Results 51 to 60 of about 11,483 (292)

An algorithmic approach to detect generalization in sketch maps from sketch map alignment

open access: yesPLOS ONE
Sketch maps are valuable tools used across various disciplines including spatial cognition, environmental psychology, and spatial reasoning. A common approach to evaluate sketch maps in research is to align and compare them with metric maps. However, sketch maps are highly abstract and contain generalized information causing difficulty in their ...
Charu Manivannan   +2 more
openaire   +3 more sources

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

open access: yesFEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

Pen and paper techniques for physical customisation of tabletop interfaces [PDF]

open access: yes, 2008
An advantage of physical interfaces over graphical widgets is that they bring controls closer to hand. VoodooSketch is a system that supports dynamic customisation of tabletop interfaces with physical controls that users can arrange on palettes.
Gutwin, Carl   +14 more
core   +1 more source

Analysis of brain activation patterns using a 3-D scale-space primal sketch

open access: yes, 1999
A fundamental problem in brain imaging concerns how to define functional areas consisting of neurons that are activated together as populations. We propose that this issue can be ideally addressed by a computer vision tool referred to as the scale-space ...
Roland, PE, Lindeberg, T, Lidberg, P
core   +2 more sources

Present Researching Approaches and Future Prospects for Treatment of Cardiac Diseases - Integrative Medicine

open access: yesWorld Journal of Traditional Chinese Medicine, 2015
The pathogenesis of cardiac diseases is very complex and involved in many gene transcription and protein expression. How to effectively treat the diseases has become the hotspot of modern medicine.
Yan Feng   +4 more
doaj   +1 more source

Electron transfer between complexes III and IV in S. cerevisiae mitochondrial membranes

open access: yesFEBS Letters, EarlyView.
Mitochondrial oxidative phosphorylation in S. cerevisiae mitoplasts is limited by complex IV catalytic capacity, rather than two‐dimensional cytochrome c diffusion. At physiological cytochrome c : supercomplex ratios at salinity equivalent to that of 20 mm monovalent salt, activity is maximized, indicating that this low ionic strength accurately mimics
Ana Paula Lobez   +2 more
wiley   +1 more source

Generating Map Sketches for Strategy Games [PDF]

open access: yes, 2013
How can a human and an algorithm productively collaborate on generating game content? In this paper, we try to answer this question in the context of generating balanced and interesting low-resolution sketches for game levels. We introduce six important criteria for successful strategy game maps, and present map sketches optimized for one or more of ...
Antonios Liapis   +2 more
openaire   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Enhancing Participatory Development in Morocco: Analyzing the Sketch Mapping Behavior of Men and Women and Integrating Paper and Digital Participatory Mapping Environments

open access: yes, 2022
Twelve participatory paper maps by separate groups of men and women were facilitated by the High Atlas Foundation in six communities in Morocco between 2010-2020 as part of their process of participatory development. In this thesis research, these sketch
Stern, Cora
core   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

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