Results 31 to 40 of about 32,983 (252)

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Musculoskeletal application and validation of speckle-tracking ultrasonography

BMC Musculoskeletal Disorders, 2019
Background Diseased, injured, or dysfunctional skeletal muscles may demonstrate abnormal function and contractility. Currently, only few in vivo imaging techniques are able to characterize the contractile properties of muscle tissue.
Lars Henrik Frich, Kate Lykke Lambertsen, John Hjarbaek, Jordi Sanchez Dahl, Anders Holsgaard-Larsen   +4 more
doaj   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

An Ensemble of Long Short‐Term Memory Models to Automatically Detect End‐Range Movement Patterns in Men's Professional Hard Court Grand Slam Tennis

European Journal of Sport Science
Evaluating end‐range movements during tennis match‐play can quantify high intensity load exposure and facilitate specific analysis of players' high‐end physical capabilities.
Cameron Armstrong, Peter Peeling, Alistair Murphy, Simon Denman, Machar Reid   +4 more
doaj   +1 more source

Plasma EV Proteomics Identifies ECM Remodeling and Inflammatory Proteins LUM and C7 as Candidate Biomarkers in FSHD

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit, Chiranth K. Nagaraj, Jackson S. Newell, Kim Truc Nguyen, Xilal Y. Rima, Jacob Doon‐Ralls, Eduardo Reátegui, Jeffrey M. Statland, Rabi Tawil, Kevin M. Flanigan, Scott Q. Harper, Nizar Y. Saad   +11 more
wiley   +1 more source

Performance Evaluation of Monocular Markerless Pose Estimation Systems for Industrial Exoskeletons

Sensors
Industrial exoskeletons (a.k.a. wearable robots) have been developed to reduce musculoskeletal fatigue and work injuries. Human joint kinematics and human–robot alignment are important measurements in understanding the effects of industrial exoskeletons.
Soocheol Yoon, Ya-Shian Li-Baboud, Ann Virts, Roger Bostelman, Mili Shah, Nishat Ahmed   +5 more
doaj   +1 more source

Skeletal maturity and body size of teenage Belgian track and field athletes

Annals of Human Biology, 1986
Attained skeletal maturity (TW2 RUS method), skeletal maturity relative to chronological age, and body size of national-level Belgian track and field athletes 15 to 18 years of age were considered. Among the 47 male athletes, 29 (62%) were skeletally mature, while 15 (52%) of the 29 female athletes were skeletally mature.
R M, Malina, G, Beunen, R, Wellens, A, Claessens   +3 more
openaire   +2 more sources

White Matter and Perivascular Imaging Changes in Alzheimer's Disease and Cerebral Amyloid Angiopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Peak‐width of skeletonized mean diffusivity (PSMD) and diffusion tensor imaging–analysis along the perivascular space (DTI‐ALPS), reflecting white matter integrity and glymphatic function, are altered in Alzheimer's disease (AD).
Debina Laishram, Guangwei Du, Sangam Kanekar, Nandakumar Nagaraja   +3 more
wiley   +1 more source

Enhanced Human Skeleton Tracking for Improved Joint Position and Depth Accuracy in Rehabilitation Exercises

Applied Sciences
The objective of this work is to develop a method for tracking human skeletal movements by integrating data from two synchronized video streams. To achieve this, two datasets were created, each consisting of four different rehabilitation exercise videos ...
Vytautas Abromavičius, Ervinas Gisleris, Kristina Daunoravičienė, Jurgita Žižienė, Artūras Serackis, Rytis Maskeliūnas   +5 more
doaj   +1 more source

Modeling Dislocation Cutting of γ′ Precipitates in Ni‐Base Superalloys: Linking Atomistic and Dislocation Dynamics Simulations

Advanced Engineering Materials, EarlyView.
Dislocation cutting of γ′ precipitates in Ni‐based superalloys is investigated by linking atomistic simulations with discrete dislocation dynamics. The critical cutting stress is shown to be governed by the antiphase boundary energy, while line tension effects promote edge‐preferred cutting.
Frédéric Houllé, Siwen Gao, Marc Fivel, Anxin Ma, Daria Smirnova, Sriram Anand, Arun Prakash, Julien Guénolé, Alexander Hartmaier, Erik Bitzek   +9 more
wiley   +1 more source