Clinical features of Sjögren’s syndrome patients with autoantibodies against interferons
Clinical and Translational Medicine, 2019 Background Sjögren’s syndrome (SS) is an autoimmune disease characterized by immune attack on the salivary and lacrimal glands. Given the known cytokine activation and type I interferon gene expression signature found in SS, we hypothesized that ...
Peter D. Burbelo +4 more
doaj +1 more source
Unilateral Trigeminal Sensory Neuropathy with Sjögren’s Syndrome with Liver and Renal Impairment
Neurology International, 2021 Liver and renal involvement is a rare event in Sjögren’s syndrome. Sjögren’s syndrome is characterized by the progressive immune-mediated destruction of epithelial tissues of the salivary and lacrimal glands.
Kana Ozasa +3 more
doaj +1 more source
Antigen-driven clonal proliferation of B cells within the target tissue of an autoimmune disease: the salivary glands of patients with Sjögren's syndrome [PDF]
, 1998 Structures resembling germinal centers are seen in the salivary glands of patients with Sjögren's syndrome, but it is not known whether the microenvironment of these cell clusters is sufficient for the induction of a germinal center response.
Berek, C. +4 more
core +2 more sources
European Medical Journal, 2020 This case details a 33-year-old female who presented with a suggestive autoimmune history, arthralgias, and splenomegaly, and tested positive for Sjögren’s syndrome and anti-liver–kidney microsomal antibody.
Muhammad Sohaib Asghar +5 more
doaj +1 more source
Developing a service user informed intervention to improve participation and ability to perform daily activities in primary Sjögren’s syndrome: a mixed-methods study protocol [PDF]
, 2014 Introduction: A significant proportion of patients with primary Sjögren’s syndrome (PSS) is functionally impaired and experience difficulties participating in various aspects of everyday life.
Anderson +32 more
core +1 more source
Audio-vestibular symptoms in systemic autoimmune diseases [PDF]
, 2018 Immune-mediated inner ear disease can be primary, when the autoimmune response is against the inner ear, or secondary. The latter is characterized by the involvement of the ear in the presence of systemic autoimmune conditions. Sensorineural hearing loss
Adelchi, Croce +7 more
core +1 more source
Analysis of the pathogenic factors and management of dry eye in ocular surface disorders [PDF]
, 2017 The tear film represents the interface between the eye and the environment. The alteration of the delicate balance that regulates the secretion and distribution of the tear film determines the dry eye (DE) syndrome. Despite having a multifactorial origin,
Albietz +14 more
core +1 more source
A case with acquired lacrimal fistula due to Sjögren's syndrome
American Journal of Ophthalmology Case Reports, 2019 Purpose: To report a case with lacrimal fistula presumably associated with Sjögren's syndrome. Observations: A patient with Sjögren's syndrome was referred to our hospital for fistula from the inferior lacrimal canaliculus to the palpebral conjunctiva of
Sho Ishikawa +3 more
doaj +1 more source
BMC Nephrology, 2012 Background Sjögren’s syndrome is a systemic autoimmune disease in which lymphatic cells destroy the salivary and lacrimal glands. Glomerulonephritis is thought to be a rare occurrence in primary Sjögren’s syndrome.
Kim Chang +5 more
doaj +1 more source
Neuro-Sjögren: Peripheral Neuropathy With Limb Weakness in Sjögren's Syndrome
Frontiers in Immunology, 2019 Objective: Sjögren's syndrome is a heterogeneous inflammatory disorder frequently involving peripheral nerves with a wide spectrum of sensory modalities and distribution patterns.
Tabea Seeliger +10 more
doaj +1 more source