Results 91 to 100 of about 19,520 (233)
Acta Ophthalmologica, EarlyView.Abstract Purpose Immune checkpoint inhibitors (ICIs) have transformed cancer therapy but may cause immune‐related adverse events (irAEs), including dry eye disease (DED). This study aimed to quantify the incidence of ICI‐associated DED and to evaluate factors contributing to variability across studies.
Kai‐Yang Chen +2 more
wiley +1 more source
Sjögren-Larsson syndrome: report of monozygote twins and a case with a novel mutation
The Turkish Journal of Pediatrics, 2012 Sjögren-Larsson syndrome is an autosomal recessive neurocutaneous disease caused by mutations in the ALDH3A2 gene for fatty aldehyde dehydrogenase, a microsomal enzyme that catalyzes the oxidation of medium- and long-chain aliphatic aldehydes ...
Uluç Yiş, Allesandro Terrinoni
doaj
The impact of systemic long‐term medications for the development of age‐related macular degeneration
Acta Ophthalmologica, EarlyView.Abstract Purpose Age‐related macular degeneration (AMD) is a leading cause of central vision loss in the elderly; however, the systemic factors that modulate its incidence and progression remain unclear. We sought to determine whether long‐term use of systemic medications, including diabetes and antithrombotic medications, corticosteroids and ...
Hanna Heloterä +3 more
wiley +1 more source
, 2018 Ultrasonography has become a valuable tool for the assessment of salivary gland involvement in Sjögren syndrome. Diagnostic pitfalls can be encountered in late stages of the disease, in which morphologic changes may overlap with other pathologies of the ...
Diana Girnita +5 more
core +1 more source
Dry eye disease symptoms and associated risk factors in a Norwegian clinical cohort
Acta Ophthalmologica, EarlyView.Abstract Background The relationship between dry eye disease (DED) symptoms and different demographic, clinical and lifestyle factors remains poorly understood. Norway's cold climate and dry indoor air may accelerate tear evaporation, contributing to a very high meibomian gland dysfunction prevalence, as found in multiple studies.
Mazyar Yazdani +6 more
wiley +1 more source
British Journal of Haematology, EarlyView.Summary Childhood autoimmune neutropenia (AIN) encompasses heterogeneous entities; phenotype‐specific immunological profiles and their relationship to infection outcomes remain incompletely defined. To characterise clinical, immunological and long‐term outcomes across distinct phenotypes of childhood AIN.
Ioanna Saougou +5 more
wiley +1 more source
Is Sjögren's syndrome a retroviral disease?
, 2011 Circumstantial evidence suggests that retroviruses play a role in the pathogenesis of Sjögren's syndrome. Such evidence, derived from studies of patients with Sjögren's syndrome, includes the following: the presence of serum antibodies cross ...
Gamaletsou, M.N. +2 more
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Diagnosis and management of neutropenia in adults: Expert guidance
British Journal of Haematology, EarlyView.Severe neutropenia can result from decreased production of neutrophil precursors in the bone marrow, as in the case of severe congenital neutropenia, or from increased utilization of neutrophils or their accelerated destruction as for drug‐induced neutropenia or autoimmune neutropenia. Severe chronic neutropenia increases susceptibility to bacterial or
Karl Welte +5 more
wiley +1 more source
Cell Proliferation, EarlyView.This study elucidates a novel Kupffer cell‐neutrophil‐hepatocyte axis that drives metabolic‐immune crosstalk during acute liver failure. Specifically, lactate‐primed NETs release links metabolic reprogramming to NETosis‐induced regenerative failure in hepatocytes via the TLR9/KLF15/AJUBA axis.
Jin Guo +5 more
wiley +1 more source
Sjögren\u27s Syndrome In Childhood: Report of a Case
, 1969 This report documents a rare case of Sjögren\u27s Syndrome which began in a child with juvenile rheumatoid arthritis at the age 10 years, followed by the symptoms of xerostomia with intermittent salivary gland swelling 15 months later.
Duncan, Howard +2 more
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