Results 91 to 100 of about 1,167,016 (249)

Sjogren’s syndrome: apoptosis by anti-SSA and anti-SSB antibodies

, 2011
The pathogenesis of the Sjogren’s Syndrome (SjS) has not yet been completely defined. However, the cell-mediated immunity plays an important role and the apoptosis of the ductal and acinar epithelial cells is responsible of the glandular tissue damage ...
M. D'Amore, S. D'Amore, P. Scagliusi, A. Scagliusi   +3 more
core   +1 more source

TRIM Expression and Its Association With Disease Activity in Systemic Lupus Erythematosus

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Systemic lupus erythematosus (SLE) is a chronic autoimmune disease with diverse manifestations, including rash, arthritis, and nephritis. Although autoantibodies are a key feature of SLE, their levels often poorly reflect disease severity, suggesting the involvement of additional contributing factors.
Ling‐Ying Lu, Ling‐Jung Yen, Hui‐Ling Hsia, Zi‐Xeng Weng, Chi‐Hsiang Chung, Paul Wei‐Che Hsu, Chih‐Wei Chiu, Wu‐Chien Chien, Tsung‐Hsien Chang   +8 more
wiley   +1 more source

Antigen-driven clonal proliferation of B cells within the target tissue of an autoimmune disease: the salivary glands of patients with Sjögren's syndrome [PDF]

, 1998
Structures resembling germinal centers are seen in the salivary glands of patients with Sjögren's syndrome, but it is not known whether the microenvironment of these cell clusters is sufficient for the induction of a germinal center response.
G Steinhauser, M Hummel, D I Stott, C Berek, Hiepe, F., Berek, C., F Hiepe, Hummel, M., Steinhauser, G., Stott, D.I.   +9 more
core   +1 more source

Collagen‐membrane‐covered matrix‐associated chondrocyte implantation improves safety over periosteum‐covered MACI for large knee cartilage defects: A real‐world data analysis in the registry study

Knee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Purpose This registry study aimed to evaluate the safety and effectiveness of collagen membrane‐covered matrix‐associated autologous chondrocyte implantation (cMACI) versus periosteum‐covered MACI (pMACI) for large knee cartilage defects (Outerbridge III–IV, ≥4 cm²) in the femorotibial and/or patellofemoral joints with a minimum 2‐year follow ...
Yuji Uchio, Ryosuke Kuroda, Yasuo Niki, Katsura Sugawara, Yasuyuki Ishibash   +4 more
wiley   +1 more source

Factors Associated With Bilateral Involvement in Non‐Infectious Labyrinthitis: A Case–Control Study

The Laryngoscope, EarlyView.
Non‐infectious labyrinthitis may progress from unilateral to bilateral inner‐ear involvement, resulting in greater functional impairment. In this retrospective case–control study of 50 patients, younger age, female sex, and the presence of systemic disease were associated with bilateral involvement. These exploratory findings may help identify patients
Douglas Henderson, Blanca Amador Borrero, Aurélien Cadix, Karine Champion, Damien Sene, Philippe Herman, Charlotte Hautefort, Alain Londero, Michael Eliezer, Cassandre Djian   +9 more
wiley   +1 more source

An abnormal T cell repertoire in hypergammaglobulinaemic primary Sjogren’s syndrome

, 1991
SUMMARY T cell antigen specificity is determined by the products of the genes which encode the variable regions of their receptors. Of the T cell receptor (TCR) variable region gene products examined, only Vβ6.7a TCR-positive lymphocytes ...
P A DYER, C DENNETT, W E R OLLLER, R M BERNSTEIN, E M HAY, R S H PUMPHREY, R A KAY, A W BOYLSTON, L M GREEN, P J L HOLT   +9 more
core   +1 more source

Etiopathogenesis of Sjogren’s Syndrome

, 2016
Sjogren’s syndrome (SS) is a chronic autoimmune disease, primarily affecting middle-aged women. The major SS characteristic is the accumulation of periepithelial lymphocytic cell infiltrates in the exocrine glands, mainly labial and lachrymal glands ...
Mavragani, C.P., Nezos, A.
core   +1 more source

Chronic polydipsia and polyuria as rare renal manifestations of Sjögren's syndrome

EULAR Rheumatology Open
: Sjögren's syndrome is a chronic autoimmune disorder that primarily affects the exocrine glands, with renal involvement observed in a minority of cases. We present the case of a 31-year-old woman with an 8-year history of chronic polydipsia and polyuria
Vanessa Bartsch, Christiane Stark, Kathrin Standfest, Martin Blos, Stefan Knop, Axel J Hueber   +5 more
doaj   +1 more source

Mesenteric Panniculitis in Sjögren’s Syndrome: A New Systemic Manifestation to Consider?

European Journal of Case Reports in Internal Medicine, 2018
The association between mesenteric panniculitis and Sjögren's syndrome, although rare, is starting to be recognized. Usually, mesenteric panniculitis is symptomatic, presenting with either general or gastrointestinal symptoms.
Patrícia Afonso Mendes, Diana Marques Ferreira, Helena Temido, Rui Pina, Armando Carvalho   +4 more
doaj   +1 more source

Electrophysiologic Demyelinating Features Are Common in Vasculitic Neuropathy: A Cohort of Biopsy‐Confirmed Cases

Muscle &Nerve, EarlyView.
ABSTRACT Introduction/Aims Electrophysiologic features suggestive of demyelination have been reported in vasculitic neuropathy, complicating the diagnostic process, but their frequency is unknown. We aimed to determine the prevalence of demyelinating features, including fulfillment of European Academy of Neurology/Peripheral Nerve Society (EAN/PNS ...
Alexandra Maury, Guillemette Beaudonnet, Thierry Maisonobe, Christian Denier, Andoni Echaniz‐Laguna, Clovis Adam, Céline Labeyrie, Edouard Berling   +7 more
wiley   +1 more source