Results 1 to 10 of about 7,168 (203)

Inference of ceftobiprole susceptibility through surrogate testing of ceftaroline [PDF]

Journal of Clinical Microbiology
Ceftobiprole is an advanced-generation cephalosporin active against methicillin-resistant Staphylococcus aureus and other clinically relevant bacteria.
Helio S. Sader, Rodrigo E. Mendes, David P. Nicolau, Kristie K. Zappas, Mariana Castanheira   +4 more
doaj   +2 more sources

Ceftaroline pharmacokinetics/pharmacodynamics in the hollow-fibre model of Mycobacterium abscessus lung disease [PDF]

IJTLD Open
BACKGROUND: Guideline-based therapy (GBT) of Mycobacterium abscessus (MAB) lung disease (LD) achieves a sputum culture conversion rate in ∼35% of patients. The β-lactam antibiotics, imipenem and cefoxitin, are the cornerstone of GBT.
B.E. Ferro, S. Srivastava, T. Gumbo
doaj   +2 more sources

Comparison of ceftriaxone versus ceftaroline in combination with ampicillin or penicillin against Enterococcus faecalis [PDF]

Microbiology Spectrum
Enterococcus faecalis infective endocarditis treatment with ampicillin plus ceftriaxone has not changed the mortality rates by over 30%. We identified borderline-penicillin-resistant, ampicillin-susceptible E.
Olivia Gladys Funk, Ruhma Khan, Zeel Shah, Jaclyn A. Cusumano   +3 more
doaj   +2 more sources

Susceptibility of Clinical Isolates of Staphylococcus aureus to Ceftaroline [PDF]

Journal of Clinical and Diagnostic Research, 2021
Introduction: Methicillin-Resistant Staphylococcus aureus (MRSA) infection is a major global healthcare problem, the prevalence of which varies from 25-50% in India.
Harsha Sreedharan, KB Asha Pai
doaj   +1 more source

Ceftaroline [PDF]

Revista Española de Quimioterapia, 2021
Community-acquired pneumonia (CAP) is one of the leading causes of admission to emergency departments. Ceftaroline is a fifth-generation cephalosporin with a potent In vitro activity against Streptococcus pneumoniae, Haemophilus influenzae and Staphylococcus aureus, the three most important pathogens causing CAP.
openaire   +2 more sources

In vitro susceptibility of ceftaroline against clinically important Gram-positive cocci, Haemophilus species and Klebsiella pneumoniae in Taiwan: Results from the Antimicrobial Testing Leadership and Surveillance (ATLAS) in 2012–2018

Journal of Microbiology, Immunology and Infection, 2021
Background/Purpose: Ceftaroline, with a unique activity against methicillin-resistant Staphylococcus aureus (MRSA), was not launched in Taiwan before 2019. The in vitro susceptibility data of ceftaroline against important Taiwanese pathogens are lacking.
Shio-Shin Jean, Wen-Sen Lee, Wen-Chien Ko, Po-Ren Hsueh   +3 more
doaj   +1 more source

Efficacy of ceftaroline and rifampin, alone or combined, in a rat model of methicillin-resistant Staphylococcus epidermidis osteomyelitis without implant

Microbiology Spectrum, 2023
The in vivo efficacy of ceftaroline and rifampin alone or in combination was investigated in an experimental rat model of methicillin-resistant Staphylococcus epidermidis (MRSE) osteomyelitis.
S. Albac, N. Anzala, D. Bonnot, H. Mirfendereski, P. Chavanet, D. Croisier   +5 more
doaj   +1 more source

Ceftaroline activity against Staphylococcus aureus isolated from patients with infective endocarditis, worldwide (2010–2019)

International Journal of Infectious Diseases, 2021
Objective: To evaluate the antimicrobial activity of ceftaroline against Staphylococcus aureus isolated from patients with infective endocarditis (IE). Methods: 23,833 S.
Helio S. Sader, Cecilia G. Carvalhaes, Rodrigo E. Mendes   +2 more
doaj   +1 more source

Spectrum and potency of ceftaroline against leading pathogens causing community-acquired respiratory tract and skin and soft tissue infections in Latin America, 2010

Brazilian Journal of Infectious Diseases, 2013
Ceftaroline, the active metabolite of the prodrug ceftaroline fosamil, is a cephalosporin with in vitro bactericidal activity against Gram-positive organisms, including methicillinsusceptible and -resistant Staphylococcus aureus, β-haemolytic and ...
Robert K. Flamm, Helio S. Sader, Ronald N. Jones   +2 more
doaj   +3 more sources

Systematic review of ceftaroline fosamil in the management of patients with methicillin-resistant Staphylococcus aureus pneumonia

European Respiratory Review, 2023
Methicillin-resistant Staphylococcus aureus (MRSA) is responsible for an array of problematic community- and healthcare-acquired infections, including pneumonia, and is frequently associated with severe disease and high mortality rates.
Antoní Torres, Alona Kuraieva, Gregory G. Stone, Catia Cillóniz   +3 more
doaj   +1 more source