Results 71 to 80 of about 42,468 (261)

»Wir wollen Gesetze aufspüren«. Anton Weberns verworfene Skizzen zu einem dritten Satz der Symphonie op. 21 [PDF]

Zeitschrift der Gesellschaft für Musiktheorie, 2017
Marte Auer
doaj   +1 more source

Sex and/or Gender? Some Neuroscientific Approache

Humana.Mente: Journal of Philosophical Studies, 2012
Traditionally, Gender Studies differentiates between the term “sex”, indicating sex differences from the biological point of view, and the term “gender”, indicating that sex differences are social and cultural constructions.
Valentina Chizzola
doaj  

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Thomas Ahrend / Matthias Schmidt (Hg.), Webern-Philologien (= Webern-Studien. Beihefte der Anton Webern Gesamtausgabe, Bd. 3), Wien: Lafite 2016 [PDF]

Zeitschrift der Gesellschaft für Musiktheorie, 2017
Ullrich Scheideler
doaj   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

Hierarchical Schema Representation for Text-to-SQL Parsing With Decomposing Decoding

IEEE Access, 2019
Most of existing studies on parsing natural language (NL) for constructing structured query language (SQL) do not consider the complex structure of database schema and the gap between NL and SQL query.
Meina Song, Zecheng Zhan, Haihong E.
doaj   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

50 years of Russian studies in Tromsø

Poljarnyj Vestnik: Norwegian Journal of Slavic Studies
In the fall semester of 1974, Associate Professor Ingvild Broch received the first four students of Russian at the University of Tromsø. In November 2024, we celebrated the first half century of Russian studies at our university, which is now known as ...
Tore Nesset
doaj   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source