Results 121 to 130 of about 27,132 (250)

Mesenchymal stromal cell therapy for rheumatoid arthritis: Long‐term efficacy, safety, and mechanistic insights

open access: yesRheumatology &Autoimmunity, EarlyView.
Graphical abstract summarizing the multifactorial pathogenesis of rheumatoid arthritis (RA) and the therapeutic potential of mesenchymal stromal cell (MSC) therapy. MSCs provide promising benefits through their immunomodulatory properties, low immunogenicity, ability to promote tissue repair, and multi‐lineage differentiation, presenting a potential ...
Yingjia Chen   +6 more
wiley   +1 more source

Improving Medical‐Dental Integration Through Inter‐Provincial, Inter‐Professional Collaboration

open access: yes
Journal of Dental Education, EarlyView.
Ishita Patel   +3 more
wiley   +1 more source

Association of autoimmune diseases with biologic agents targeting type 2 immunity: An observational study using a claims database

open access: yesRheumatology &Autoimmunity, EarlyView.
This observational study assessed the association between anti‐type 2 biologic agents and the occurrence of autoimmune diseases using a large real‐world claims database. Anti‐IL‐5 and anti‐IgE therapies were associated with an increased occurrence of autoimmune diseases, including rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE ...
Shoichiro Inokuchi
wiley   +1 more source

Cardiac disease in systemic sclerosis: Integrating pathobiology with clinical management

open access: yesRheumatology &Autoimmunity, EarlyView.
Abstract Systemic sclerosis (SSc) is a complex autoimmune disorder in which cardiovascular involvement remains a major determinant of morbidity and mortality. Cardiac injury in SSc results from the interplay of microvascular dysfunction, immune‐mediated inflammation, and progressive interstitial and replacement fibrosis, leading to myocardial disease ...
Henry Sutanto, Betty Rachma, Yuliasih
wiley   +1 more source

Histopathological Characterization and Differential Expression of miRNAs in Male Pediatric Patients With Lichen Sclerosus

open access: yesAndrology, EarlyView.
ABSTRACT Background Lichen sclerosus is a chronic, inflammatory, scarring disease of the skin that manifests mostly in the genital region. Objective We studied the histomorphological characteristics, grade, and pattern of inflammation in male pediatric patients with lichen sclerosus.
Valerie Flammang   +10 more
wiley   +1 more source

Chapter 6 - Cerebrospinal fluid in the dementias [PDF]

open access: yes, 2017
Alzheimer disease, vascular dementia, dementia with Lewy bodies, and frontotemporal dementia are the most common central nervous system disorders that cause progressive neurocognitive dysfunction and ultimately dementia.
Rohrer, JD, Schott, JM, Zetterberg, H
core  

Outcome parameters in studies investigating dry eye disease: A systematic literature review

open access: yesActa Ophthalmologica, EarlyView.
Abstract The development of effective therapeutics for dry eye disease (DED) is challenging due to its complex pathophysiology, heterogeneous patient presentation and the significant failure rate of previous clinical development programs. This underlines the importance of the selection of appropriate endpoints for clinical trials.
Viktoria Pai   +8 more
wiley   +1 more source

IRF4 Enhances Radiosensitivity of Cervical Cancer by Inhibiting the PI3K/Akt/mTOR Pathway to Regulate Autophagy

open access: yesCancer Science, EarlyView.
IRF4 is a prognostic biomarker in cervical cancer. IRF4 enhances radiosensitivity and inhibits tumor growth via PI3K/AKT/mTOR‐mediated autophagy. IRF4 boosts radiation response in vitro and in vivo. ABSTRACT Interferon regulatory factor 4 (IRF4), a critical member of the IRF transcription factor family, harbors an elusive biological role in cervical ...
Meihui Gao   +9 more
wiley   +1 more source

Association between Sjögren syndrome, sociodemographic factors, comorbid conditions, and optic neuritis: a Taiwanese population-based study

open access: yesFrontiers in Neurology
PurposeOur study aimed to explore the correlation between Sjögren syndrome, sociodemographic factors, comorbid conditions, and optic neuritis.MethodsThis retrospective, nationwide, population-based, matched case–control investigation involved 33,190 ...
Ren-Long Jan   +10 more
doaj   +1 more source

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