Results 41 to 50 of about 7,168 (203)

Risk of Acute Kidney Injury Associated With Nephrotoxic Burden in Hospitalized Patients: A Scoping Review

Clinical Pharmacology &Therapeutics, Volume 119, Issue 4, Page 891-904, April 2026.
Limited evidence exists synthesizing the risk of acute kidney injury (AKI) associated with the concomitant administration of multiple nephrotoxic drugs, and even less examining the concept of nephrotoxic burden. The objective of this scoping review was to (1) identify definitions of nephrotoxic burden; (2) methods used to quantify (use of calculations)
Wafa Alatawi, Jessica L. Wallace, Dhakrit Rungkitwattanakul, Britney A. Stottlemyer, Tiffany L. Tran, Melanie Manis Reida, Sandra L. Kane‐Gill   +6 more
wiley   +1 more source

Of Commensals and Opportunists: Genomics of Coagulase‐Negative Staphylococci During Sequential Ear and Eye Infections in a Healthy Adult

MicrobiologyOpen, Volume 15, Issue 2, April 2026.
The genomes of coagulase‐negative staphylococci (CoNS) isolated during sequential ear and eye infections in a healthy adult are analyzed. We highlight the identification of a community‐acquired S. capitis subsp. urealyticus ST1 lineage carrying a mosaic SCCmec IV element, linking common skin commensals to multidrug‐resistant strains associated with ...
Soo Sum Lean, Chew Chieng Yeo, Zain Illyaaseen, Sargit Kaur, Yun Fong Ngeow, Stuart C. Clarke, Hien Fuh Ng   +6 more
wiley   +1 more source

In Vitro Activity of Ceftaroline and Comparators against Bacterial Isolates Collected Globally from Patients with Skin and Soft Tissue Infections: ATLAS Program 2019–2020

Antibiotics, 2023
The objective of this study was to assess the in vitro activity of ceftaroline and a panel of comparator agents against isolates causing skin and soft tissue infections (SSTIs) collected in Africa/Middle East, Asia–Pacific, Europe, and Latin America from
Alona Kuraieva, Guillermo Cabezas-Camarero, Pattarachai Kiratisin, Eric Utt   +3 more
doaj   +1 more source

A Retrospective Analysis of Treatment and Clinical Outsomes among Patients with Methicillin-Susceptible \u3cem\u3eStaphlococcus aureus\u3c/em\u3e Bloodstream Isolates Possessing detecable mecA by a Commercial PCR Assay Compared to Patients with Methicillin-Resistant \u3cem\u3eStaphylococcus aureus\u3c/em\u3e Bloodstream Isolates [PDF]

, 2018
mecA-positive Staphylococcus aureus isolates phenotypically susceptible to cefoxitin (mecA-methicillin-sensitive S. aureus[MSSA]) have been identified. We describe the treatment and outcomes among patients with mecA-MSSA bloodstream infections (BSI) and ...
Dilworth, Thomas J., Elshaboury, Ramy, Jones, Dylan, Munson, Erik   +3 more
core   +1 more source

Staphylococcal cassette chromosome mec typing and meca sequencing in methicillin-resistant staphylococci from Algeria: A highly diversified element with new mutations in mecA [PDF]

, 2016
Genetic mechanisms of methicillin resistance are still relevant in staphylococci. The aims of this study are to assess the possible exchanges of staphylococcal cassette chromosome mec (SCCmec) among isolates of methicillin-resistant staphylococci (MRS ...
Aleo, A., Benallaoua, S., Bonura, C., Djoudi, F., Mammina, C., Touati, A.   +5 more
core   +1 more source

Bacterial Profiling and Antibiotic Resistance Pattern of Uropathogens Isolated From Adolescent Girls With Bacteriuria: A Cross‐Sectional Study

Health Science Reports, Volume 9, Issue 3, March 2026.
ABSTRACT Background and Aims Urinary tract infections (UTIs) are prevalent among adolescent girls. Therefore, effective promotional campaigns are crucial for conveying accurate information. This study aimed to assess the prevalence and the antimicrobial profiling of the isolated uropathogens among 354 adolescent girls. Methods This is a cross‐sectional
Shimaa Abdelrahim Khalaf, Mona Gamal Mohamed, Amal A. Elkhawaga, Iftekhar Ahmed, Md. Rabiul Islam, Shaimaa M. Goda   +5 more
wiley   +1 more source

Simultaneous Bilateral Endobronchial Valve Insertion for Management of Persistent Air Leaks Secondary to Necrotising Pneumonia

Respirology Case Reports, Volume 14, Issue 3, March 2026.
This report details a rare case of bilateral PAL secondary to necrotising pneumonia in a critically ill patient, successfully managed with simultaneous bilateral endobronchial valves placement, highlighting the feasibility and clinical efficacy of this approach.
Jelena Solujic, Michael Brown, Phan Nguyen, Arash Badiei   +3 more
wiley   +1 more source

Activity of ceftaroline and comparators against pathogens isolated from skin and soft tissue infections in Latin America – results of AWARE surveillance 2012

Brazilian Journal of Infectious Diseases, 2015
As part of the Assessing Worldwide Antimicrobial Resistance Evaluation (AWARE) surveillance program in 2012 the in vitro activity of ceftaroline and relevant comparator antimicrobials was evaluated in six Latin American countries (Argentina, Brazil ...
Daryl Hoban, Douglas Biedenbach, Daniel Sahm, Edina Reiszner, Joseph Iaconis   +4 more
doaj   +1 more source

Quantification of Ceftaroline in Human Plasma Using High-Performance Liquid Chromatography with Ultraviolet Detection: Application to Pharmacokinetic Studies

Pharmaceutics, 2021
This study was conducted to develop a rapid, simple and reproducible method for the quantification of ceftaroline in plasma samples by high-performance liquid chromatography with ultraviolet detection (HPLC-UV).
Ana Alarcia-Lacalle, Helena Barrasa, Javier Maynar, Andrés Canut-Blasco, Carmen Gómez-González, María Ángeles Solinís, Arantxazu Isla, Alicia Rodríguez-Gascón   +7 more
doaj   +1 more source

Phenotypic and Genotypic Analyses of Antimicrobial Resistance Patterns of Staphylococcus aureus Isolates From Outpatient Blood Samples in Mukuru Slum, Nairobi, Kenya

Canadian Journal of Infectious Diseases and Medical Microbiology, Volume 2026, Issue 1, 2026.
Background Bloodstream infections caused by Staphylococcus aureus (S. aureus) and its methicillin‐resistant S. aureus (MRSA) represent a major clinical challenge, contributing to prolonged illness, increased healthcare costs, and high mortality worldwide. In low‐resource settings, these infections are further aggravated by overcrowding, poor sanitation,
Jeremiah Ogeto, Simon Mitema, Gabriel Aboge, Alfred Mainga, Gervason Moriasi, Mian Muhammad Awais   +5 more
wiley   +1 more source