Results 41 to 50 of about 11,483 (292)

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Text-Guided Sketch-to-Photo Image Synthesis

open access: yesIEEE Access, 2022
We propose a text-guided sketch-to-image synthesis model that semantically mixes style and content features from the latent space of an inverted Generative Adversarial Network (GAN).
Uche Osahor, Nasser M. Nasrabadi
doaj   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

3D Sketch Maps: Concept, Potential Benefits, and Challenges (Short Paper)

open access: yes, 2022
Studying the 3D aspect of spatial information has become increasingly important due to changes in the way we interact with the surrounding environments as well as technological innovations.
Kim, Kevin Gonyop   +7 more
core   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Can You Sketch in 3D? Exploring Perceived Feasibility and Use Cases of 3D Sketch Mapping [PDF]

open access: yes
Sketch mapping is a research technique that has been widely used to study what people think about the spatial layout of an environment. One of the limitations of the current practice of sketch mapping is that the interface (a pen on paper or digital ...
Kim, Kevin Gonyop   +6 more
core   +1 more source

L’espace vécu sur Tshitassinu : cartographie participative et représentations du territoire des jeunes Pekuakamiulnuatsh (Québec)

open access: yesRevue d'Études Autochtones
Au Canada, les Premières Nations accordent une importance croissante aux points de vue des jeunes dans leurs projets d’autodétermination politique et territoriale.
Irène Hirt   +3 more
doaj   +1 more source

Invariant spatial information in sketch maps — a study of survey sketch maps of urban areas

open access: yesJournal of Spatial Information Science, 2015
It is commonly recognized that free-hand sketch maps are influenced by cognitive impacts and therefore sketch maps are incomplete, distorted, and schematized. This makes it difficult to achieve a one-to-one alignment between a sketch map and its corresponding geo-referenced metric map.
Wang, Jia   +2 more
openaire   +3 more sources

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

Virtual/Real Transfer in a Large-Scale Environment: Impact of Active Navigation as a Function of the Viewpoint Displacement Effect and Recall Tasks

open access: yesAdvances in Human-Computer Interaction, 2013
The purpose of this study was to examine the effect of navigation mode (passive versus active) on the virtual/real transfer of spatial learning, according to viewpoint displacement (ground: 1 m 75 versus aerial: 4 m) and as a function of the recall tasks
Grégory Wallet   +3 more
doaj   +1 more source

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