Results 11 to 20 of about 7,168 (203)

Characterizing the role of porin mutations in susceptibility of beta lactamase producing Klebsiella pneumoniae isolates to ceftaroline and ceftaroline-avibactam

International Journal of Infectious Diseases, 2020
Objectives: Evaluate the role of porins in the susceptibility of Klebsiella pneumoniae to ceftaroline and ceftaroline-avibactam. Methods: Susceptibility to ceftaroline and ceftaroline-avibactam was tested by broth microdilution method in Klebsiella ...
Ali Khalid, Alicia Fajardo Lubián, Li Ma, Ruby C.Y. Lin, Jonathan R. Iredell   +4 more
doaj   +1 more source

Ceftaroline In-vitro Activity against Methicillin Resistant Staphylococcal Isolates in a Rural Tertiary Health Care Centre [PDF]

National Journal of Laboratory Medicine, 2021
Introduction: The emergence of Methicillin Resistant (MR) staphylococcal infections had led to fewer therapeutic options. Ceftaroline fosamil is the only cephalosporin approved by United States of America (USA) Food and Drug Administration (FDA) till
VIJAYA SHIVANNA, SS PRAJWAL, D VENKATESHA   +2 more
doaj   +1 more source

Use of Ceftaroline in Hospitalized Patients with and without COVID-19: A Descriptive Cross-Sectional Study

Antibiotics, 2021
A single-center cross-sectional study was conducted to describe the use of ceftaroline in a large teaching hospital in Northern Italy, during a period also including the first months of the coronavirus disease 2019 (COVID-19) pandemic.
Daniele Roberto Giacobbe, Chiara Russo, Veronica Martini, Silvia Dettori, Federica Briano, Michele Mirabella, Federica Portunato, Chiara Dentone, Sara Mora, Mauro Giacomini, Marco Berruti, Matteo Bassetti   +11 more
doaj   +1 more source

Evaluating the antibacterial activity of ceftaroline against clinical isolates of methicillin-susceptible and- resistant Staphylococcus aureus in Kuwait hospitals

Journal of Infection and Public Health, 2020
Ceftaroline fosamil has been approved by the US Food and Drug Administration for the treatment of skin and soft tissue infections, including those caused by methicillin-resistant Staphylococcus aureus and community-acquired bacterial pneumonia.
Wadha Alfouzan, Samar S. Boswihi, Rita Dhar, Edet Udo   +3 more
doaj   +1 more source

Evaluation of in vitro activity of ceftaroline against pathogens associated with community-acquired pneumonia: ATLAS program 2017–2019

Journal of Global Antimicrobial Resistance, 2023
: Objectives: Ceftaroline is an important therapeutic option for community-acquired pneumonia (CAP). Antimicrobial susceptibility to ceftaroline and other antimicrobial agents against Staphylococcus aureus, Streptococcus pneumoniae, and Haemophilus ...
Eric Utt, Michal Kantecki, Guillermo Cabezas-Camarero, Susanna Esposito   +3 more
doaj   +1 more source

When good bugs go bad: Epidemiology and antimicrobial resistance profiles of Corynebacterium striatum, an emerging multidrug-resistant, opportunistic pathogen [PDF]

, 2017
Infections with Corynebacterium striatum have been described in the literature over the last 2 decades, with the majority being bacteremia, central line infections, and occasionally, endocarditis.
Anderson, Neil, Burnham, Carey-Ann D, McMullen, Allison R, Shupe, Angela, Wallace, Meghan A   +4 more
core   +2 more sources

PBP4: A New Perspective on Staphylococcus aureus β-Lactam Resistance. [PDF]

, 2018
β-lactam antibiotics are excellent drugs for treatment of staphylococcal infections, due to their superior efficacy and safety compared to other drugs.
Chambers, Henry F, Chatterjee, Som S, da Costa, Thaina M, de Oliveira, Carolina R   +3 more
core   +3 more sources

In vitro activity of ceftaroline against bacterial pathogens isolated from patients with skin and soft tissue and respiratory tract infections in the Middle East and Africa: AWARE global surveillance programme 2015–2018

Journal of Global Antimicrobial Resistance, 2021
Objectives: To report antimicrobial susceptibility testing surveillance data for ceftaroline and comparative agents from the AWARE global surveillance programme for bacterial pathogens causing skin and soft tissue infections (SSTIs) and lower respiratory
James A. Karlowsky, Meredith A. Hackel, Samue l K. Bouchillon, Warren Lowman, Ramy El Mahdy Kotb, Naglaa Mohamed, Gregory G. Stone, Daniel F. Sahm   +7 more
doaj   +1 more source

Impact of time to appropriate therapy on mortality in patients with vancomycin-intermediate Staphylococcus aureus infection [PDF]

, 2016
Despite the increasing incidence of vancomycin-intermediate Staphylococcus aureus (VISA) infections, few studies have examined the impact of delay in receipt of appropriate antimicrobial therapy on outcomes in VISA patients.
Burnham, Carey-Ann D, Burnham, Jason P, Kollef, Marin H, Warren, David K   +3 more
core   +2 more sources

Effects of Subinhibitory Concentrations of Ceftaroline on Methicillin-Resistant Staphylococcus aureus (MRSA) Biofilms.

PLoS ONE, 2016
Ceftaroline (CPT) is a novel cephalosporin with in vitro activity against Staphylococcus aureus. Ceftaroline exhibits a level of binding affinity for PBPs in S. aureus including PBP2a of methicillin-resistant S. aureus (MRSA). The aims of this study were
María Lázaro-Díez, Sara Remuzgo-Martínez, Cristina Rodríguez-Mirones, Felix Acosta, Jose M Icardo, Luis Martínez-Martínez, José Ramos-Vivas   +6 more
doaj   +1 more source