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Current issues in uncomplicated skin and skin structure infections

Expert Review of Dermatology, 2007
Superficial skin infections caused by Staphylococcus aureus and Streptococcus pyogenes include primary infections, such as impetigo, and secondary infections, such as secondarily infected dermatitis or traumatic lesions. Such infections are some of the most common indications for antimicrobial therapy, with the particular choice of therapy depending on
Moise L Levy, Jeffrey M Weinberg
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Moxifloxacin

Drugs, 2002
Moxifloxacin is a fluoroquinolone antibacterial agent which attains good penetration into peripheral tissues and inflammatory fluids. The drug shows good in vitro activity against staphylococci and streptococci. Moxifloxacin is therefore a suitable option for the treatment of uncomplicated skin and skin structure infections of bacterial origin.
Richard B R, Muijsers, Blair, Jarvis
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Resistant pathogen-associated skin and skin-structure infections: antibiotic options

Expert Review of Anti-infective Therapy, 2010
Complicated skin and skin-structure infections (cSSSIs) are among the most common infections treated in the hospital setting. They are a significant clinical problem, partially owing to increasing resistance of infecting bacteria to current antibiotic therapies (nosocomial and community-acquired methicillin-resistant Staphylococcus aureus, extended ...
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Oritavancin: A Review in Acute Bacterial Skin and Skin Structure Infections

Drugs, 2015
Oritavancin (Orbactiv(®)) is a new generation lipoglycopeptide approved for use in adult patients with acute bacterial skin and skin structure infections (ABSSSI). It is administered as a single 1200 mg intravenous infusion over 3 h. In phase 3 trials in adult patients with ABSSSI, oritavancin was noninferior to vancomycin in terms of a composite ...
Yahiya Y, Syed, Lesley J, Scott
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The Role of Fluoroquinolones in Skin and Skin Structure Infections

American Journal of Clinical Dermatology, 2002
Skin and skin structure infections encompass a broad range of clinical presentations and disease severity. Antimicrobial therapy is clearly beneficial for both recovery from these infections as well as preventing disease progression. Fluoroquinolones are potent broad spectrum antimicrobial agents with the older agents characterized as having broad ...
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Bacterial Infections of the Skin and Skin Structures

2019
Skin and skin structure infections caused by bacteria involve the skin layers and underlying connective tissue. Cellulitis and abscess are two of the most common manifestations of these types of infections. Streptococcus pyogenes (group A streptococcus) is the predominant cause of cellulitis, but Staphylococcus aureus should also be considered.
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Staphylococcal infections of the skin and skin structures.

Cutis, 1986
A review of the pathogenesis, clinical manifestations, diagnosis, and therapy of staphylococcal skin and skin structure infections begins with discussion of the staphylococcal carrier state. Patients carrying Staphylococcus aureus are particularly vulnerable to infection if their skin is broken by wounds or placement of intravenous lines or catheters ...
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Treatment of skin and skin structure infections

The Pediatric Infectious Disease Journal, 1992
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Staphylococcus epidermidis and its dual lifestyle in skin health and infection

Nature Reviews Microbiology, 2022
Morgan M Brown, Alexander R Horswill
exaly  

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