Scope and Predictive Genetic/Phenotypic Signatures of Bicarbonate (NaHCO3) Responsiveness and β-Lactam Sensitization in Methicillin-Resistant Staphylococcus aureus. [PDF]
, 2020 Addition of sodium bicarbonate (NaHCO3) to standard antimicrobial susceptibility testing medium reveals certain methicillin-resistant Staphylococcus aureus (MRSA) strains to be highly susceptible to β-lactams.
Bayer, Arnold S +12 more
core +1 more source
Antimicrobial susceptibility profiles of Staphylococcus aureus isolates recovered from humans, environmental surfaces, and companion animals in households of children with community-onset methicillin-resistant S. aureus infections [PDF]
, 2015 Our objective was to determine the antibiotic susceptibility profiles of Staphylococcus aureus isolates recovered from 110 households of children with community-onset methicillin-resistant S. aureus (MRSA) infections.
Burnham, Carey-Ann D +7 more
core +2 more sources
Efficacy and safety of ceftaroline: systematic review and meta-analysis
Therapeutic Advances in Infectious Disease, 2019 Background: Resistance to antibiotics is steadily increasing. Ceftaroline has a broad spectrum of activity against clinically relevant gram-positive strains including methicillin-resistant Staphylococcus aureus .
Maria T. Rosanova +3 more
doaj +1 more source
CPT: Pharmacometrics & Systems Pharmacology, 2021 A model‐informed drug development approach was used to select ceftaroline fosamil high‐dose regimens for pediatric patients with complicated skin and soft‐tissue infections caused by Staphylococcus aureus with a ceftaroline minimum inhibitory ...
Phylinda L.S. Chan +6 more
doaj +1 more source
An in vitro evaluation of the efficacy of tedizolid: implications for the treatment of skin and soft tissue infections [PDF]
, 2018 Skin and soft tissue infections (SSTI) are among the most commonly occurring infections and evidence suggests that these are increasing world-wide.
Aleryan, Muna +4 more
core +2 more sources
Journal of Global Antimicrobial Resistance, 2022 : Objectives: This exploratory pooled analysis assessed the efficacy and safety of ceftaroline fosamil and comparators across six phase III clinical trials in adults with community-acquired pneumonia (CAP) or complicated skin and soft-tissue infection ...
Matthew Dryden +5 more
doaj +1 more source
Role of cephalosporins in the era of Clostridium difficile infection [PDF]
, 2016 The incidence of Clostridium difficile infection (CDI) in Europe has increased markedly since 2000. Previous meta-analyses have suggested a strong association between cephalosporin use and CDI, and many national programmes on CDI control have focused on ...
Brogard +12 more
core +2 more sources
PLoS ONE, 2016 Fifth-generation cephalosporins, ceftobiprole and ceftaroline, are promising drugs for treatment of bacterial infections from methicillin-resistant Staphylococcus aureus (MRSA).
Alexander L Greninger +5 more
doaj +1 more source
Antibiotics, 2022 Introduction: Combination therapy with daptomycin plus ceftaroline to treat methicillin-resistant Staphylococcus aureus bacteremia has been reported to reduce methicillin-resistant Staphylococcus aureus bacteremia-related mortality.
Chienhsiu Huang, Ihung Chen, Lichen Lin
doaj +1 more source
Effective antibiotic conservation by emergency antimicrobial stewardship during a drug shortage [PDF]
, 2016 We present the first description of an antimicrobial stewardship program (ASP) used to successfully manage a multi-antimicrobial drug shortage. Without resorting to formulary restriction, meropenem utilization decreased by 69% and piperacillin-tazobactam
Casabar, Ed +8 more
core +2 more sources