Results 61 to 70 of about 2,901 (160)

Exocrine Gland Dysfunction in Parkinson's Disease: Pathophysiology, Clinical Manifestations, and Therapeutic Perspectives—A Narrative Review

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Non‐motor symptoms, especially autonomic dysfunction, are major contributors to disability and decreased quality of life in Parkinson's disease (PD). Despite being common and having a wide range of clinical facets, exocrine gland dysfunction is still not well recognized and managed.
Renato P. Munhoz, Marina Farah, Laura Silveira‐Moriyama   +2 more
wiley   +1 more source

Age‐related clinical heterogeneity and peripheral T cell profile alterations in primary Sjögren's disease: A retrospective study of 5778 patients

Rheumatology &Autoimmunity, EarlyView.
This large‐scale retrospective study of 5778 primary Sjögren's disease (SjD) patients, stratified by diagnostic age, defines a distinct clinical and immunological profile for early‐diagnosed (<45 years) disease. We identified early diagnosis as an independent risk factor for hypergammaglobulinemia and interstitial lung disease, underpinned by a ...
Yuan Ning, Ruiling Feng, Kai Zhang, Yipeng Han, Ruoyi Wang, Guangwen Li, Yuebo Jin, Jing He   +7 more
wiley   +1 more source

Pregnancy in CTD‐interstitial lung disease: Current evidence, clinical challenges, and a proposed management algorithm

Rheumatology &Autoimmunity, EarlyView.
Summary of pregnancy management in CTD‐ILD across preconception, antenatal, and postpartum phases, emphasizing risk stratification and multidisciplinary care. 6MWT, 6‐min walk test; CTD‐ILD: connective tissue disease‐interstitial lung disease; DLCO, diffusion capacity of the lung for carbon monoxide; FVC, forced vital capacity; MDT, multidisciplinary ...
Khaled Aldhuaina, Ghaydaa Aldabie, Mohammad Abdulsalam, Ali Jawad   +3 more
wiley   +1 more source

Sjögren's syndrome concurrent with protein‐losing gastroenteropathy with secondary systemic capillary leak syndrome : A case report

Clinical Case Reports, 2018
Key Clinical Message Sjögren's syndrome concurrent with protein‐losing gastroenteropathy can develop into secondary systemic capillary leak syndrome.
Kei Watanabe, Shinichiro Murakami, Masahiro Misago, Mai Yoshikawa, Daisuke Tamai, Shinichiro Nakao, Takato Ueoka, Mototoshi Ito, Yasuhisa Shinomura, Nobuyuki Kajiwara   +9 more
doaj   +1 more source

Salivary transforming growth factor alpha in patients with Sjögren's syndrome and reflux laryngitis

Brazilian Journal of Otorhinolaryngology, 2014
Introduction: Saliva plays a key role in the homeostasis of the digestive tract, through its inorganic components and its protein growth factors.
Marco Antonio dos Anjos Corvo, Claudia Alessandra Eckley, Luis Vicente Rizzo, Luiz Roberto Sardinha, Tomas Navarro Rodriguez, Ivo Bussoloti Filho   +5 more
doaj   +1 more source

Dry eye disease symptoms and associated risk factors in a Norwegian clinical cohort

Acta Ophthalmologica, EarlyView.
Abstract Background The relationship between dry eye disease (DED) symptoms and different demographic, clinical and lifestyle factors remains poorly understood. Norway's cold climate and dry indoor air may accelerate tear evaporation, contributing to a very high meibomian gland dysfunction prevalence, as found in multiple studies.
Mazyar Yazdani, Fredrik A. Fineide, Reza A. Badian, Ayyad Zartasht Khan, Helge Rootwelt, Jan Terje Kvaløy, Tor Paaske Utheim   +6 more
wiley   +1 more source

Labial salivary gland biopsy: a crucial method for confirming seronegative Sjogren’s syndrome—a case report

Bulletin of the National Research Centre
Background Sjogren’s syndrome is an autoimmune disease that affects exocrine glands like sweat glands, salivary glands, and lacrimal glands. Dentists frequently encounter these patients and have an important role in establishing the diagnosis.
Satyasai S. G. Romala, Kishore Moturi, Ravikanth Manyam, Meghana Vadupu, P. Divya Naga Lakshmi, Anil Budumuru, U. Shivajiraju, J. S. D. N. Sai Hyma, R. V. S. N. S. Ramachandrudu   +8 more
doaj   +1 more source

Primary Sjögren’s syndrome with polymyositis, a rare amalgamation

Egyptian Rheumatology and Rehabilitation, 2018
Sjögren’s syndrome is characterized by diminished lacrimal and salivary gland secretory function. This disorder is not strictly confined to the exocrine glands and its manifestations may extend to extraglandular sites, such as the lungs, kidneys ...
Harpreet Singh, Deepak Jain, B Kiran, Neeraj Kumar   +3 more
doaj   +1 more source

Maternal and Peri/Neonatal Mortality and Morbidity in Midwife‐Assisted Low‐Risk Birth Outside Hospital Compared to Obstetric Team‐Assisted Low‐Risk Hospital Birth: A Systematic Review and Meta‐Analysis

Acta Paediatrica, EarlyView.
ABSTRACT Aim To compare outcomes of planned home or freestanding midwifery unit (FMU) with obstetric unit births in high‐income countries. Methods We conducted a systematic review and meta‐analysis of systematic reviews, randomised controlled trials, cohort studies, case series, and case reports.
Carolina Herding, Ulla‐Britt Wennerholm, Anders Elfvin, Sara Holm, Karolina Linden, Jahangir Khan, Max Petzold, Christina Bergh, Petteri Sjögren, Ida Stadig, Ann Liljegren, Ylva Carlsson, Verena Sengpiel   +12 more
wiley   +1 more source

Phenotype‐specific immune profiles and outcomes in childhood autoimmune neutropenia: A 20‐year cohort study

British Journal of Haematology, EarlyView.
Summary Childhood autoimmune neutropenia (AIN) encompasses heterogeneous entities; phenotype‐specific immunological profiles and their relationship to infection outcomes remain incompletely defined. To characterise clinical, immunological and long‐term outcomes across distinct phenotypes of childhood AIN.
Ioanna Saougou, Chrysoula Kosmeri, Nikolaos Chaliasos, Irene Mavroudi, Charalampos Pontikoglou, Alexandros Makis   +5 more
wiley   +1 more source