Results 81 to 90 of about 7,168 (203)

Targeting antibiotic resistance [PDF]

, 2016
Finding strategies against the development of antibiotic resistance is a major global challenge for the life sciences community and for public health.
Chellat, Mathieu F., Raguž, Luka, Riedl, Rainer   +2 more
core   +1 more source

Epidemiology, Treatment, and Outcomes of Gram‐Negative Bacteremia in a Multicenter Cohort of Solid Organ Transplant Recipients

Clinical Transplantation, Volume 39, Issue 4, April 2025.
ABSTRACT Introduction Little is known about the epidemiology and management of gram‐negative bloodstream infections (GN‐BSIs) in patients after solid organ transplant (SOT). We describe epidemiology, treatment approaches, and outcomes in a subset of patients with SOT from a larger cohort with GN‐BSI. Methods This was a multicenter, retrospective cohort
Sarah B. Doernberg, Emily L. Heil, Suiyini Fiawoo, Jae Hyoung Lee, Sara E. Cosgrove, David M. Dobrzynski, Yihan Li, Ryan K. Shields, Emily S. Spivak, Erica J. Stohs, Pranita D. Tamma, Erin K. McCreary   +11 more
wiley   +1 more source

Establishing discordance rate of estimated glomerular filtration rate between serum creatinine‐based calculations and cystatin‐C‐based calculations in critically ill patients

Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, Volume 45, Issue 3, Page 161-168, March 2025.
Abstract Introduction The use of serum creatinine (SCr) for drug dosing has significant limitations and is influenced by many non‐kidney factors. Cystatin C (cysC) is an alternative or additional marker of kidney function that is less affected by non‐kidney factors. Although cysC may be useful in hospitalized patients, the use of cysC to calculate drug
Victoria L. Williams, Anthony T. Gerlach
wiley   +1 more source

Antimicrobial options for methicillin-resistant Staphylococcus aureus pyogenic infections: an in vitro comparison of ceftaroline, vancomycin, and linezolid

MGM Journal of Medical Sciences
Background: The increase in methicillin-resistant Staphylococcus aureus (MRSA)-related pyogenic infections emphasizes the need for new treatment options.
Swati Saxena, Manodeep Sen, Jyotsna Agarwal, Anupam Das, Vikramjeet Singh   +4 more
doaj   +1 more source

Veterinary Medicine Needs New Green Antimicrobial Drugs [PDF]

, 2016
Given that: (1) the worldwide consumption of antimicrobial drugs (AMDs) used in food-producing animals will increase over the coming decades; (2) the prudent use of AMDs will not suffice to stem the rise in human antimicrobial resistance (AMR) of animal ...
Adams, Aidara-Kane, Alvarez, Amidon, Andersson, Andremont, Andremont, Angulo, Ashbolt, Baquero, Bednorz, Bibbal, Bonomo, Brunton, Call, Centers for Disease Control and Prevention, Chantziaras, Chen, Cheng, Cheng, Collignon, DANMAP, de Jong, Dewulf, Duse, Dutil, Edlung, European Food Safety Authority, European Food Safety Authority, European Food Safety Authority, European Medicine Agency, European Medicines Agency, European Medicines Agency, Fairbrother, Food and Drug Administration, Foster, Hansen, Herrick, Heuer, Hofmann, Hojberg, Holman, Horowitz, Huang, Ito, Jacobsen, Kusama, Langlois, Lindecrona, Lipinski, Lipinski, Luo, Marshall, Metz, Midtlyng, Montanari, Naess, Nielsen, Nord, O’Brien, O’Connor, Panagiotidis, Phillips, Pijpers, Pollet, Rashid, Rashid, Ratz, Rioux, Roof, Rose, Sakaeda, Sarmah, Singer, Smith, Sparo, Stamey, Subbiah, Takenouchi, Taverne, Thiele-Bruhn, Tolls, Toutain, Toutain, Toutain, Toutain, Toutain, Trobos, Van Boeckel, van den Bogaard, van der Waaij, Wellington, Whitman, World Health Organisation, World Health Organisation, Yazdankhah, Yusof, Zhang   +97 more
core   +5 more sources

Complicated and deep bacterial skin and soft tissue infections

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, Volume 23, Issue 3, Page 357-375, March 2025.
Summary Complicated erysipelas, cellulitis, and necrotizing soft tissue infections belong to the spectrum of bacterial infections affecting the skin and underlying soft tissues. Their frequency as well as risk of recurrence and complicated disease course pose a significant health burden.
Christine Prodinger, Arno Lechner, Arno Hintersteininger, Jan Marco Kern, Matthias Meißnitzer, Damian Meyersburg, Johann W. Bauer, Martin Laimer   +7 more
wiley   +1 more source

Bicarbonate Resensitization of Methicillin-Resistant Staphylococcus aureus to β-Lactam Antibiotics. [PDF]

, 2019
Endovascular infections caused by methicillin-resistant Staphylococcus aureus (MRSA) are a major health care concern, especially infective endocarditis (IE).
Abdelhady, Wessam, Bayer, Arnold S, Chambers, Henry F, Ersoy, Selvi C, Li, Liang, Xiong, Yan Q   +5 more
core  

Beyond conventional antibiotics for the future treatment of methicillin-resistant Staphylococcus aureus infections: two novel alternatives. [PDF]

, 2012
The majority of antibiotics currently used to treat methicillin-resistant Staphylococus aureus (MRSA) infections target bacterial cell wall synthesis or protein synthesis. Only daptomycin has a novel mode of action.
Devocelle, Marc, Fitzgerald-Hughes, Deirdre, Humphreys, Hilary   +2 more
core   +1 more source

Addition of ceftaroline fosamil or vancomycin to PMMA: An in vitro comparison of biomechanical properties and anti-MRSA efficacy

Journal of Orthopaedic Surgery, 2019
Background: Ceftaroline is a cephalosporin that is effective against methicillin-resistant Staphylococcus aureus (MRSA) infections. The objective of this study was to determine the feasibility of using ceftaroline-loaded Polymethyl methacrylate (PMMA) as
Amber Haseeb, Vivek Ajit Singh, Cindy Shuan Ju Teh, Mun Fai Loke   +3 more
doaj   +1 more source

Antimicrobial Resistance (AMR) and Multidrug Resistance (MDR): Overview of Current Approaches, Consortia and Intellectual Property Issues [PDF]

, 2017
The supply of new diagnostics and treatments is insufficient to keep up with the increase in antimicrobial resistance (AMR) and multidrug resistance (MDR) as older medicines are used more widely and microbes develop resistance to them.
Bhagwandin, Niresh, Jenner, Andrew, Kowalski, Stanley P.   +2 more
core   +1 more source