Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Impact of the Practice of Playing Video Games on Technical Skills Development in Preclinical Dental Education: Preliminary Cross-Sectional Observational Study. [PDF]
Clouet R +5 more
europepmc +1 more source
RQ Labs: A Cybersecurity Workforce Skills Development Framework. [PDF]
Daniel C, Mullarkey M, Agrawal M.
europepmc +1 more source
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
Intergenerational effects of parental positive childhood experiences on social skills development in Chinese preschoolers: the moderating role of the home-rearing environment. [PDF]
Yuan X +7 more
europepmc +1 more source
Examining the impact of physical education and physical skills development on preschoolers' physical and mental health. [PDF]
Wang N +4 more
europepmc +1 more source
Developing Effective Communication Skills [PDF]
openaire +2 more sources
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
The effects of problem-based learning (PBL) on undergraduate medical students' critical thinking and communication skills development: A scoping review across resource-rich and resource-limited settings (2015-2024). [PDF]
Abugri BA +6 more
europepmc +1 more source
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris +10 more
wiley +1 more source

