Results 111 to 120 of about 25,653 (241)
Multiple Roles for B-Lymphocytes in Sjogren’s Syndrome
, 2016 Sjogren’s syndrome (SS) is a complex heterogeneous autoimmune disease resulting in loss of salivary gland and lacrimal gland function that may include multiple systemic manifestations including lymphoma.
Lakshmanan Suresh +2 more
core +1 more source
Dry eye disease symptoms and associated risk factors in a Norwegian clinical cohort
Acta Ophthalmologica, EarlyView.Abstract Background The relationship between dry eye disease (DED) symptoms and different demographic, clinical and lifestyle factors remains poorly understood. Norway's cold climate and dry indoor air may accelerate tear evaporation, contributing to a very high meibomian gland dysfunction prevalence, as found in multiple studies.
Mazyar Yazdani +6 more
wiley +1 more source
A rare presentation of Sjogren\'s syndrome with ascites and liver fibrosis in a young woman: a Case report [PDF]
مجله دانشگاه علوم پزشکی بیرجندPrimary Sjogren's syndrome is a systemic autoimmune disease that encompasses a wide range of manifestations, including exocrine gland involvement and extra-glandular symptoms.
Mohammad Reza Farzaneh Far +4 more
doaj
British Journal of Haematology, EarlyView.Summary Childhood autoimmune neutropenia (AIN) encompasses heterogeneous entities; phenotype‐specific immunological profiles and their relationship to infection outcomes remain incompletely defined. To characterise clinical, immunological and long‐term outcomes across distinct phenotypes of childhood AIN.
Ioanna Saougou +5 more
wiley +1 more source
Scientific ReportsIdentification of an early biomarker and effective testing device to differentiate dry eye disease secondary to autoimmune disease (Sjögren’s syndrome dry eye disease) from non-Sjögren’s dry eye disease are prerequisites for appropriate treatment.
Chia-Ying Tsai +7 more
doaj +1 more source
Exposure to perfluoroalkyl acids (PFAAs) has been found to elicit a range of detrimental effects on human health. However, limited research has investigated the impact of PFAAs on immunity and immune disorders such as Sjogren’s syndrome, with existing ...
Jing Xue +6 more
core +1 more source
Diagnosis and treatment of primary Sjogren’s syndrome: an update
, 2017 Primary Sjogren’s syndrome (SS) is a systemic autoimmune disease that primarily affects the exocrine glands, resulting in dryness of the mucosal membranes, particularly of the eyes and mouth.
Chiu Sum Chu, Chi Chiu Mok
core +1 more source
Diagnosis and management of neutropenia in adults: Expert guidance
British Journal of Haematology, EarlyView.Severe neutropenia can result from decreased production of neutrophil precursors in the bone marrow, as in the case of severe congenital neutropenia, or from increased utilization of neutrophils or their accelerated destruction as for drug‐induced neutropenia or autoimmune neutropenia. Severe chronic neutropenia increases susceptibility to bacterial or
Karl Welte +5 more
wiley +1 more source
Haemostatic changes and bleeding with anti‐IL‐6 directed therapy in autoimmune diseases
British Journal of Pharmacology, EarlyView.Abstract Anti‐IL‐6 directed therapy, especially tocilizumab (TCZ), is widely used for the treatment of autoimmune diseases such as rheumatoid arthritis, giant cell arteritis and systemic juvenile idiopathic arthritis. Next to being a master regulator of inflammation, IL‐6 also is an important regulator of haemostasis. Although generally well tolerated,
Charlotte D. C. C. van der Heijden +3 more
wiley +1 more source
Cell Proliferation, EarlyView.This study elucidates a novel Kupffer cell‐neutrophil‐hepatocyte axis that drives metabolic‐immune crosstalk during acute liver failure. Specifically, lactate‐primed NETs release links metabolic reprogramming to NETosis‐induced regenerative failure in hepatocytes via the TLR9/KLF15/AJUBA axis.
Jin Guo +5 more
wiley +1 more source