Results 61 to 70 of about 42,550 (261)
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
How to Do Things with Walter Benjamin
Lateral, 2020 Walter Benjamin is now a common reference point within cultural studies. But while a considerable secondary literature has emerged around his work, efforts to build upon his contributions by operationalizing the method they elaborate have remained ...
AK Thompson
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Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
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Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
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Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
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Doctor Honoris Causa granted by the Ricardo Palma university to Dr. Alfredo Quiñones Hinojosa
Revista de la Facultad de Medicina Humana, 2019 The Doctor Honoris Causa, is the highest honorary title granted by the Ricardo Palma University, to eminent persons. They are conferred with zeal by our house of studies to very outstanding personalities of the national and international scope, who with ...
Jhony Alberto De La Cruz Vargas
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Sketched Graph Drawing: A Lesson in Empirical Studies [PDF]
, 2013 This paper reports on a series of three similar graph drawing empirical studies, and describes the results of investigating subtle variations on the experimental method. Its purpose is two-fold: to report the results of the experiments, as well as to illustrate how easy it is to inadvertently make conclusions that may not stand up to scrutiny.
openaire +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
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»Wir wollen Gesetze aufspüren«. Anton Weberns verworfene Skizzen zu einem dritten Satz der Symphonie op. 21 [PDF]
Zeitschrift der Gesellschaft für Musiktheorie, 2017 Marte Auer
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