Results 161 to 170 of about 18,718 (235)

Methotrexate Toxicity in a Patient With Renal Failure Despite a Normal Methotrexate Concentration: A Case Report and Literature Review

open access: yesClinical Case Reports, Volume 14, Issue 6, June 2026.
ABSTRACT Methotrexate (MTX) is a folate antagonist widely used as a disease‐modifying antirheumatic drug (DMARD) in rheumatoid arthritis (RA), as well as in several malignancies and autoimmune disorders. Although low‐dose MTX (5–20 mg/week) is generally considered safe, it has a narrow therapeutic index, and toxicity can occur even at therapeutic doses,
Fatemeh Afra   +7 more
wiley   +1 more source

Syncope as the Initial Presentation of Takayasu Arteritis in a 57‐Year‐Old Female: A Case Report and Literature Review

open access: yesClinical Case Reports, Volume 14, Issue 6, June 2026.
ABSTRACT Takayasu arteritis (TA) is a rare chronic granulomatous large‐vessel vasculitis predominantly affecting the aorta and its major branches, leading to stenosis, occlusion, or aneurysm formation. It typically presents in young women, though atypical cases can occur in older adults.
Chao Liu   +6 more
wiley   +1 more source

Oral Lesions Developed in Post‐Hematopoietic Stem Cell Transplant Patients and the Role of Cryogun Cryotherapy

open access: yesClinical and Experimental Dental Research, Volume 12, Issue 3, June 2026.
ABSTRACT Objective To investigate the development of oral premalignant and malignant lesions as a major long‐term complication following hematopoietic stem cell transplantation. Methods This single‐center retrospective study identified 17 patients who developed 26 pathology‐confirmed oral premalignant and malignant lesions after hematopoietic stem cell
Pei Hsuan Lu   +3 more
wiley   +1 more source

Elevated IL-8 and abnormal lymphocytes in pediatric primary Sjögren's syndrome: a single-center study. [PDF]

open access: yesEur J Med Res
Gao XF   +11 more
europepmc   +1 more source

TGF‐β1‐driven epithelial‒mesenchymal transition mediates the fibrotic process in IgG4‐related disease

open access: yesClinical and Translational Discovery, Volume 6, Issue 3, June 2026.
In IgG4‐related disease, the epithelial‐to‐mesenchymal transition of fibroblasts was predominantly driven by transforming growth factor‐β1 secreted from CD19+ B cells. Reciprocally, fibroblasts facilitated CD19+ B‐cell survival and activation through CXCL14–CXCR4 and CXCL12–CXCR4 signalling axes, thereby promoting B‐cell responses and subsequent ...
In‐Woon Baek   +2 more
wiley   +1 more source

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