Results 131 to 140 of about 18,863 (224)

Targeting METTL3 Attenuates Thyroid Inflammatory Injury by Restoring Th17/Treg Balance through a YTHDC2‐m6A‐Dependent KDR/VEGFA Loop

Advanced Science, Volume 13, Issue 45, 13 August 2026.
METTL3‐mediated m6A modification stabilizes KDR/Kdr mRNA through YTHDC2, amplifying the VEGFA‐KDR feedback loop and disturbing Th17/Treg balance. This pathway promotes persistent inflammation and tissue damage in patients with AIT, and inhibiting the METTL3‐KDR axis effectively disrupts this circuit, alleviating thyroid tissue injury and disease ...
Qingyi Hu, Huan Liu, Anwen Ren, Zimei Tang, Jie Tan, Wen Yang, Jie Ming, Tao Huang   +7 more
wiley   +1 more source

Shared gene signatures between rheumatoid arthritis and Sjögren's syndrome. [PDF]

Am J Clin Exp Immunol
Li YF, Gao ZW, Liu L, Wang X, Fan K, Lin F, Hei RX.   +6 more
europepmc   +1 more source

Overlap of Primary Biliary Cholangitis and Systemic Sclerosis: A Case of Reynolds Syndrome

Clinical Case Reports, Volume 14, Issue 8, August 2026.
ABSTRACT Reynolds Syndrome should be suspected in CREST patients with persistent cholestatic liver enzymes, since delayed diagnosis allows portal hypertension and variceal bleeding to develop. Early anti‐mitochondrial antibody screening and prompt ursodeoxycholic acid therapy improve outcomes, and these patients need multidisciplinary follow‐up for ...
Ali Gohar, Ira Abid, Syeda Eman Fatima, Abdum Muneeb Sandhu, Zain Fatima, Humayun Nasir, Fatima Arshad, Abdul Rehman Shahid Khan, Muhammad Husnain Ahmad, Masab Ali   +9 more
wiley   +1 more source

Educational Case: Connective tissue disorders: Sjögren's syndrome. [PDF]

Acad Pathol
Patterson AS, Robbins QC, Knollmann-Ritschel B.   +2 more
europepmc   +1 more source

Hand Lesions as a Diagnostic Clue in Unexplained SIADH

Clinical Case Reports, Volume 14, Issue 8, August 2026.
Chilblain‐like hand lesions in a patient with otherwise unexplained SIADH prompted evaluation for autoimmune connective tissue disease. (A) Hand lesions before treatment. (B) Marked improvement after topical difluprednate therapy. (C) Skin biopsy showing basal liquefaction/interface change with superficial perivascular lymphocytic infiltration.
Nobuko Watanabe, Takuya Omura, Takahiro Kamihara, Taiki Sugimoto, Jun Matsumoto, Tomomi Omura, Masaki Hasegawa, Mariko Shimono, Zenzo Isogai   +8 more
wiley   +1 more source

The 2D:4D Digit Ratio and Primary Sjögren's Syndrome: A Window Into Prenatal Hormonal Influences on Exocrine Autoimmunity. [PDF]

Am J Hum Biol
Gür M, Akkoc RF, Oz B, Karatas A, Koca SS.   +4 more
europepmc   +1 more source

Bilateral IgG4‐Related Dacryoadenitis

Clinical Case Reports, Volume 14, Issue 8, August 2026.
ABSTRACT Chronic dacryoadenitis is an uncommon inflammation of the lacrimal gland that may have various etiologies with similar presentations. IgG4‐related ophthalmic disease most often manifests as painless lacrimal gland enlargement, so the clinicians should consider IgG4‐related disease as a diagnostic possibility for dacryoadenitis.
Yan Song, Lin Ding, Tao Shen
wiley   +1 more source

Causal associations between Sjögren's syndrome and subtypes of endometrial cancer. [PDF]

BMC Immunol
Zhu Y, Wu Q, Hu L, Wang L.
europepmc   +1 more source

Multifaceted Roles of Chloroquines in Gastrointestinal Disorders and Beyond

Comprehensive Physiology, Volume 16, Issue 4, August 2026.
Chloroquine (CQ) and hydroxychloroquine (HCQ) modulate lysosomal activity and autophagy, suppressing gastrointestinal inflammation and reshaping pathogenic microbiota. These mechanisms alleviate inflammatory bowel disease, inhibit associated tumor growth, and provide benefits in certain autoimmune and viral conditions.
Sihyun Jeong, Eunsoo Kim, Yong Sung Kim, Eunok Im   +3 more
wiley   +1 more source

Distal Renal Tubular Acidosis as a Renal Manifestation of Sjögren's Syndrome: A Case Report. [PDF]

Cureus
Sharma S, Khalid A, Herrera GA, Al Jaber E.   +3 more
europepmc   +1 more source