Results 71 to 80 of about 42,550 (261)
Sex and/or Gender? Some Neuroscientific Approache
Traditionally, Gender Studies differentiates between the term “sex”, indicating sex differences from the biological point of view, and the term “gender”, indicating that sex differences are social and cultural constructions.
Valentina Chizzola
doaj
Estimating similarity and distance using FracMinHash
Motivation The increasing number and volume of genomic and metagenomic data necessitates scalable and robust computational models for precise analysis.
Mahmudur Rahman Hera, David Koslicki
doaj +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Thomas Ahrend / Matthias Schmidt (Hg.), Webern-Philologien (= Webern-Studien. Beihefte der Anton Webern Gesamtausgabe, Bd. 3), Wien: Lafite 2016 [PDF]
Ullrich Scheideler
doaj +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Hierarchical Schema Representation for Text-to-SQL Parsing With Decomposing Decoding
Most of existing studies on parsing natural language (NL) for constructing structured query language (SQL) do not consider the complex structure of database schema and the gap between NL and SQL query.
Meina Song, Zecheng Zhan, Haihong E.
doaj +1 more source
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
50 years of Russian studies in Tromsø
In the fall semester of 1974, Associate Professor Ingvild Broch received the first four students of Russian at the University of Tromsø. In November 2024, we celebrated the first half century of Russian studies at our university, which is now known as ...
Tore Nesset
doaj +1 more source
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source

