Results 51 to 60 of about 20,831 (286)

Spatial learning using Google Streetview in an online wayfinding task

Research in Learning Technology
The use of navigation applications changed the way people find their way in an unfamiliar environment. A combination of maps, images and textual route instructions shown (or with audio) on one screen guides the user to the destination but may sometimes ...
Vanessa Joy A. Anacta
doaj   +1 more source

Electron transfer between complexes III and IV in S. cerevisiae mitochondrial membranes

FEBS Letters, EarlyView.
Mitochondrial oxidative phosphorylation in S. cerevisiae mitoplasts is limited by complex IV catalytic capacity, rather than two‐dimensional cytochrome c diffusion. At physiological cytochrome c : supercomplex ratios at salinity equivalent to that of 20 mm monovalent salt, activity is maximized, indicating that this low ionic strength accurately mimics
Ana Paula Lobez, Mikael Oliveberg, Peter Brzezinski   +2 more
wiley   +1 more source

Generating Map Sketches for Strategy Games [PDF]

, 2013
How can a human and an algorithm productively collaborate on generating game content? In this paper, we try to answer this question in the context of generating balanced and interesting low-resolution sketches for game levels. We introduce six important criteria for successful strategy game maps, and present map sketches optimized for one or more of ...
Antonios Liapis, Georgios N. Yannakakis, Julian Togelius   +2 more
openaire   +1 more source

Very rough sketch maps

, 1938
4 maps on 4 sheets : color (hand-colored) ; each 45 x 35 cm.map 1: Birds: summary of: Uvea Is. (Loyalty Group. W. Pacific): contains information on the area of the tall original forest, area of shorter original forest (including garden area), area under ...
American Museum of Natural History. Department of Ornithology. Whitney South Sea Expeditions Collection., American Museum of Natural History., American Museum of Natural History, Macmillan, L., Macmillan, Lindsay., Whitney South Sea Expedition of the American Museum of Natural History (1920-1941), American Museum of Natural History. Department of Ornithology. Whitney South Sea Expeditions Collection.   +6 more
openaire   +2 more sources

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Categorical & coordinate spatial information: Can they be disentangled in sketch maps? [PDF]

, 2020
Humans tend to encode the environment by means of two types of spatial relations: coordinate (metric) and categorical (nonmetric). The present research contributes to methods for disentangling the contribution of categorical and coordinates spatial ...
Lopez, Antonella, Experimental Psychology (onderzoeksprogramma PF), Bosco, Andrea, Helmholtz Institute, Postma, Albert, Leerstoel Postma, Afd Psychologische functieleer   +6 more
core   +2 more sources

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Totally chiral maps and hypermaps of small genus

, 2009
An orientably regular hypermap is totally chiral if it and its mirror image have no non-trivial common quotients. We classify the totally chiral hypermaps of genus up to 1001, and prove that the least genus of any totally chiral hypermap is 211, attained
Jones, Gareth A., Breda d'Azevedo, Antonio, Jones, Gareth   +2 more
core   +1 more source