Results 121 to 130 of about 6,134,485 (406)

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

Detection of gene mutation in a case of Nagashima-type palmoplantar keratoderma

open access: yesPifu-xingbing zhenliaoxue zazhi
[Objective] To report a case of Nagashima-type palmoplantar keratoderma (NPPK), identify pathogenic gene, and assist clinical diagnosis and classification of this disease. [Methods] Clinical data of the patient were collected.
CAO Yuanyuan   +5 more
doaj   +1 more source

Skin phosphocreatine [PDF]

open access: yesSkin Research and Technology, 2007
Background/purpose: The skin has the unique ability to survive ischemia associated with skin grafts, flaps and hair transplantation procedures. Spectroscopic data later confirmed by chromatography, immunohistochemistry and molecular biology techniques identified the presence of large quantities of phosphocreatine in human skin.
openaire   +2 more sources

Overview of molecular signatures of senescence and associated resources: pros and cons

open access: yesFEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas   +6 more
wiley   +1 more source

Skin-inspired highly stretchable and conformable matrix networks for multifunctional sensing

open access: yesNature Communications, 2018
Mechanosensation electronics (or Electronic skin, e-skin) consists of mechanically flexible and stretchable sensor networks that can detect and quantify various stimuli to mimic the human somatosensory system, with the sensations of touch, heat/cold, and
Qilin Hua   +7 more
semanticscholar   +1 more source

Long‐term culture of skin biopsies: maintenance of fibroblast production and competency of reprogramming

open access: yesFEBS Open Bio, EarlyView.
Skin biopsies taken from a patient with an ultra‐rare disorder as well as controls were cultured for up to 473 days. The chunks of skin were serially transferred to a new culture plate when confluent with fibroblasts. Different generations of fibroblasts were analyzed for cell and molecular properties, proliferation, and competence for reprogramming to
Sudiksha Rathan‐Kumar   +3 more
wiley   +1 more source

A Comparative Study of Engineered Dermal Templates for Skin Wound Repair in a Mouse Model [PDF]

open access: gold, 2020
Ilia Banakh   +7 more
openalex   +1 more source

Fair comparison of skin detection approaches on publicly available datasets

open access: yes, 2020
Skin detection is the process of discriminating skin and non-skin regions in a digital image and it is widely used in several applications ranging from hand gesture analysis to track body parts and face detection.
Lumini, Alessandra, Nanni, Loris
core   +1 more source

DDX3X induces mesenchymal transition of endothelial cells by disrupting BMPR2 signaling

open access: yesFEBS Open Bio, EarlyView.
Elevated DDX3X expression led to downregulation of BMPR2, a key regulator of endothelial homeostasis and function. Our co‐immunoprecipitation assays further demonstrated a molecular interaction between DDX3X and BMPR2. Notably, DDX3X promoted lysosomal degradation of BMPR2, thereby impairing its downstream signaling and facilitating endothelial‐to ...
Yu Zhang   +7 more
wiley   +1 more source

Cutaneous Nontuberculous Mycobacteria Infections Following Cosmetic Procedures: A Retrospective Study

open access: yesInfection and Drug Resistance
Rui Zeng,1,2,* Jingshu Xiong,1– 3,* Wei Gao,4 Jiayi Peng,1,2 Ying Shi,1– 3 Wenyue Zhang,1– 3 Haiqin Jiang,1– 3 Chaojiang Cheng,1,2 Gai Ge,5 Zhenzhen Wang,1,2 Youming Mei,1– 3 Zhiming Chen,6 Hongsheng Wang1– 3,7 1Hospital for Skin Diseases,
Zeng R   +12 more
doaj  

Home - About - Disclaimer - Privacy