. Matson, Mark Hamblin, Mario Castro, Paul S. Schmidt, Peter J. Niedbalski   +11 more
wiley   +1 more source