Results 91 to 100 of about 564,148 (293)
FEBS Open Bio, EarlyView.The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida +6 more
wiley +1 more source
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
»Wir wollen Gesetze aufspüren«. Anton Weberns verworfene Skizzen zu einem dritten Satz der Symphonie op. 21 [PDF]
Zeitschrift der Gesellschaft für Musiktheorie, 2017 Marte Auer
doaj +1 more source
Sex and/or Gender? Some Neuroscientific Approache
Humana.Mente: Journal of Philosophical Studies, 2012 Traditionally, Gender Studies differentiates between the term “sex”, indicating sex differences from the biological point of view, and the term “gender”, indicating that sex differences are social and cultural constructions.
Valentina Chizzola
doaj
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
Thomas Ahrend / Matthias Schmidt (Hg.), Webern-Philologien (= Webern-Studien. Beihefte der Anton Webern Gesamtausgabe, Bd. 3), Wien: Lafite 2016 [PDF]
Zeitschrift der Gesellschaft für Musiktheorie, 2017 Ullrich Scheideler
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Hierarchical Schema Representation for Text-to-SQL Parsing With Decomposing Decoding
IEEE Access, 2019 Most of existing studies on parsing natural language (NL) for constructing structured query language (SQL) do not consider the complex structure of database schema and the gap between NL and SQL query.
Meina Song, Zecheng Zhan, Haihong E.
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Insights into designers’ sketching: a study of predictors of sketching behavior in design
Design ScienceAbstract Freehand sketching meets a vital need in design for fluid, fast and flexible visual representations that designers build off of and learn from. Sketching more frequently during the design process correlates with positive design outcomes. Engineering designers receive minimal training on freehand sketching, and engineering students do not ...
Morgan B. Weaver +2 more
openaire +1 more source
FEBS Open Bio, EarlyView.Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao +3 more
wiley +1 more source
Digital twins to accelerate target identification and drug development for immune‐mediated disorders
FEBS Open Bio, EarlyView.Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley +1 more source