Results 81 to 90 of about 5,163 (181)

Activity of chequerboard combinations of ceftaroline and NXL104 versus β-lactamase-producing Enterobacteriaceae

, 2010
Background Ceftaroline is a novel oxyimino-cephalosporin, strongly active against methicillin-resistant staphylococci and pneumococci. It is active against Enterobacteriaceae too, but is labile to common ß-lactamases, including AmpC and extended-spectrum
Warner, M., Williams, G., Livermore, DM, Mushtaq, S., Critchley, I.   +4 more
core   +1 more source

A Randomized, Prospective Study of Pediatric Patients With Community-acquired Pneumonia Treated With Ceftaroline Versus Ceftriaxone

, 2018
Background: Community-acquired bacterial pneumonia (CABP) remains a major infection among children, despite the use of pneumococcal vaccination. Ceftaroline fosamil is a broad-spectrum cephalosporin antibiotic with activity against many bacteria ...
Cannavino CR, Bradley JS, Friedland HD, Kaplan SL, O'Neal T, Németh Ágnes, Jandourek A, Korczowski B   +7 more
core   +1 more source

Ceftaroline fosamil salvage therapy : an option for reduced-vancomycin-susceptible MRSA bacteraemia

, 2015
Objectives To examine the activity of ceftaroline against reduced-vancomycin-susceptible MRSA isolates. Methods One-hundred and three MRSA blood culture isolates (predominantly ST239-MRSA-III), with varying vancomycin phenotypes, had their ceftaroline ...
Jensen, Slade O. (R16034), Espedido, Bjorn (R16206), Hal, Sebastiaan J. van (R17037)   +2 more
core   +1 more source

Ceftaroline Desensitization Procedure in a Pregnant Patient With Multiple Drug Allergies

, 2015
Validated skin testing is lacking for many drugs, including ceftaroline. The cross-reactivity between ceftaroline and other β-lactam antibiotics is unknown.
Weil, Ana, Varughese, Christy A., Balekian, Diana S., Blumenthal, Kimberly, Banerji, Aleena, Seiguer Shenoy, Erica, Sokol, Caroline, Kuhlen, James L.   +7 more
core   +1 more source

Ceftaroline, an Update

, 2018
Objective: The objective of this review is to describe the outcomes of patients treated with ceftaroline in non-Food and Drug Administration (FDA) approved indications in pediatric or adult populations with infections caused by MRSA. Data sources: A systematic overview was conducted by searching PubMed, Medline, and The Cochrane Library up to October ...
Nicole Lounsbury, Mary Reeber, Georges Mina, Christiane Chbib   +3 more
openaire   +1 more source

Multistep Resistance Development Studies of Ceftaroline in Gram-Positive and -Negative Bacteria

, 2011
Ceftaroline, the active component of the prodrug ceftaroline fosamil, is a novel broad-spectrum cephalosporin with bactericidal activity against Gram-positive and -negative isolates.
Klaudia Kosowska-Shick, Pamela McGhee, Catherine Clark, Peter C. Appelbaum   +3 more
core   +1 more source

IN VITRO SUSCEPTIBILITY OF MRSA CLINICAL ISOLATES TO CEFTAROLINE

Pakistan Armed Forces Medical Journal, 2018
Objective: To determine the in vitro susceptibility of MRSA clinical isolates to ceftaroline, using interpretation of zones of inhibition by disk diffusion method. Study Design: Descriptive cross sectional.
Muhammad Aurangzeb, Raja Kamran Afzal, Muhammad Abid, Aamir Hussain, Fauzia Aitazaz, Rozina Khaliq   +5 more
doaj   +4 more sources

In vitro Activity of Ceftaroline Against Isolates of Gram-Positive Bacteria from Patients with Bloodstream Infections Collected as a Part of ATLAS Between 2017 and 2020

Marie Kempf,1,2 Francis F Arhin,3 Alona Kuraieva,4 Eric Utt5 1Laboratory of Bacteriology, University Hospital Angers, Angers, France; 2INCIT, Inserm, CHU Angers, Univ Angers, Nantes Université, Angers, F-49000, France; 3Pfizer Inc, Kirkland, Quebec ...
Arhin FF, Kuraieva A, Kempf M, Utt E
core  

Rate and Incidence of Adverse Reactions Associated With Ceftaroline Exposure: Importance of Cutaneous Manifestations

, 2017
Background: Ceftaroline is a broad-spectrum, methicillin-resistant Staphylococcus aureus (MRSA)-active β-lactam approved for acute bacterial skin and skin structure infections (ABSSSIs) and community-acquired pneumonia. Because of its favorable spectrum
Ryan P. Moenster, Moenster, Ryan P., Jansen, Jeffrey W., Jeffrey W. Jansen   +3 more
core   +1 more source

Immunomodulatory role of ceftaroline in monocytes and macrophages.

, 2016
Cigarette smoke is the principal risk factor for chronic obstructive pulmonary disease (COPD) and can negatively influence the effectiveness of the immune system's response to a pathogen.
Pace E, Dino P, Di Gaudio F, Gjomarkaj M, Siena L, Di Vincenzo S, Cipollina C, Bruno A   +7 more
core   +1 more source