Results 41 to 50 of about 14,405,507 (294)

A variational Bayesian approach for inverse problems with skew-t error distributions [PDF]

Journal of Computational Physics, 2015
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Guha, N, Wu, X, Efendiev, Y, Jin, B, Mallick, BK   +4 more
openaire   +4 more sources

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Stochastic Volatility Model with Leverage and Asymmetrically Heavy-tailed Error Using GH Skew Student's t-distribution [PDF]

Bayesian analysis of a stochastic volatility model with a generalized hyperbolic (GH) skew Student's t-error distribution is described where we first consider an asymmetric heavy-tailness as well as leverage effects. An efficient Markov chain Monte Carlo
Jouchi Nakajima, Yasuhiro Omori
core   +2 more sources

Construction and Applications of a Composite Model Based on Skew-Normal and Skew-t Distributions

Econometrics
Financial return distributions often exhibit central asymmetry and heavy-tailed extremes, challenging standard parametric models. We propose a novel composite distribution integrating a skew-normal center with skew-t tails, partitioning the support into ...
Jingjie Yuan, Zuoquan Zhang
doaj   +1 more source

Alpha-Skew Generalized t Distribution [PDF]

, 2015
The alpha-skew normal (ASN) distribution has been proposed recently in the literature by using standard normal distribution and a skewing approach. Although ASN distribution is able to model both skew and bimodal data, it is shortcoming when data has ...
Senoglu, Birdal, Arslan, Olcay, Acitas, Sukru   +2 more
core  

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Fitting Accumulated Stock Returns with Tempered Skew t-Distribution

Foundations
We analyze the distributions of historic S&P500 multi-day returns for the number of days of accumulation from 20 to 120. With the increase in the number of days of accumulation, we observe clear tempering of power-law tails toward a seemingly finite ...
Siqi Shao, Rostislav Serota
doaj   +1 more source

Applications of Skew Models Using Generalized Logistic Distribution

Axioms, 2016
We use the skew distribution generation procedure proposed by Azzalini [Scand. J. Stat., 1985, 12, 171–178] to create three new probability distribution functions.
Pushpa Narayan Rathie, Paulo Silva, Gabriela Olinto   +2 more
doaj   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source