Results 81 to 90 of about 19,520 (233)

Exocrine Gland Dysfunction in Parkinson's Disease: Pathophysiology, Clinical Manifestations, and Therapeutic Perspectives—A Narrative Review

open access: yesMovement Disorders Clinical Practice, EarlyView.
Abstract Background Non‐motor symptoms, especially autonomic dysfunction, are major contributors to disability and decreased quality of life in Parkinson's disease (PD). Despite being common and having a wide range of clinical facets, exocrine gland dysfunction is still not well recognized and managed.
Renato P. Munhoz   +2 more
wiley   +1 more source

Lymphoproliferation in autoimmunity and Sjögren's syndrome.

open access: yes, 2003
Sjögren's syndrome is a chronic inflammatory process involving primarily the exocrine glands. Its association with lymphoma is well documented.
Moutsopoulos, H.M., Voulgarelis, M.
core  

Age‐related clinical heterogeneity and peripheral T cell profile alterations in primary Sjögren's disease: A retrospective study of 5778 patients

open access: yesRheumatology &Autoimmunity, EarlyView.
This large‐scale retrospective study of 5778 primary Sjögren's disease (SjD) patients, stratified by diagnostic age, defines a distinct clinical and immunological profile for early‐diagnosed (<45 years) disease. We identified early diagnosis as an independent risk factor for hypergammaglobulinemia and interstitial lung disease, underpinned by a ...
Yuan Ning   +7 more
wiley   +1 more source

Les complications systémiques de la maladie de Sjögren (ou syndrome de Sjögren primitif)

open access: yes, 2022
National audiencePrimary Sjögren syndrome (pSS) is a progressive autoimmune disease characterized by sicca and systemic manifestations that are frequent and potentially severe, especially when related to B cell activity or the presence of ...
Tison, Alice   +1 more
core   +1 more source

Integrated Clinical Trial and Molecular Profiling Reveals Immune Drivers of Chronic Hand Eczema

open access: yesAllergy, EarlyView.
This study performed an unbiased molecular profiling of CHE patients across diverse etiologies to identify shared pathogenic drivers and evaluate the impact of IL‐4Rα blockade via dupilumab over 16 weeks. CHE shows a mixed immune signature involving type 1, 2, and 3 pathways with features of atopic dermatitis and psoriasis.
Perrine Gery   +25 more
wiley   +1 more source

Primary Sjögren’s syndrome related optic neuritis

open access: yesInternational Journal of Ophthalmology, 2013
AIM:To determine the clinical features, diagnosis and treatment of the primary Sjögren syndrome (SS) related optic neuritis.METHODS:The clinical data of 8 patients (12 eyes) with primary SS related optic neuritis were analyzed retrospectively.RESULTS ...
Wei-Qiang Tang, Shi-Hui Wei
doaj   +1 more source

Association between systemic activity ındex and dry eye severity in patients with primary Sjögren syndrome

open access: yes, 2018
Purpose: The aim of the present study was to compare the severity of ocular and systemic findings among patients with primary Sjögren syndrome. Methods: The study followed a prospective controlled design and comprised two groups; the test group ...
Dilay Ozek (5835836)   +2 more
core   +2 more sources

Can universal cervical length screening with vaginal progesterone for a short cervix reduce preterm birth? A systematic review and meta‐analyses

open access: yesActa Obstetricia et Gynecologica Scandinavica, EarlyView.
Preterm birth is associated with substantial neonatal morbidity and mortality. We evaluated whether universal cervical length screening with ultrasound, followed by progesterone therapy for women with a short cervix, has the potential to reduce the incidence of preterm birth.
Mira Zethelius   +11 more
wiley   +1 more source

Sjögren's syndrome: Autoimmune epithelitis

open access: yes, 1999
Sjögren's syndrome is a chronic autoimmune disorder characterized by mononuclear cell infiltration proximally to epithelial cells of exocrine glands.
Tzioufas, A.G.   +3 more
core  

Anthropometric and biochemical variables among Sjögren syndrome.

open access: yes, 2015
Data were shown as mean±SDAbbreviation: BMI: body mass index; WBC: white cell count; Hb: hemogloblin; Gas6: growth-arrest specific protein 6; ND: no done; NA: no applicable; ns: not significantAnthropometric and biochemical variables among Sjögren ...
Chi-Ching Chang (804445)   +7 more
core   +1 more source

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