Results 61 to 70 of about 31,438 (223)

Assessing the determination of salivary electrolytes and anti-Ro and anti-La antibodies for the diagnosis of Sjogren s syndrome (SS) [PDF]

open access: yes, 2010
The aim of this study was to assess changes in salivary electrolyte flow and composition and the presence of anti-Ro/SSA and anti-La/SSB serum and saliva antibodies and their implications for the non-invasive diagnosis of SS. Study design: 73 patients
Albiero, Eduardo   +7 more
core   +1 more source

Mendelian Randomization and Double Machine Learning Modeling Reveal Brain Imaging‐Derived Phenotypes as Functional Contributors to 18 Autoimmune Inflammatory Diseases

open access: yesAdvanced Science, EarlyView.
This schematic integrates the eight statistically significant causal relationships identified between 1,366 brain imaging‐derived phenotypes (IDPs) and 18 autoimmune inflammatory diseases (AIDs). Arrows indicate the direction of causality inferred from bidirectional two‐sample MR analyses.
Jinbin Chen   +8 more
wiley   +1 more source

Insights into the molecular mechanism of Sjogren's syndrome [PDF]

open access: yes, 2017
Sjogren’s syndrome (SS) is a chronic autoimmune disease, that affects primarily salivary and lacrimal glands, leading to increased morbidity. Recent studies indicate that loss of salivary gland function is associated with defective cell polarity ...
Langara, Hans A.
core  

Macrophage TRIM21 Inhibition Ameliorates Murine Acute Pancreatitis via PHB2‐Mediated Mitochondrial Stabilization

open access: yesAdvanced Science, EarlyView.
Macrophage‐derived TRIM21 drives the progression of AP via ubiquitin‐proteasome‐mediated degradation of PHB2, leading to impaired PHB2‐mediated mitophagy. Therefore, accumulation of cytosolic mtDNA hyperactivates the cGAS‐STING signaling axis, thereby amplifying inflammatory cascades.
Yansong Xu   +7 more
wiley   +1 more source

New Aspects of Thromboangiitis obliterans (von Winiwarter-Buerger's Disease) [PDF]

open access: yes, 1984
The existence of thromboangiitis obliterans as a clinical entity has been a matter of debate for many years. In contrast to other immunovasculitides there is no organ involvement while peripheral vessels are affected.
Berlit, Peter   +3 more
core   +1 more source

Cytokine‐Engineered Chimeric Antigen Receptor‐T Cell Therapy: How to Balance the Efficacy and Toxicity

open access: yesAdvanced Science, EarlyView.
Cytokine‐engineered CAR‐T cells represent a promising immunotherapy against malignancies due to direct tumor killing and potent immunity response. However, significant toxicities, including CRS and ICANS, have restricted clinical applications. How to keep the risk‐benefit balance of the advanced therapy is of great importance for maximizing the benefit
Xinru Zhang   +7 more
wiley   +1 more source

Sjögren Syndrome Which Simulates Relapsing Remitting Multiple Sclerosis Clinical Features: Case Report

open access: yesTürk Nöroloji Dergisi, 2013
Sjögren syndrome (SS) is a chronic, inflammatory, autoimmune disease. It emerges as a dry mouth and eyes (sicca symptoms) because, it fundamentally affects exocrine glands, frequently, salivary gland and lachrymal gland.
Haluk Gümüş, Zehra Akpınar
doaj   +1 more source

Computed tomographic imaging characteristics of the normal canine lacrimal glands. [PDF]

open access: yes, 2014
BackgroundThe canine lacrimal gland (LG) and accessory lacrimal gland of the third eyelid (TEG) are responsible for production of the aqueous portion of the precorneal tear film.
Murphy, Christopher J   +2 more
core   +2 more sources

Extracellular Vesicles in Autoimmune Diseases: From Diagnostic Biomarkers to Engineered Therapeutics

open access: yesAdvanced Science, EarlyView.
This review provides a systematic comparison of extracellular vesicles (EVs) from both mammalian and plant sources in the context of autoimmune diseases. It highlights their emerging roles as precision biomarkers and engineered therapeutic platforms.
Yufei Wu   +6 more
wiley   +1 more source

Effect of sialagogue on bleeding on probing in Sjögren′s syndrome

open access: yesIndian Journal of Dental Research, 2013
Background: Bleeding on probing (BOP) is a frequent observation in patients with Sjögren′s syndrome and a sialagogue is routinely prescribed for these patients.
Medha Singh, Athena Papas
doaj   +1 more source

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