Results 41 to 50 of about 20,831 (286)

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Sketch maps of the Leucite Hills, Wyoming

open access: yes, 1978
Sketch maps of the Leucite Hills ...
Palmer Ogden (10075153)
core   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Using sketch-maps for robot navigation: Interpretation and matching

open access: yes, 2016
We present a study on sketch-map interpretationand sketch to robot map matching, where maps have nonuniform scale, different shapes or can be incomplete.
Lilienthal, Achim J.,   +5 more
core   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

Contour detection network for zero-shot sketch-based image retrieval

open access: yesComplex & Intelligent Systems, 2023
Zero-shot sketch-based image retrieval (ZS-SBIR) is a challenging task that involves searching natural images related to a given hand-drawn sketch under the zero-shot scene. The previous approach projected image and sketch features into a low-dimensional
Qing Zhang   +4 more
doaj   +1 more source

Transmogrification: casual manipulation of visualizations

open access: yes, 2013
A transmogrifier is a novel interface that enables quick, on-the-fly graphic transformations. A region of a graphic can be specified by a shape and transformed into a destination shape with real-time, visual feedback.
John Brosz   +10 more
core   +1 more source

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

open access: yesFEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

Professor Muhammad Ilyas Barni (Late)

open access: yesبازیافت, 2019
Professor Muhammad Ilyas Barni was a man of diverse disciplines and a believer and practitioner of Islam. He wrote vigorously about theology, Prophet Muhammad (SAWW), Mysticism as well as  Economicsand Urdu Literature.
Abdul Haleem Chishti
doaj   +3 more sources

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