Results 71 to 80 of about 20,831 (286)

SketchMapia: A comprehensive way to analyse sketch maps [PDF]

open access: yes
Sketch mapping is a method used to investigate an individual's cognitive map of the surrounding environment. Sketch maps provide qualitative insights into individuals' mental representations of space.
Schwering, Angela   +2 more
core  

Decreased cold‐sensing function of the transient receptor potential channel TRPM8 from tailed amphibians

open access: yesFEBS Open Bio, EarlyView.
Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao   +3 more
wiley   +1 more source

Combined 5‐aminolevulinic acid and ferric ammonium citrate treatment promotes hair follicle growth by activating dermal papilla cells

open access: yesFEBS Open Bio, EarlyView.
5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

The Use of Sketch Maps to Measure Cognitive Maps of Virtual Environments

open access: yes, 1995
Cognitive maps are mental models of the relative locations and attributes of phenomena in spatial environments. Understanding how people form cognitive maps of virtual environments is vital to effective virtual world design.
Suzanne Weghorst, Mark Billinghurst
core  

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

open access: yesFEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer   +7 more
wiley   +1 more source

Is Familiarity Reflected in the Spatial Knowledge Revealed by Sketch Maps? [PDF]

open access: yes
Despite the frequent use of sketch maps in assessing environmental knowledge, it remains unclear how and to what degree familiarity impacts sketch map content.
Raubal, Martin; id_orcid   +7 more
core   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

Data augmentation-assisted deep learning of hand-drawn partially colored sketches for visual search.

open access: yesPLoS ONE, 2017
In recent years, image databases are growing at exponential rates, making their management, indexing, and retrieval, very challenging. Typical image retrieval systems rely on sample images as queries.
Jamil Ahmad   +2 more
doaj   +1 more source

Task-dependent sketch maps

open access: yesSpatial Cognition & Computation, 2023
Jakub Krukar   +2 more
openaire   +1 more source

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