Results 251 to 260 of about 433,672 (329)

Recent advances in the construction of humanized animal models and applications in translational medicine

Animal Models and Experimental Medicine, EarlyView.
Substantial advances have been achieved in the development of humanized mouse models, which have proven highly valuable in evaluating cancer immunotherapies and elucidating the mechanisms of infectious diseases. There is now a growing shift in research toward larger animal models—such as pigs—that offer greater physiological similarity to humans ...
Yanan Lyu, Yong‐Guang Yang, Zheng Hu
wiley   +1 more source

Three-dimensional deformation of strata that are rich with water during construction of a plane skew connecting channel using artificial ground freezing technique. [PDF]

Sci Rep
Hong R, Cai H, Yao Y.
europepmc   +1 more source

Speech Biomarkers for Quantifying Effects of Subthalamic Deep Brain Stimulation in Parkinson's Disease

Annals of Neurology, EarlyView.
Objective Dysarthria is one of the most common and disabling side effects of subthalamic nucleus deep brain stimulation (STN‐DBS) in Parkinson's disease (PD). Stimulation often exacerbates speech dysfunction beyond the effects of PD progression, likely because of current spread to structures surrounding the STN.
Petr Krýže, Mário Sousa, Vojtěch Illner, Adriana Jorge, Matilde Castelli, Ines Debove, Andreia D. Magalhães, Julia Waskönig, Lenard Lachenmayer, Joan Philipp Michelis, Gerd Tinkhauser, Deborah Amstutz, Marie Elise Maradan‐Gachet, Katrin Petermann, Claudio Pollo, Tobias Nef, Paul Krack, Jan Rusz   +17 more
wiley   +1 more source

Laser speckle flowgraph reveals dynamic characteristics and clinical relevance of choroidal watershed and peripapillary hypoperfusion zones. [PDF]

Sci Rep
Hashimoto R, Kardon RH.
europepmc   +1 more source

From Marginal to Central: Marginal Zone‐like B Cells as Critical Targets in Cladribine‐Treated Multiple Sclerosis

Annals of Neurology, EarlyView.
Objective Multiple sclerosis (MS) is a chronic autoimmune disease where B cells play a central pathogenic role. Cladribine, an oral therapy, provides durable benefits by reshaping lymphocyte populations, yet its specific long‐term impact on distinct B‐cell subsets is not fully understood.
Marta Pirronello, Mario Picozza, Gisella Guerrera, Silvia Corbisiero, Andrea Misiti, Roberta C. Placido, Alice Verdiani, Lorenzo de Marco, Manolo Sambucci, Elena Olivieri, Daniela F. Angelini, Esmeralda Quartuccio, Luca Prosperini, Carla Tortorella, Maria C. Buscarinu, Valeria Zancan, Francesca de Masi, Marco Salvetti, Claudio Gasperini, Giovanna Borsellino, Luca Battistini   +20 more
wiley   +1 more source

Linguistic Rule Generalisation Creates the Same Distributional Structure That Feeds It. [PDF]

Open Mind (Camb)
Pankratz E, Culbertson J, Kirby S.
europepmc   +1 more source

A stochastic daily weather generator for perennial crop simulations in tropical Malaysia. [PDF]

PLoS One
Teh CBS, Cheah SS, Appleton DR.
europepmc   +1 more source

Assessing the robustness of normality tests under varying skewness and kurtosis: a practical checklist for public health researchers. [PDF]

BMC Med Res Methodol
Kamath A, Poojari S, Varsha K.
europepmc   +1 more source

A Novel Mitochondrial Genome Resource for the Endemic Fish <i>Gymnodiptychus integrigymnatus</i> and Insights into the Phylogenetic Relationships of Schizothoracinae. [PDF]

Biology (Basel)
Li Y, Luo Y, Lv Y, Ou Y, Zhang R, Zhang R.   +5 more
europepmc   +1 more source