Results 111 to 120 of about 6,134,485 (406)

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

A prospective, double‐blinded, randomized head‐to‐head clinical trial of topical adapinoid (oleyl adapalenate) versus retinol

Skin Health and Disease
Background Retinoids, such as retinol, are widely investigated and utilized in skin care products as a treatment for photoaging but their use is limited by tolerability. Adapinoid (oleyl adapalenate, OA) is a novel third generation retinoid that is a pro‐
Nhi Nguyen, Nasima Afzal, Mildred Min, Nabeel Ahmad, Laila Afzal, Waqas Burney, Cindy J. Chambers, Raja K. Sivamani   +7 more
doaj   +1 more source

Combining 16S Sequencing and qPCR Quantification Reveals Staphylococcus aureus Driven Bacterial Overgrowth in the Skin of Severe Atopic Dermatitis Patients [PDF]

, 2023
Amedeo De Tomassi, Anna Reiter, Matthias Reiger, Luise Rauer, Robin Rohayem, Claudia Traidl‐Hoffmann, Avidan U. Neumann, Claudia Hülpüsch, Claudia Hülpüsch   +8 more
openalex   +1 more source

SKIN GRAFTING

Dermatologic Clinics, 2000
No longer an option of last resort, skin grafting has become a technique that is routinely and sometimes preferentially considered as skin replacement for burns, chronic ulcers, and skin defects after cutaneous surgical procedures. When selected as the best alternative for wound closure, autologous skin grafts are commonly considered the gold standard.
I C, Valencia, A F, Falabella, W H, Eaglstein   +2 more
openaire   +2 more sources

Flexibly connected support and skin Patent [PDF]

, 1968
Development of resilient fastener for attaching skin of aerospace vehicles to permit movement of skin relative to ...
Leffke, W. O.
core   +1 more source

European sea bass (Dicentrarchus labrax) skin and scale transcriptomes [PDF]

, 2017
Fish skin and their appendages, the mineralized scales, are important organs for protection and homeostasis, but little is known about their specific transcript or protein repertoire.
Pinto, Patricia IS, Power, Deborah, Thorne, Michael A. S.   +2 more
core   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

Molecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris, Vasiliki Siozopoulou, Léon C van Kempen, Anne Sieben, Ella Roelant, Stig Hellemans, Elyne Backx, Laure Sorber, Koen De Winne, Senada Koljenović, Karen Zwaenepoel   +10 more
wiley   +1 more source

New changes in pregnancy and lactation labelling: Review of dermatologic drugs

International Journal of Women's Dermatology, 2019
Background: The U.S. Food and Drug Administration has published new pregnancy and lactation labelling rules that set standards on the presentation of information with regard to drug usage during pregnancy and breastfeeding, as well as the effects on ...
Yun Pei Koh, MBBS, Elizabeth A. Tian, BSc (Pharmacy), Hazel H. Oon, MD, MRCP (UK), M.Med (Int. Med), FAMS   +2 more
doaj   +1 more source

Quantitative Assessment of Angiogenesis in Skin Wound Healing by Multi-Optical Imaging Techniques [PDF]

, 2022
Lishuang Li, Yanan Sun, Honghui He, Gaiying He, Shuhua Ma, Weifeng Yang, Yi Wang   +6 more
openalex   +1 more source

Hybrid in vitro diffusion cell for simultaneous evaluation of hair and skin decontamination: temporal distribution of chemical contaminants [PDF]

, 2018
Most casualty or personnel decontamination studies have focused on removing contaminants from the skin. However, scalp hair and underlying skin are the most likely areas of contamination following airborne exposure to chemicals. The aim of this study was
A Roul, CH Dalton, D Josse, FSG Praça, G Skopp, H Eberhardt, H Matar, H Matar, HP Chan, JE Riviere, L Thors, M Houston, M Spiandore, M Spiandore, M Spiandore, N Kassouf, P Rolland, P Rolland, R Amlôt, RP Chilcott, RP Chilcott, RP Chilcott   +21 more
core   +3 more sources