Results 191 to 200 of about 100,050 (291)

Senomorphic Small Extracellular Vesicles Delivered by a Tissue‐Adhesive α‐Lipoic‐Acid Hydrogel Enable Immuno‐Rejuvenation for Bone‐Tendon Interface Regeneration

Advanced Science, EarlyView.
This work identifies M1 macrophage‐mediated inflammation as a key driver of BMSC senescence and bone microstructural deterioration at the enthesis. A tissue‐adhesive hydrogel delivering senomorphic small extracellular vesicles suppresses this inflammatory‐senescent cascade and enhances BMSC resilience by inhibiting the cGAS‐STING‐NF‐κB pathway.
Lingzhi Kong, Wei Song, Wencai Liu, Hui Xu, Yuhao Yu, Xinyue Yang, Haiyan Li, Yanlun Zhu, Yaohua He   +8 more
wiley   +1 more source

PIEZO1 Channels Modulate the Small Extracellular Vesicle Release in C2C12 Cells. [PDF]

J Cell Physiol
Annalisa B, Ru ZW, Laura SS, Alessia N, Anna F, Marianna L, Marina S, Griffoni A, William RK, Giulio T, Paola L, Agenor L.   +11 more
europepmc   +1 more source

Multiparametric Bioresorbable Sensor for Doxorubicin Detection via Molecularly Imprinted Synthetic Receptors

Advanced Science, EarlyView.
A biodegradable molecularly imprinted polymer porous silica sensor enables dual optical readout of doxorubicin via fluorescence and effective optical thickness shifts. The combined transduction mechanisms provide enhanced reliability and quantitative accuracy over clinically relevant concentrations, representing a step toward transient implantable ...
Martina Corsi, Tiziano Di Giulio, Eleonora Vandini, Muhammad Ibrar Asif, Eleonora Daini, Antonietta Vilella, Giuseppina Leo, Alessandra Ottani, Cosimino Malitesta, Daniela Giuliani, Elisabetta Mazzotta, Giuseppe Barillaro   +11 more
wiley   +1 more source

Periosteal mitochondria DNA structures drive aging-associated poor skeletal repair. [PDF]

Bone Res
Wu Y, Han C, Yang X, Wang Y, Tian W, Yuan Q, Wang H, Wang H, Yin B, Ye L, Li F, Yu F.   +11 more
europepmc   +1 more source

Interfacially Reinforced Crosslinked Binder with Structural Integrity for Stable Micro‐Sized Silicon Anodes in All‐solid‐state Batteries

Advanced Science, EarlyView.
ABSTRACT All‐solid‐state batteries (ASSBs) have attracted considerable attention as next‐generation energy storage systems owing to their high energy density and safety. However, their performance is critically limited by insufficient solid–solid interfacial contact and severe chemomechanical degradation, particularly for micro‐sized silicon (µSi ...
Chanho Lee, Yuri Nam, Incheol Jeong, Seo Eun Lee, Taewook Kim, Jinhyung Kim, Wooseup Jo, Moonsu Yoon, Jongkyeong Lim, Seho Sun, Junghyun Choi, Chan Ho Park, Dongsoo Lee   +12 more
wiley   +1 more source

MicroCT Enables Simultaneous Longitudinal Tracking of Murine Pancreatic Cancer Progression and Cachexia. [PDF]

Cancer Res Commun
Pelz KR, Jimenez P, Daniel CJ, Newton SD, Cunningham M, Sears RC, Worth PJ, Brody JR, Zimmers TA.   +8 more
europepmc   +1 more source

Harnessing Phase Separation for the Development of High‐Performance Hydrogels

Advanced Science, EarlyView.
ABSTRACT Hydrogels are indispensable for the development of next‐generation bioelectronics, soft robotics, and biomedical devices, where their mechanical properties determine performance and reliability. Among strategies to enhance hydrogel mechanics, phase separation enables controlled heterogeneity resulting in gel networks that are reinforced by ...
Yue Shao, Yiming Ma, Baihao Shao, Molly M. Stevens   +3 more
wiley   +1 more source

Transcatheter Intra-Arterial Delivery of a Platelet-Derived Extracellular Vesicle-Enriched Preparation for Attenuating Skeletal Muscle Ischaemia-Reperfusion Injury in a Rodent Forelimb Model. [PDF]

J Extracell Vesicles
Selim OA, Sarcon A, Behfar A, Zhao C, Moran SL.   +4 more
europepmc   +1 more source

In Situ Formation of an In–Zn Interface Layer Enables Aqueous Zinc‐Ions Batteries with High Capacity Retention

Advanced Science, EarlyView.
This work demonstrates an indium zinc oxide (IZO)‐modified separator applied to aqueous zinc ion batteries (AZIBs), which in situ generates an In–Zn interface layer to stabilize the separator/anode region during the cycling process. The In–Zn interface layer provides richer nucleation sites for Zn2+ and suppresses side reactions.
Youwei Jiang, Jinghao Li, Jie Huang, Tan Qiu, Xiuwen Song, Fujun Deng, Yongxue Wang, Yue Ming, Ziping Wu, Qinyou An, Yaoguang Rong   +10 more
wiley   +1 more source