Results 71 to 80 of about 2,541,137 (309)

Monte Carlo Localization in Hand-Drawn Maps

, 2015
Robot localization is a one of the most important problems in robotics. Most of the existing approaches assume that the map of the environment is available beforehand and focus on accurate metrical localization. In this paper, we address the localization
Agarwal, Pratik, Behzadian, Bahram, Burgard, Wolfram, Tipaldi, Gian Diego   +3 more
core   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

High-Quality Facial Photo-Sketch Synthesis Using Multi-Adversarial Networks

, 2018
Synthesizing face sketches from real photos and its inverse have many applications. However, photo/sketch synthesis remains a challenging problem due to the fact that photo and sketch have different characteristics. In this work, we consider this task as
Patel, Vishal M., Sindagi, Vishwanath A., Wang, Lidan   +2 more
core   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Guarantees for the Kronecker Fast Johnson-Lindenstrauss Transform Using a Coherence and Sampling Argument

, 2020
In the recent paper [Jin, Kolda & Ward, arXiv:1909.04801], it is proved that the Kronecker fast Johnson-Lindenstrauss transform (KFJLT) is, in fact, a Johnson-Lindenstrauss transform, which had previously only been conjectured.
Becker, Stephen, Malik, Osman Asif
core   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Proper Maps.

Interaction Design and Architecture(s)
GPS and digital mapping allow unprecedented accuracy, and the precision of digital storage has replaced the vagueness of the cartographer’s pencil.
Alan Dix
doaj   +1 more source

Individuals’ perceptions of areas exposed to coastal flooding in four French coastal municipalities: the contribution of sketch mapping

Geoenvironmental Disasters, 2018
Background This study analyzes individuals’ perceptions of areas exposed to coastal flooding at a local level using sketch mapping methodology. In this way, 318 individuals were surveyed in four coastal municipalities in France (Barneville-Carteret ...
Marie Coquet, Denis Mercier, Ghozlane Fleury-Bahi   +2 more
doaj   +1 more source

Rigidification of higher categorical structures

, 2016
Given a limit sketch in which the cones have a finite connected base, we show that a model structure of "up to homotopy" models for this limit sketch in a suitable model category can be transferred to a Quillen equivalent model structure on the category ...
Caviglia, Giovanni, Horel, Geoffroy
core   +2 more sources