Results 11 to 20 of about 107,264 (291)
Selective polyclonal increase of immunoglobulin G1 subclass: a link with Sjögren's syndrome. [PDF]
Annals of the Rheumatic Diseases, 1990 A selective polyclonal increase in IgG1 has been described previously in a group of patients with connective tissue disease; nine of the 16 patients had a prior diagnosis of systemic lupus erythematosus (SLE). A detailed clinical and serological study of 32 patients with this immunoglobulin abnormality has now been made.
Hay, E +5 more
openaire +3 more sources
Epistasis between the MHC and the RCAα block in primary Sjögren syndrome [PDF]
Annals of the Rheumatic Diseases, 2008 The RCA alpha block (Regulators of Complement Activation, 1q32) contains critical complement regulatory genes such as CR1 and MCP. This study examined RCA alpha block haplotype associations with both disease susceptibility and diversification of the anti-Ro/La autoantibody response in primary Sjögren syndrome (pSS).115 patients with pSS and 98 controls
Lester, S +5 more
openaire +2 more sources
The importance of minor salivary gland biopsy in sjögren syndrome diagnosis and the clinicopathological correlation [PDF]
Turkish Journal of Pathology, 2016 Minor salivary gland biopsy is one of the objective tests used in the diagnosis of Sjögren syndrome. The aim of our study was to compare the clinical and laboratory data of primary and secondary Sjögren syndrome cases with a lymphocyte score 3 and 4 in the minor salivary gland biopsy.Data from a total of 2346 consecutive minor salivary gland biopsies ...
Serin, Gurdeniz +4 more
openaire +5 more sources
Sjögren’s syndrome with and without neurological involvement
Journal of Neurology, 2023 Objective Neurological manifestations of Sjögren’s syndrome can be severe but also treatment-responsive. We aimed to systematically evaluate neurological manifestations of primary Sjögren’s syndrome and find clinical features allowing sufficient ...
T. Seeliger +9 more
semanticscholar +1 more source
Epidemiology of Sjögren’s: A Systematic Literature Review
Rheumatology and Therapy, 2023 Primary Sjögren’s is a multi-system autoimmune disease affecting patients’ physical, mental, and emotional wellbeing. The epidemiology of Sjögren’s is not well understood, and up-to-date epidemiological evidence is needed to improve knowledge and ...
Eleanor Thurtle +5 more
semanticscholar +1 more source
BMC Rheumatology, 2023 Background Dry eyes and mouth are symptoms of Sjogren syndrome, which can occur on its own and be referred to as primary Sjogren syndrome or in conjunction with other rheumatic diseases like rheumatoid arthritis and be referred to as secondary Sjogren ...
Hagar Elsayed Fakher +3 more
doaj +1 more source
A new molecular classification to drive precision treatment strategies in primary Sjögren’s syndrome
Nature Communications, 2021 There is currently no approved treatment for primary Sjögren’s syndrome, a disease that primarily affects adult women. The difficulty in developing effective therapies is -in part- because of the heterogeneity in the clinical manifestation and ...
Perrine Soret +123 more
semanticscholar +1 more source
Annals of the Rheumatic Diseases, 2022 Objective To develop a composite responder index in primary Sjögren’s syndrome (pSS): the Sjögren’s Tool for Assessing Response (STAR). Methods To develop STAR, the NECESSITY (New clinical endpoints in primary Sjögren’s syndrome: an interventional trial ...
R. Seror +15 more
semanticscholar +1 more source
Sjögren syndrome hidden by previous parotidectomy and cervicofacial radiotherapy
Journal of Oral Medicine and Oral Surgery, 2018 Introduction: Sjögren’s syndrome (SS) is a chronic inflammatory auto-immune disease of the exocrine glands which incidence increases with age. Sex ratio is 9.9 female for 1 male.
Desoutter Aline +2 more
doaj +1 more source
Autoimmune diseases and their manifestations on oral cavity: diagnosis and clinical management [PDF]
, 2018 Oral signs are frequently the first manifestation of autoimmune diseases. For this reason, dentists play an important role in the detection of emerging autoimmune pathologies.
Bossù, Maurizio +5 more
core +2 more sources