Results 71 to 80 of about 7,168 (203)

A case of idiosyncratic drug‐induced agranulocytosis because of sulbactam/ampicillin

open access: yesJournal of General and Family Medicine, Volume 26, Issue 5, Page 479-484, September 2025.
We report a case of agranulocytosis caused by sulbactam/ampicillin. During antimicrobial therapy, close monitoring of total white blood cell counts is essential. Abstract Idiosyncratic drug‐induced agranulocytosis is a rare but life‐threatening condition that requires immediate medical intervention.
Kazuya Toda   +4 more
wiley   +1 more source

A Mini-Review on Ceftaroline in Bacteremia Patients with Methicillin-Resistant Staphylococcus aureus (MRSA) Infections

open access: yesAntibiotics, 2019
Objective: The objective of this review is to describe the outcomes of patients treated with ceftaroline in the non-Food and Drug Administration (FDA) approved indication of methicillin-resistant Staphylococcus aureus (MRSA) infections in both pediatric ...
Nicole Lounsbury   +3 more
doaj   +1 more source

Phenotypic and Genotypic Characteristics of Methicillin-Resistant Staphylococcus aureus (MRSA) Related to Persistent Endovascular Infection. [PDF]

open access: yes, 2019
Persistent methicillin-resistant Staphylococcus aureus (MRSA) bacteremia (PB) represents an important subset of S. aureus infection and correlates with poor clinical outcomes.
Bayer, Arnold S   +3 more
core   +1 more source

Can we prevent antimicrobial resistance by using antimicrobials better? [PDF]

open access: yes, 2013
Since their development over 60 years ago, antimicrobials have become an integral part of healthcare practice worldwide. Recently, this has been put in jeopardy by the emergence of widespread antimicrobial resistance, which is one of the major problems ...
Brown   +27 more
core   +2 more sources

Measuring antibiotic availability and use in 20 low- and middle-income countries [PDF]

open access: yes, 2020
Objective To assess antibiotic availability and use in health facilities in low- and middle-income countries, using the service provision assessment and service availability and readiness assessment surveys.
Hsia, Y   +6 more
core   +2 more sources

Impact of Model‐Informed Drug Development on Drug Development Cycle Times and Clinical Trial Cost

open access: yesClinical Pharmacology &Therapeutics, Volume 118, Issue 2, Page 378-385, August 2025.
Model‐informed drug development (MIDD) integrates data to quantify benefit/risk informing objective drug discovery and development decisions. An additional critical benefit of MIDD is postulated to be improvement in trial and program efficiencies. While the application of MIDD has grown, there have been no clear examples across programs to demonstrate ...
Vaishali Sahasrabudhe   +4 more
wiley   +1 more source

In vitro activity of ceftaroline: A novel antibiotic against methicillin-resistant Staphylococcus aureus

open access: yesIndian Journal of Pathology and Microbiology, 2016
Introduction: Staphylococcus is one of the most common causes of nosocomial infection, especially pneumonia, surgical site infections, blood stream infections, and continues to be a major cause of community-acquired infections.
Vaishali Gaikwad   +4 more
doaj   +1 more source

EFFICACY OF ARGENTUM-QUARTZ SOLUTION IN THE TREATMENT OF PERIANAL FISTULAS: A PRELIMINARY STUDY [PDF]

open access: yes, 2015
Objective: Nowadays, an optional and effective medical surgery remains the gold standard for perianal fistulas. Hereby we reported preliminary rsults in favor of using Argentum-Quartz solution for both primary and recurrent perianal fisrtulas.
Assi, TA   +9 more
core   +1 more source

Structural insights into full‐length human fascin1: a target for cancer treatment

open access: yesActa Crystallographica Section F, Volume 81, Issue 7, Page 319-331, July 2025.
This study presents the first fully resolved crystal structure of human fascin1, revealing its conformational plasticity and key interdomain interactions critical for actin bundling and cancer metastasis. These findings provide a structural foundation for the development of allosteric inhibitors and pave the way for time‐resolved crystallographic ...
Lucía Giraldo-Ruiz   +5 more
wiley   +1 more source

Use of Ceftaroline Fosamil in Osteomyelitis: CAPTURE Study Experience

open access: yesBMC Infectious Diseases, 2019
Background Osteomyelitis is often challenging to treat. This analysis examined the clinical experience of patients with gram-positive osteomyelitis treated with ceftaroline fosamil in the phase 4 Clinical Assessment Program and Teflaro® Utilization ...
Leonard B. Johnson   +2 more
doaj   +1 more source

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