Results 51 to 60 of about 44,265 (248)

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Modelling health scores with the skew-normal distribution [PDF]

, 2009
Health care interventions which use quality of life or health scores often provide data which are skewed and bounded. The scores are typically formed by adding up responses to a number of questions. Different questions might have different weights, but
Stanghellini, E., Hutton, Jane
core  

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Magnetic Circuit Analysis and Design Optimized for Cost-Effectiveness of Surface-Inserted Rare Earth Consequent-Pole Permanent Magnet Machines

Machines
In consequent-pole permanent magnet (CPPM) machines, the configuration where PM poles and iron poles are alternately arranged causes distortion in the air-gap magnetic field.
Li Wang, Muhammad Saqlain Saeed, Zhaoyang Fu, Jinglin Liu, Xiqiao Wu, Qi Wang   +5 more
doaj   +1 more source

Skew quantum Murnaghan-Nakayama rule [PDF]

Discrete Mathematics & Theoretical Computer Science, 2011
In this extended abstract, we extend recent results of Assaf and McNamara, the skew Pieri rule and the skew Murnaghan-Nakayama rule, to a more general identity, which gives an elegant expansion of the product of a skew Schur function with a quantum power
Matjaž Konvalinka
doaj   +1 more source

Obliquely propagating skew KP lumps

, 2016
Obliquely propagating skew lumps are studied within the framework of the Kadomtsev–Petviashvili equation with a positive dispersion (the KP1 equation). Specific features of such lumps are analysed in detail. It is shown that skew multi-lump solutions can
Stepanyants, Y., Singh, N.
core   +1 more source

The ubiquitin system in normal and infected germinal center B cells

FEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis, Lesly Mejia, Emily K Moser   +2 more
wiley   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source