Results 101 to 110 of about 30,731 (301)

Self‐Assembling Hybrid Hydrogel Reprograms the Stromal Vascular Fraction to Treat Osteoarthritis

open access: yesAdvanced Science, EarlyView.
This study presents a bioinspired injectable hydrogel that enhances the therapeutic potential of stem cell‐rich stromal vascular fraction for treating osteoarthritis. By reprogramming cell behavior through epigenetic modulation, the hydrogel promotes cartilage regeneration and reduces joint damage in a rat model, offering a promising new approach for ...
Waifang Hou   +23 more
wiley   +1 more source

Multivariate Skew-Power-Normal Distributions: Properties and Associated Inference [PDF]

open access: gold, 2019
Guillermo Martínez‐Flórez   +2 more
openalex   +1 more source

Shape mixtures of multivariate skew-normal distributions

open access: yesJournal of Multivariate Analysis, 2009
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Arellano Valle, Reinaldo B.   +2 more
openaire   +11 more sources

Disruption of Treg Homeostasis in Rheumatoid Arthritis via Ferroptosis‐Mediated ETC Collapse and TXK‐STAT3/PLCγ1 Activation

open access: yesAdvanced Science, EarlyView.
In rheumatoid arthritis, synovial Tregs accumulate but are functionally impaired due to iron overload‐induced ferroptosis. This triggers mitochondrial dysfunction and TXK tyrosine kinase‐mediated signaling, leading to Treg destabilization and inflammation.
Jingrong Chen   +19 more
wiley   +1 more source

Classification Methods for the Serological Status Based on Mixtures of Skew-Normal and Skew-t Distributions

open access: yesMathematics
Gaussian mixture models are widely employed in serological data analysis to discern between seropositive and seronegative individuals. However, serological populations often exhibit significant skewness, making symmetric distributions like Normal or ...
Tiago Dias-Domingues   +2 more
doaj   +1 more source

Tumor‐Derived Exosomes Deliver Membrane‐Bound Fgl2 to Activate FcγRIIB‐Mediated Immunosuppression in Myeloid‐Derived Suppressor Cells

open access: yesAdvanced Science, EarlyView.
This study reveals that the Fgl2‐FcγRIIB signaling axis is a key mechanism by which MDSCs mediate tumor immune evasion. Tumor‐derived exosomes systemically activate MDSCs via this pathway, positioning this axis as a promising broad‐spectrum target for cancer immunotherapy.
Fenglin Lin   +12 more
wiley   +1 more source

ssmn: Skew Scale Mixtures of Normal Distributions [PDF]

open access: gold, 2016
Luis Benites Sanchez and Clecio da Silva Ferreira
openalex   +1 more source

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