Results 91 to 100 of about 23,039 (217)
Smart Molecules, EarlyView.AI is transforming TPD by improving the design, prediction, and optimization of degraders such as PROTACs, molecular glues, and LYTACs. This review summarizes key AI‐driven advances, highlights applications across drug discovery stages, and discusses remaining challenges and future directions for accelerating the development of therapies against ...
Shuanglin Qin +10 more
wiley +1 more source
Five Decades of Dispute: A Triptych. E. J. Corey
The Chemical Record, EarlyView.In his 2004 Priestley Medal address, E. J. Corey stated, “On May 4, 1964, I suggested to my colleague R. B. Woodward a simple explanation involving the symmetry of the perturbed (HOMO) molecular orbitals for the stereoselective cyclobutene/1,3‐butadiene and 1,3,5‐hexatriene/cyclohexadiene conversions that provided the basis for the further development ...
Jeffrey I. Seeman
wiley +1 more source
Environmental Toxicology, EarlyView.ABSTRACT Anthropogenic activities generate a significant amount of pollutants that are released into the environment, causing physiological and ecological disturbances. Among the xenobiotics present in aquatic ecosystems, numerous chemical and organic compounds have oxidative potential or are metabolized through oxidative processes, which may amplify ...
Natália Eduarda da Silva +6 more
wiley +1 more source
A comparison of the UK's hot, dry summers of 1976 and 2025
Weather, EarlyView.Summer 2025 was the warmest so far recorded for the UK, and low precipitation amounts in preceding months and through the summer led to drought conditions in many areas of the UK. The hot, dry conditions prompted many comparisons with the infamous hot, dry summer of 1976.
Laura Baker
wiley +1 more source
World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.ABSTRACT Objectives To evaluate the clinical impact of anatomy‐based fitting (ABF) in cochlear implants for patients with asymmetric hearing loss. Study Design Prospective cohort study. Setting Tertiary referral center specializing in hearing disorders.
Andrea Canale +6 more
wiley +1 more source
The Responsibility of Zoos to Advance the Rights and Interests of Indigenous People
Zoo Biology, EarlyView.ABSTRACT The Earth is in its 6th mass extinction event, in 2022, in response to this crisis, 196 countries adopted the Kunming–Montreal Global Biodiversity Framework (GBF), a legally binding international agreement that aims to halt and reverse the trajectory of biodiversity loss by 2030.
Jack Pascoe, Sally Sherwen
wiley +1 more source
Reframing the Treasury Debate: Industrial Strategy and State Capacity in the UK
The Political Quarterly, EarlyView.Abstract The Treasury has long been seen as a root cause of Britain's economic malaise, blocking much‐needed industrial intervention and embedding short‐termism. This article examines the politics of Concorde and civil nuclear power in postwar Britain to show that the Treasury was not the problem in these cases.
Tom Kelsey
wiley +1 more source
Vog: Using Volcanic Eruptions to Estimate the Health Costs of Particulates
The Economic Journal, EarlyView., 2018 The negative consequences of long‐term exposure to particulate pollution are well established but a number of studies find no effect of short‐term exposure on health outcomes. The high correlation of industrial pollutants complicates the estimation of the impact of individual pollutants on health.
Timothy J. Halliday +2 more
wiley +1 more source
Barbara's Daughters: Women's Boxing and Social Memory in Britain
History, EarlyView.Abstract A pioneer of post‐war boxing, Barbara Buttrick fought in fairgrounds and on music‐hall stages in Britain and France before making a career in the United States during the 1950s. She fought against practical obstacles, prejudice and discrimination to become the Women's World Flyweight and Bantamweight Champion in 1957. This article examines her
Matthew Taylor
wiley +1 more source
International Journal of Urban and Regional Research, EarlyView.Abstract From desert ski resorts to subtropical Winter Games, there is a global proliferation of ‘mission‐impossible’ mega‐projects. The prevailing frameworks of city branding and urban entrepreneurism fail to explain the political logics behind these seemingly irrational projects.
Yiqiu Liu, Sven Daniel Wolfe
wiley +1 more source