Results 31 to 40 of about 5,163 (181)

In vitro activity of ceftaroline and comparators against bacterial isolates collected globally from patients with skin infections

Journal of Global Antimicrobial Resistance, 2021
: Objectives: This study reports the antimicrobial activities of ceftaroline and comparators against bacterial isolates from patients with skin and skin-structure infections (2015–2018).
Denis Piérard, Gregory G. Stone
doaj   +1 more source

In vitro activity of ceftaroline against bacterial pathogens isolated from patients with skin and soft tissue and respiratory tract infections in the Middle East and Africa: AWARE global surveillance programme 2015–2018

Journal of Global Antimicrobial Resistance, 2021
Objectives: To report antimicrobial susceptibility testing surveillance data for ceftaroline and comparative agents from the AWARE global surveillance programme for bacterial pathogens causing skin and soft tissue infections (SSTIs) and lower respiratory
James A. Karlowsky, Meredith A. Hackel, Samue l K. Bouchillon, Warren Lowman, Ramy El Mahdy Kotb, Naglaa Mohamed, Gregory G. Stone, Daniel F. Sahm   +7 more
doaj   +1 more source

Ceftaroline-Associated Encephalopathy: A Rare Adverse Effect

, 2021
In this case report, we present a patient who suffered ceftaroline-associated encephalopathy, while receiving ceftaroline for acute bacterial skin and skin structure infections (aBSSSIs) that resolved after cessation of the suspected agent.
Bennie, Blake, Kesavan, Ramesh, Srinivasan, Aswin, Viroliya, Krina, Sarva, Siva   +4 more
core   +1 more source

Ceftobiprole- and Ceftaroline-Resistant Methicillin-Resistant Staphylococcus aureus [PDF]

, 2015
The role of mecA mutations in conferring resistance to ceftobiprole and ceftaroline, cephalosporins with anti-methicillin-resistant Staphylococcus aureus (MRSA) activity, was determined with MRSA strains COL and SF8300.
Chan, Liana C, Chambers, Henry F, Chatterjee, Som S, Hamilton, Stephanie, Diep, Binh, Basuino, Li   +5 more
core   +1 more source

Multicenter Cohort Study of Ceftaroline Versus Daptomycin for Treatment of Methicillin-Resistant [PDF]

, 2022
BACKGROUND: Observational data suggest ceftaroline may be effective for methicillin-resistant Staphylococcus aureus (MRSA) bloodstream infection (BSI), but comparative data with standard of care are limited.
Davis, Susan L, Klinker, Kenneth P, Claeys, Kimberly C, Veve, Michael P, Sawyer, Adam J, Rybak, Michael J, Bhatia, Sahil, Levine, Donald P, Zasowski, Evan J, Huang, Vanthida, Kaye, Keith S, Trinh, Trang D, Lagnf, Abdalhamid M, Estrada, Sandy J, Johns, Scott T, LaFrance, Brandi   +15 more
core   +1 more source

Molecular Diversity and Comparison of Staphylococcal Cassette Chromosome <i>mec</i> Element in Hospital- and Community-Associated Methicillin-Resistant <i>Staphylococcus aureus</i> From Pakistan. [PDF]

Int J Microbiol
Background Methicillin‐resistant Staphylococcus aureus (MRSA) is one of the leading causes of hospital and community‐acquired infections, with the increasing threat of antimicrobial resistance worldwide. Staphylococcal Cassette Chromosome mec (SCCmec) typing is one of the molecular techniques to predict the genetic background of MRSA strains and ...
Ali A, Jabbar S, Aziz S, Riaz S.
europepmc   +2 more sources

In vitro activity of ceftaroline against mecC-positive MRSA isolates

, 2016
Ceftaroline is a new cephalosporin with activity against meticillin-resistant Staphylococcus aureus (MRSA). A collection of 17 clinical and veterinary mecC-positive MRSA isolates was tested to evaluate the in vitro efficacy of ceftaroline against ...
Rangstrup-Christensen, L., Shore, A.C., Bandt, D., Ehricht, R., Lazaris, A., Tenorio-Abreu, A., Gavier-Widen, D., Kinnevey, P., Monecke, S., Schlotter, K., Armengol-Porta, M., Hotzel, Helmut, Coleman, D.C., Peters, M.   +13 more
core   +2 more sources

Treatment outcomes of secondary bacteraemia in patients treated with ceftaroline fosamil: pooled results from six phase III clinical trials

Journal of Global Antimicrobial Resistance, 2022
: Objectives: This exploratory pooled analysis assessed the efficacy and safety of ceftaroline fosamil and comparators across six phase III clinical trials in adults with community-acquired pneumonia (CAP) or complicated skin and soft-tissue infection ...
Matthew Dryden, Michal Kantecki, Jean Li Yan, Gregory G. Stone, Heidi Leister-Tebbe, Mark Wilcox   +5 more
doaj   +1 more source

The use of extrapolation based on modeling and simulation to support high‐dose regimens of ceftaroline fosamil in pediatric patients with complicated skin and soft‐tissue infections

CPT: Pharmacometrics & Systems Pharmacology, 2021
A model‐informed drug development approach was used to select ceftaroline fosamil high‐dose regimens for pediatric patients with complicated skin and soft‐tissue infections caused by Staphylococcus aureus with a ceftaroline minimum inhibitory ...
Phylinda L.S. Chan, Lynn McFadyen, Andrea Quaye, Heidi Leister‐Tebbe, Victoria M. Hendrick, Jennifer Hammond, Susan Raber   +6 more
doaj   +1 more source

Comparing the Outcomes of Ceftaroline plus Vancomycin or Daptomycin Combination Therapy versus Vancomycin or Daptomycin Monotherapy in Adults with Methicillin-Resistant Staphylococcus aureus Bacteremia—A Meta-Analysis

Antibiotics, 2022
Introduction: Combination therapy with daptomycin plus ceftaroline to treat methicillin-resistant Staphylococcus aureus bacteremia has been reported to reduce methicillin-resistant Staphylococcus aureus bacteremia-related mortality.
Chienhsiu Huang, Ihung Chen, Lichen Lin
doaj   +1 more source