Results 181 to 190 of about 27,645 (290)

Identification of SDC1 as a Key Regulator and Therapeutic Target in Rheumatoid Arthritis via JAK2‐STAT3 Pathway

International Journal of Rheumatic Diseases, Volume 29, Issue 2, February 2026.
ABSTRACT Introduction Rheumatoid arthritis (RA) is a chronic autoimmune disorder with unclear molecular mechanisms, complicating early diagnosis and treatment. This study aimed to identify hub genes and pathways driving RA pathogenesis and assess their therapeutic potential.
Gan Cao, Zhihui Wu, Yatao Du, Dongxue Dai, Yang Sun, Xi Jia, Huixin Cai   +6 more
wiley   +1 more source

Educational Case: Connective tissue disorders: Sjögren's syndrome. [PDF]

Acad Pathol
Patterson AS, Robbins QC, Knollmann-Ritschel B.   +2 more
europepmc   +1 more source

Pharmacogenomics of Thiopurine Drugs: A Bench‐To‐Bedside Success Story in Thailand

Clinical and Translational Science, Volume 19, Issue 2, February 2026.
ABSTRACT Thiopurine drugs are the cornerstone treatment for many diseases such as acute lymphoblastic leukemia (ALL), organ rejection, inflammatory bowel disease (IBD), systemic lupus erythematosus (SLE), rheumatoid arthritis (RA) and other autoimmune diseases.
Mohitosh Biswas, Shobana John, Murshadul Alam Murad, Chonlaphat Sukasem   +3 more
wiley   +1 more source

Meningoencephalitis as a presentation of primary Sjögren's syndrome: a case report. [PDF]

J Med Case Rep
Karim AK, Gorial FI, Badi IA, Mahdi FJ, Awadh NI, Hassan AM, Juma'a MK.   +6 more
europepmc   +1 more source

First‐in‐Human Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of ASP1617, a Cathepsin‐S Inhibitor, in Healthy Adult Subjects

Clinical and Translational Science, Volume 19, Issue 2, February 2026.
ABSTRACT ASP1617 is a novel, highly selective inhibitor of cathepsin‐S, an important protease for antigen peptide loading onto major histocompatibility complex class II molecules. Preclinically, ASP1617 prevented progression of lupus‐like glomerulonephritis in an NZB/W F1 mouse model of systemic lupus erythematosus.
Tomoki Kojima, Wei Chen, Ronald Smulders, Stephen Stanhope, Donna Kowalski, Nakyo Heo, Selina Moy, Amanda Goldston, David Han, Tong Zhu   +9 more
wiley   +1 more source

An Unusual Gastrointestinal Presentation of Sjogren's Syndrome: A Case Report. [PDF]

Clin Case Rep
Sahwan O, Jamal F, Elshaer A, Batha L, Shahin T, Pham MM.   +5 more
europepmc   +1 more source

Cryoglobulinemia: An update on classification, pathophysiology, clinical presentation, and management

Journal of Internal Medicine, Volume 299, Issue 2, Page 196-215, February 2026.
Abstract Cryoglobulinemia (CG) is defined by the presence of serum immunoglobulins that precipitate below 37°C and redissolve upon rewarming. It is classified into three types based on immunoglobulin composition. Type I, a rare form, involves monoclonal IgM or IgG and is linked to lymphoproliferative disorders.
Anna Linda Zignego, Laura Gragnani, Marcella Visentini, Riccardo Bomben, Luca Arcaini, Clodoveo Ferri, Valter Gattei, Cesare Mazzaro   +7 more
wiley   +1 more source

Chronic autonomic neuropathy in a patient with primary Sjogren's syndrome

, 2000
Hirofumi Goto
openalex   +1 more source

Clinical and pathological differences between Mikulicz's disease and Sjogren's syndrome [PDF]

, 2004
Motohisa Yamamoto, Shigenori Harada, Mikiko Ohara, Chisako Suzuki, Y. Naishiro, Hiroyuki Yamamoto, Hiroki Takahashi, Koji Imai   +7 more
openalex   +1 more source

New‐onset autoimmune disease following SARS‐CoV‐2 infection and mRNA vaccination in Norway: A retrospective cohort study

Journal of Internal Medicine, Volume 299, Issue 2, Page 271-282, February 2026.
Abstract Background Studies suggest an increase in autoimmune diseases following SARS‐CoV‐2 infection and/or COVID‐19‐vaccination. We aimed to describe possible associations in Norway. Methods We used information from the emergency preparedness register for COVID‐19, BeredtC19, for all residents aged 18–64 (N = 3,450,080).
Håkon Bøås, Paz Lopez‐Doriga Ruiz, Jesper Dahl, Hanne L. Gulseth, German Tapia   +4 more
wiley   +1 more source