Results 71 to 80 of about 566,045 (292)

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Application of the Neutrosophic Fuzzy Sets in Profession Determination [PDF]

open access: yesNeutrosophic Sets and Systems
We present several operations, such as algebraic sum, algebraic product, and arithmetic mean, over the neutrosophic sets extended with moment in time and sketch numbers.
K. Rajesh   +3 more
doaj   +1 more source

Sketching Theoretical Frameworks for American Studies

open access: yesVNU Journal of Science: Education Research, 2018
This paper analyzes briefly the theoretical frameworks developed by major thinkers in American Studies (Alexis de Toccqueville, Israel Zangwill, Max Weber, Frederick Jackson Turner) and proposes a new theoretical framework that approaches to the USA as the biggest, earliest, and the most successful Special Free Economic Zone in the history. ...
openaire   +2 more sources

A Comparative Study on Face Sketch Synthesis

open access: yesIEEE Access, 2018
The purpose of face sketch synthesis technique is to generate a sketch from an input face image given a set of face sketch-photo images as the training set. Since face sketch synthesis is attracting huge attentions, an experimental study to existing methods is nontrivial.
Adeel Akram   +3 more
openaire   +2 more sources

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

High-Quality Facial Photo-Sketch Synthesis Using Multi-Adversarial Networks

open access: yes, 2018
Synthesizing face sketches from real photos and its inverse have many applications. However, photo/sketch synthesis remains a challenging problem due to the fact that photo and sketch have different characteristics. In this work, we consider this task as
Patel, Vishal M.   +2 more
core   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

Europa senza miti

open access: yesCambio, 2016
This article’s primary aim is to target (§2) a new terminological fashion in European studies, which tends to extol the alleged role of myths in the narrative about the European Union. This operation however requires first to provide a sketch (§1) of the
Furio Cerutti
doaj   +1 more source

Sketch-a-Net that Beats Humans

open access: yes, 2015
We propose a multi-scale multi-channel deep neural network framework that, for the first time, yields sketch recognition performance surpassing that of humans.
Hospedales, Timothy   +4 more
core   +1 more source

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

open access: yesMolecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy   +10 more
wiley   +1 more source

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