Results 61 to 70 of about 5,163 (181)
Ceftaroline fosamil doses and breakpoints for Staphylococcus aureus in complicated skin and soft tissue infections [PDF]
Objectives To describe the pharmacokinetic/pharmacodynamic (PK/PD) modelling and microbiological data that were used to support the recent European approval of ceftaroline fosamil 600 mg q8h by 2 h intravenous (iv) infusion for patients with complicated ...
Li, J +6 more
core +1 more source
Objective: The objective of this review is to describe the outcomes of patients treated with ceftaroline in the non-Food and Drug Administration (FDA) approved indication of methicillin-resistant Staphylococcus aureus (MRSA) infections in both pediatric ...
Nicole Lounsbury +3 more
doaj +1 more source
Antibiotic Use in Livestock: A Driver of Resistance in Africa and the Path to Safer Alternatives
The incorporation of antibiotics into animal feeds is one of the drivers of antibiotic resistance, a global One Health challenge. To reduce the burden of antibiotic resistance, the use of alternative growth promoters and drugs must be promoted, as well as sensitization and implementation of regulations.
Mercy A. Alabi +2 more
wiley +1 more source
Population Pharmacokinetic Modeling and Probability of Target Attainment Analyses in Asian Patients With Community-Acquired Pneumonia Treated With Ceftaroline Fosamil [PDF]
Efficacy of ceftaroline fosamil, the prodrug of the active metabolite ceftaroline, was demonstrated in a phase 3 study of hospitalized Asian patients with Pneumonia Outcomes Research Team (PORT) risk class III–IV community-acquired pneumonia (NCT01371838)
Nidal Al‐Huniti +7 more
core +1 more source
Matrix‐Assisted Pulsed Laser Evaporation (MAPLE) technique is used to cover titanium (Ti) substrates with multifunctional bioactive coatings composed of bioglass, vitamin D3, and melittin. Coatings exhibited excellent chemical integrity and favorable micro/nanostructured morphology (promoting cellular adhesion and viability), and a sustained release of
Irina Negut +9 more
wiley +1 more source
Effects of ceftaroline on biofilm formation.
Biofilm formation by MRSA in presence of ceftaroline, in 24-well polystyrene plates after 48 h, assessed by crystal violet staining. Each bar indicates the mean values ± SE from four independent experiments. Strains 06/1483, 05/2369, 05/3291 were tested.
José Ramos-Vivas (847494) +6 more
core +1 more source
Background: The increase in methicillin-resistant Staphylococcus aureus (MRSA)-related pyogenic infections emphasizes the need for new treatment options.
Swati Saxena +4 more
doaj +1 more source
Antibiotic Resistance: A Genetic and Physiological Perspective
The development of resistance to antimicrobials and their historical progression are depicted in this graphic. It draws attention to important biochemical, physiological, and genetic factors that contribute to AMR, such as the transmission of genes, the development of biofilms, and the inactivation of antibiotics.
Rania G. Elbaiomy +9 more
wiley +1 more source
Discrepancies in Beta‐Lactam Antibiotics Cross‐Reactivity: Implications for Clinical Practice
Four studies previously published on beta‐lactam antibiotics cross‐reactivity were compared head‐to‐head. These studies covered 51 antibiotics, theoretically leading to 2550 potential recommendations regarding alternatives in case of specific allergies. The studies analysed different sets of beta‐lactam antibiotics.
Evelien Maria Hutten +4 more
wiley +1 more source
Christy Maggiore,1 Jose A Vazquez,2 David J Guervil,3 Ananthakrishnan Ramani,4 Alena Jandourek,5 Phillip Cole,5 H David Friedland5 1Gulf Coast Medical Center, Panama City, FL, USA; 2Medical College of Georgia, Georgia Regents University, Augusta, GA ...
Cole P +7 more
core

