Results 161 to 170 of about 18,863 (224)

Haemostatic changes and bleeding with anti‐IL‐6 directed therapy in autoimmune diseases

British Journal of Pharmacology, Volume 183, Issue 15, Page 4111-4125, August 2026.
Abstract Anti‐IL‐6 directed therapy, especially tocilizumab (TCZ), is widely used for the treatment of autoimmune diseases such as rheumatoid arthritis, giant cell arteritis and systemic juvenile idiopathic arthritis. Next to being a master regulator of inflammation, IL‐6 also is an important regulator of haemostasis. Although generally well tolerated,
Charlotte D. C. C. van der Heijden, Loes C. Oskam, Lenny van Bon, Chantal P. Rovers   +3 more
wiley   +1 more source

Prognostic benefit of immunosuppressive agents in primary Sjögren's syndrome patients with hypergammaglobulinemia. [PDF]

Front Immunol
Zhang L, Zou Y, Chen D, Zhang X, Jia Z, Zhang Q, Wang F, Feng X.   +7 more
europepmc   +1 more source

IgG4‐Related Disease Overlapping With Anti‐Acetylcholine Receptor Antibody–Positive Myasthenia Gravis

Clinical and Experimental Neuroimmunology, Volume 17, Issue 3, August 2026.
ABSTRACT Background IgG4‐related disease (IgG4‐RD) is a systemic, immune‐mediated, fibroinflammatory disorder with multiorgan involvement and variable clinical presentation, often creating diagnostic difficulty. Myasthenia gravis (MG) is an antibody‐mediated autoimmune disorder of the neuromuscular junction, most commonly associated with anti ...
Yumiko Yoshida, Ayami Okuzumi, Yuka Hosaka, Yuji Tomizawa, Taku Hatano   +4 more
wiley   +1 more source

Relationship between lacrimal gland changes and corneal parameters in patients with primary Sjögren's syndrome and non-Sjögren's syndrome-related dry eye. [PDF]

Front Med (Lausanne)
Zhou W, Liu C, Yang B, Li J, Yu H, Yao Z, He X, Wang S, Feng Y.   +8 more
europepmc   +1 more source

Interleukin‐40 in Systemic Sclerosis: A Treatment‐Sensitive Marker of Immune Modulation Rather Than Disease Activity

Clinical and Translational Science, Volume 19, Issue 8, August 2026.
ABSTRACT Interleukin‐40 (IL‐40) is a recently identified cytokine primarily produced by activated B cells and implicated in immune regulation across several autoimmune diseases. Although B cell–driven immune dysregulation plays a central role in systemic sclerosis (SSc), the circulating behavior and clinical relevance of IL‐40 in this disease remain ...
İbrahim Vasi, Emin Ümit Bağrıaçık, Rıza Can Kardaş, Nihan Örüklü, Melek Yaman, Derya Yıldırım, Burcugül Kaya, Rahime Duran, İbrahim Karaduman, İbrahim Yahya Çakır, Hamit Küçük, Berna Göker, Abdulsamet Erden, Mehmet Akif Öztürk   +13 more
wiley   +1 more source

Correction: Primary Sjögren's syndrome-associated immune thrombocytopenia: from pathogenesis to treatment. [PDF]

Front Immunol
Zheng Z, He T, Zhang G, Fu G, Liu C.
europepmc   +1 more source

A Phase 2 Trial of Frexalimab, a CD40L Antagonist, in Adolescents and Adults With Recent‐Onset Type 1 Diabetes (FABULINUS): Rationale and Study Design

Diabetes, Obesity and Metabolism, Volume 28, Issue 8, Page 6584-6594, August 2026.
ABSTRACT Introduction Type 1 diabetes (T1D) is a chronic autoimmune disease, characterised by progressive destruction of the insulin‐producing pancreatic β‐cells. Preserving remaining β‐cells at the time of diagnosis may improve long‐term outcomes. Frexalimab is a humanised monoclonal antibody specific for CD40L undergoing evaluation for treatment of ...
Andriy Cherkas, Baerbel Rotthaeuser, Niels Porksen, Pascale Labard, My‐Liên Nguyên‐Pascal, Mathieu Coudert, Baptiste Berthou, Marie Baccara‐Dinet, Gabor Boka, Mark Peakman, Felix Reschke, Michael J. Haller   +11 more
wiley   +1 more source

Metabolite profiling of saliva for the discrimination of Behcet's disease, Sjögren's syndrome, and recurrent aphthous stomatitis. [PDF]

PLoS One
Kim S, Zhang M, Ahn JK, Hwang J.
europepmc   +1 more source

Examining the Role of Artificial Intelligence in Assessment: A Comparative Study of ChatGPT and Educator‐Generated Multiple‐Choice Questions in a Dental Exam

European Journal of Dental Education, Volume 30, Issue 3, Page 881-895, August 2026.
ABSTRACT Aim To compare the item difficulty and discriminative index of multiple‐choice questions (MCQs) generated by ChatGPT with those created by dental educators, based on the performance of dental students in a real exam setting. Materials and Methods A total of 40 MCQs—20 generated by ChatGPT 4.0 and 20 by dental educators—were developed based on ...
Nezaket Ezgi Özer, Yusuf Balcı, Gaye Bölükbaşı, Betul İlhan, Pelin Güneri   +4 more
wiley   +1 more source

Elevated IL-8 and abnormal lymphocytes in pediatric primary Sjögren's syndrome: a single-center study. [PDF]

Eur J Med Res
Gao XF, Tang W, Huang X, Liua Y, Zhou J, Nie Z, Zhao M, Tang Y, Li F, Xu C, Chen H, Zeng P.   +11 more
europepmc   +1 more source