Characterization of the human omega-oxidation pathway for omega-hydroxy-very-long-chain fatty acids [PDF]
, 2008 Very-long-chain fatty acids (VLCFAs) have long been known to be degraded exclusively in peroxisomes via beta-oxidation. A defect in peroxisomal beta-oxidation results in elevated levels of VLCFAs and is associated with the most frequent inherited ...
Dacremont, Georges +4 more
core +2 more sources
Neonatal lupus with atypical cardiac and cutaneous manifestation [PDF]
, 2013 Neonatal lupus erythematosus is a rare, passively acquired autoimmune disease, caused by maternal autoantibodies. The most common manifestations are skin rash and congenital heart block. Cutaneous manifestations may be present at birth, but often develop
Mimoso, G +3 more
core +1 more source
Conjunctival Inflammation in Thrombospondin-1 Deficient Mouse Model of Sjögren’s Syndrome [PDF]
, 2014 Lacrimal gland inflammation during autoimmune Sjögren’s syndrome (SS) leads to ocular surface inflammation – Keratoconjunctivitis sicca (KCS). This condition afflicts both the cornea and conjunctiva that form the ocular surface.
Contreras-Ruiz, Laura +4 more
core +1 more source
Validation of Smart Nanoparticles as Controlled Drug Delivery Systems: Loading and pH-Dependent Release of Pilocarpine [PDF]
, 2018 Micelles are good devices for use as controlled drug delivery systems because they exhibit the ability to protect the encapsulated substance from the routes of degradation until they reach the site of action.
Galbis Fuster, Elsa +6 more
core +6 more sources
Un caso inusual de linfoma de células B de la glándula parótida a complicar el Síndrome de Sjögren
Galicia Clínica, 2020 Sjögren Syndrome is a multisystemic autoimmune disease that is heterogeneous in its presentation, course and outcome. There is no single clinical, laboratorial or radiological feature that serves as gold standard for the diagnosis and/or classification ...
Diana Gonçalves +3 more
doaj +1 more source
Ataxia in children: early recognition and clinical evaluation [PDF]
, 2017 Background: Ataxia is a sign of different disorders involving any level of the nervous system and consisting of impaired coordination of movement and balance.
Falsaperla, Raffaele +6 more
core +1 more source
Ageing, physical function, and the diurnal rhythms of cortisol and dehydroepiandrosterone [PDF]
, 2012 The present study examined the relationship between ageing, physical function and the diurnal rhythms of cortisol and dehydroepiandrosterone (DHEA). Participants were 36 community dwelling older adults aged between 65-86 years old.
Aardal +57 more
core +1 more source
Association of Sicca Syndrome with Proviral Load and Proinflammatory Cytokines in HTLV-1 Infection
Journal of Immunology Research, 2016 The Sjögren syndrome has been diagnosed in patients with HTLV-1 associated myelopathy and dry mouth and dry eyes are documented in HTLV-1 carriers. However the diagnosis of Sjögren syndrome in these subjects has been contested.
Clara Mônica Lima +7 more
doaj +1 more source
Corneal confocal microscopy alterations in Sjögren syndrome dry eye [PDF]
, 2016 PurposeTo evaluate light backscattering (LB) in corneal layers in patients with primary Sjögren's syndrome dry eye (SSDE) utilizing in vivo corneal confocal microscopy (IVCM) and to determine the eventual association with the lacrimal functional test ...
Afonso +30 more
core +1 more source
Arthritis Care &Research, Accepted Article.Objectives Sjögren's disease is an autoimmune disorder that can impact multiple organ systems, including the peripheral nervous system (PNS). PNS manifestations, which can exist concurrently, include mononeuropathies, polyneuropathies, and autonomic nervous system neuropathies. To help patients and providers in the decision‐making process, we developed
Anahita Deboo +19 more
wiley +1 more source