Results 51 to 60 of about 208,882 (239)

Virtual/Real Transfer in a Large-Scale Environment: Impact of Active Navigation as a Function of the Viewpoint Displacement Effect and Recall Tasks

Advances in Human-Computer Interaction, 2013
The purpose of this study was to examine the effect of navigation mode (passive versus active) on the virtual/real transfer of spatial learning, according to viewpoint displacement (ground: 1 m 75 versus aerial: 4 m) and as a function of the recall tasks
Grégory Wallet, Hélène Sauzéon, Florian Larrue, Bernard N'Kaoua   +3 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

AAA+ protein unfoldases—the Moirai of the proteome

FEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

Present Researching Approaches and Future Prospects for Treatment of Cardiac Diseases - Integrative Medicine

World Journal of Traditional Chinese Medicine, 2015
The pathogenesis of cardiac diseases is very complex and involved in many gene transcription and protein expression. How to effectively treat the diseases has become the hotspot of modern medicine.
Yan Feng, Hao Xu, Yi-Xin Wang, Li-Ping Ma, Da-Zhuo Shi   +4 more
doaj   +1 more source

Learning from Synthetic Data Using a Stacked Multichannel Autoencoder

, 2015
Learning from synthetic data has many important and practical applications. An example of application is photo-sketch recognition. Using synthetic data is challenging due to the differences in feature distributions between synthetic and real data, a ...
Agam, Gady, Fu, Yanwei, Jiang, Shanshan, Sigal, Leonid, Zhang, Xi   +4 more
core   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Sketching-out virtual humans: A smart interface for human modelling and animation [PDF]

, 2007
In this paper, we present a fast and intuitive interface for sketching out 3D virtual humans and animation. The user draws stick figure key frames first and chooses one for “fleshing-out” with freehand body contours.
Mao, C, Qin, S F, Wright, D K
core   +1 more source

An algorithmic approach to detect generalization in sketch maps from sketch map alignment

PLOS ONE
Sketch maps are valuable tools used across various disciplines including spatial cognition, environmental psychology, and spatial reasoning. A common approach to evaluate sketch maps in research is to align and compare them with metric maps. However, sketch maps are highly abstract and contain generalized information causing difficulty in their ...
Charu Manivannan, Jakub Krukar, Angela Schwering   +2 more
openaire   +3 more sources

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source