Results 81 to 90 of about 31,438 (223)

Fatty aldehyde dehydrogenase, the enzyme downstream of tetrahydrobiopterin-dependent alkylglycerol monooxygenase

Pteridines, 2013
The tetrahydrobiopterin-dependent degradation of ether lipids by alkylglycerol monooxygenase (AGMO) produces fatty aldehydes, which are toxic to cells.
Keller Markus A., Watschinger Katrin, Golderer Georg, Werner-Felmayer Gabriele, Werner Ernst R.   +4 more
doaj   +1 more source

Sjogren′s syndrome

Journal of Indian Academy of Oral Medicine and Radiology, 2008
Sjogren′s syndrome (SS) is a chronic autoimmune disorder. It is characterized by dysfunction and destruction of exocrine glands associated with lymphocytic infiltrates and immunological hyperactivity.
Ankur Jethlia, Vaishali Keluskar, Arvind Shetti   +2 more
doaj   +1 more source

Dry eye: etiopathogenesis and treatment [PDF]

, 2010
Olho seco é uma doença multifatorial das lágrimas e da superfície ocular que resulta em desconforto, distúrbios visuais e instabilidade do filme lacrimal.
ARRUDA, Gustavo Viani, FONSECA, Ellen Carrara, ROCHA, Eduardo Melani   +2 more
core   +2 more sources

A Randomized, Placebo‐Controlled Trial of Hydroxychloroquine in Incomplete Lupus

Arthritis &Rheumatology, EarlyView.
Objective Patients with features of systemic lupus erythematosus (SLE) who do not fulfill classification criteria can be designated as incomplete lupus erythematosus (ILE). This condition includes individuals with a high risk of progression to SLE. Treatment of ILE may reduce symptoms, severity, and incidence of SLE.
Nancy J. Olsen, Duanping Liao, Judith A. James, Joel M. Guthridge, Cristina Arriens, Diane Kamen, Mariko Ishimori, Daniel J. Wallace, Christopher Striebich, Sonali Narain, Benjamin F. Chong, Fan He, Eric W. Schaefer, Vernon M. Chinchilli, David R. Karp   +14 more
wiley   +1 more source

Sjögren Disease—B Cells at the Brink: From Autoimmunity to Lymphomagenesis and the Rise of Novel B Cell–Targeted Therapies

Arthritis &Rheumatology, EarlyView.
Sjögren disease (SjD) is a common systemic autoimmune disorder characterized by inflammation of the exocrine glands, resulting in dryness. Patients frequently exhibit extraglandular manifestations affecting various organ systems. To date, there are no US Food and Drug Administration (FDA)‐approved disease‐modifying therapies for SjD. In this review, we
Rachael A. Gordon, Sara S. McCoy
wiley   +1 more source

Síndrome de Sjögren Sjögren syndrome

Revista Cubana de Medicina, 2010
Se realiza una revisión de las bases de datos a las que se puede acceder a través de Internet sobre temas de medicina, así como de las principales revistas y sitios que tratan sobre afecciones reumatológicas buscando los conceptos más actuales que se ...
José Pedro Martínez Larrarte, Yusimí Reyes Pineda   +1 more
doaj  

Cranial Nerve Mononeuritis as Neurological Sign of Primary Sjögren Syndrome: A Case Report [PDF]

Düşünen Adam Psikiyatri ve Nörolojik Bilimler Dergisi, 2005
Primary Sjögren syndrome is a relatively common auto-immune disease. It may cause different neurological signs by the involvement of central and peripheric nervous systems.
Göksel Somay, Pınar Topaloğlu, Gülistan Uşak Halaç, Özlem Araal, Nuri Y. Erenoğlu   +4 more
doaj  

Primary Sjogren’s syndrome manifesting as recurrent hypokalemia with distal renal tubular acidosis

Sri Lanka Journal of Medicine, 2020
Sjogren’s syndrome is an autoimmune disease with both glandular and extraglandular manifestations.   We report a rare case of primary Sjogren syndrome without sicca symptoms presenting with renal tubular acidosis and recurrent hypokalaemia.
Ajeya Kashyap, Siddharth Gosavi, Sharath Savanth, Sudha Rani Mehta   +3 more
doaj   +1 more source

Clinical and laboratorial profile and histological features on minor salivary glands from patients under investigation for Sjögren's syndrome [PDF]

, 2014
Diagnosis of Sjögren's syndrome (SS) is complex and the usefulness of labial minor salivary glands biopsy in this process remains controversial. Objectives: to evaluate the clinical and laboratorial profile and histological features on labial minor ...
dos-Santos, Teresa-Cristina-Ribeiro-Bartholomeu, Pereira, Débora-Lima, Pires, Fábio-Ramôa, Vilela, Verônica-Silva   +3 more
core   +1 more source

Biomarkers of Lupus Nephritis Histopathology: Where Do We Stand?

Arthritis &Rheumatology, EarlyView.
Objective Lupus nephritis (LN) is characterized by a variable disease course, necessitating continuous monitoring. There is an urgent need to identify noninvasive biomarkers. By reviewing and critically assessing the quality of existing studies on LN biomarkers correlating with histopathology, we here explore the challenges in promoting their use in ...
Valentina Querin, Leonardo Palazzo, Agnes B. Fogo, Mark Haas, David R. W. Jayne, Liz Lightstone, Brad H. Rovin, Surya V. Seshan, Augusto Vaglio, Ioannis Parodis, Ingeborg M. Bajema, for the Lupus Nephritis Classification Steering Committee   +11 more
wiley   +1 more source